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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 43 (1988), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A randomised, double-blind study of 100 patients admitted for daycase arthroscopy was undertaken. Fifty patients received alfentanil 500 μg and midazolam 5 mg, and 50 received alfentanil 500 μg alone, in each case 2 minutes before induction of anaesthesia with methohexitone. Anaesthesia was maintained in both groups with nitrous oxide, oxygen and enflurane. Recovery was assessed quantitatively by measuring time to when they awoke and by a comparison of pre- and postoperative performance of p-deletion and postbox tests. Qualitative assessment of recovery and of postoperative pain was also undertaken. Patients completed a questionnaire to record the incidence of any anaesthetic-related symptoms on the first and second postoperative days. Patients who received midazolam required a reduced dose of methohexitone but their initial recovery time was prolonged significantly. The incidences of anaesthetic-related side effects and postoperative pain were similar in the two groups and while the questionnaires did not reveal any statistically significant differences in symptoms on the first 2 postoperative days, the results indicated that patients who received a larger induction dose of methohexitone were subjectively drowsier on the first day after operation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Planta 155 (1982), S. 409-415 
    ISSN: 1432-2048
    Keywords: Dimethylsulphoniopropionate ; Osmotic adaptation ; Salinity (fluctuating) ; Ulva
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A study has been made of the osmotic responses of the green intertidal alga, Ulva lactuca, under two fluctuating salinity regimes; sinusoidal and square-wave fluctuations between 30 and 100% sea water in a 12 h cycle. These regimes closely resemble the tidal fluctuation of salinity encountered by the alga in its natural estuarine habitat. Data on changes in the inorganic ions, potassium, sodium, chloride and sulphate; in the organic solute, dimethylsulphoniopropionate; in the total sugar levels and estimated osmotic and turgor pressures under the two salinity regimes are reported. Significant differences in the solute responses under these different conditions were detected. In general, better control of ion fluxes appeared to be exercised under the sinusoidal conditions which also buffered changes in dimethylsulphoniopropionate levels. Influxes of potassium were highly light-dependent. Chloride levels conspicuously failed to reach the steady-state levels in the 6-h-hyper-osmotic part of either the abrupt or gradual cycle. The possible significance of these data, which may better reflect osmotic changes in the natural environment, and some of the problems encountered, particularly in accounting for charge balance under some conditions, are discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Planta 150 (1980), S. 158-165 
    ISSN: 1432-2048
    Keywords: β-Dimethylsulphoniopropionate ; Osmoregulation ; Ion relations ; Salinity ; Ulva
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The effects of hyper- and hypo-saline stresses on the levels of various inorganic and organic solutes inUlva lactuca have been recorded. Hypoosmotic stress decreased the tissue concentration of K+, Na+ and Cl- while hyper-osmotic stress caused a transient increase in Na+ and a stable accumulation of K+ and Cl-. The tissue content of β-dimethylsulphoniopropionate (β-dimethylpropiothetin) responded to changes in salinity. The time course of hypersaline stress showed the β-dimethylsulophoniopropionate concentration rose as the Na+ level fell. The levels of free sugars and amino acids, including proline, were relatively low in this alga and did not appear to be important in osmotic adjustment. The possibility that tertiary sulphonium dipolar ions have an analogous role in some algae to glycinebetaine and possibly other quaternary nitrogen compounds in higher plants as cytoplasmic osmotica is discussed briefly.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2048
    Keywords: β-Dimethylsulphoniopropionate ; Glycine betaine ; Homarine ; Osmoacclimation ; Platymonas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The tertiary sulphonium compound, β-dimethylsulphoniopropionate (DMSP) and the quaternary ammonium compounds glycine betaine and homarine are important osmotica in Platymonas subcordiformis cells. Following hypersaline stresses the compounds were accumulated after a lag period of 3 h and equilibrium concentrations were reached 6 h later. In contrast to these organic solutes, mannitol was synthesised immediately and equilibrium concentrations were reached within 90 min. Hyposaline stresses induced losses of the organic solutes from the cells. The ions K+, Na+, Cl- and the above organic solutes can account for the osmotic balance of the cells.
    Type of Medium: Electronic Resource
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