ISSN:
1279-8509
Keywords:
Lymphoblasts
;
Lymphoblastic
;
Leukemias and lymphomas
;
Adhesion molecules
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We report two cases of subcutaneous lymphomas with a study of cellular adhesion molecules compared to those expressed on blasts at a later blastic phase. The striking different profile of adhesive phenotype in the two conditions is the expression of the interactions of blasts with their microenvironments. It seems that β1 integrins-dependant pathway sustains mainly the development of hematopoietic precursors in extra-medullary niches, while their contact with bone-marrow stroma and their trans-endothelial migration implicates Selectins and Immunoglobulins molecules.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s00282-000-0160-7
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