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  • 1
    Electronic Resource
    Electronic Resource
    HIGH FREQUENCY OF THE PROPERDIN FACTOR Bf F1 AND ITS LINKAGE TO HLA IN FRENCH BASQUES (1980)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 7 (1980), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: We studied 201 unrelated French Basque individuals for HLA and Bf polymorphisms. The haplotypes of eighty-seven of them were deduced from family studies. The results show the frequency of the Bf F1 allele (0.1393) which is the highest one currently reported. They confirm the high frequencies of HLA-Aw19.2 and B18 previously reported in that population and show that a whole haplotype with strong linkage disequilibria, namely Aw19.2, Cw5, B18, Bf F1, DRw3 is frequent. On the other hand, the gene frequency of Bf S is decreased (0.5497) as compared with the other European Caucasoïd populations, while a slight increase in the Bf F gene frequency (0.2960) appears. These results point out that it is of importance to consider the genetic background in choosing the population where linkage disequilibria are to be studied.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1980.tb00739.x
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  • 2
    Electronic Resource
    Electronic Resource
    Efficiency of Searching Gm Antigens for Identification of Blood-stains in Forensic Medicine (1965)
    [s.l.] : Nature Publishing Group
    Nature 205 (1965), S. 1332-1333 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In September 1961, a suitcase containing a sum of money was stolen, and it was recovered on waste ground; its lid had been cut, probably with a sharp knife. A thorough examination revealed two very small brown-red stains, looking like blood, on the lid. A suspect arrested soon afterwards had a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2051332b0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Does a Connexion exist between Blood Group Modifications observed in Leukæmia and Certain Chromosomal Alterations? (1964)
    [s.l.] : Nature Publishing Group
    Nature 203 (1964), S. 432-433 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] As these modifications occur most often in the course of acute myelogenous leukaemias, and as there are strong reasons for believing that the alterations of the chromosomes observed in the leukaemias of this type also affect the erythroblasts, the blood group modifications are perhaps a result of a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/203432b0
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    I Antigen in Leukaemic Patients (1965)
    [s.l.] : Nature Publishing Group
    Nature 208 (1965), S. 1329-1330 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We for our part have observed, following many authors, ABO modifications in various leukaemic patients2'3. We have also observed a decrease of inhibiting power of Gm factors in these diseases. Table 1 shows our results. We should point out, however, that these modifications are almost always ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2081329b0
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  • 5
    Electronic Resource
    Electronic Resource
    Genetic linkage between Bf S0.7 (Bf S1) and HLA-Bw50 (1980)
    Springer
    Human genetics 〈Berlin〉 54 (1980), S. 417-418 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Two hundred and one unrelated French Basque individuals were studied for HLA-A, B, C, DR and Bf polymorphisms. The results show that the Bf S0.7 (Bf S1) variant, which is known to be associated with HLA-Bw21, presents a highly significant linkage disequilibrium with a subtypic specificity, i.e., Bw50 (Δ=0.0123, ΔS=100%, P〈10−8). As neither Bf S0.7 variant nor Bw50 antigen is found in Mongoloid populations, it is suggested that in evolutionary terms, the Bf S0.7 mutation is a more recent event than the HLA-Bw21 split.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00291591
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  • 6
    Electronic Resource
    Electronic Resource
    Growth and activities of enzymes of primary metabolism in batch cultures of Catharanthus roseus cell suspension under different pCO2 conditions (1988)
    Springer
    Plant cell, tissue and organ culture 13 (1988), S. 167-177 
    Details
    ISSN: 1573-5044
    Keywords: Catharanthus roseus ; cell suspension culture ; enzyme activities ; carbon dioxide partial pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In vitro enzyme activities of glycolysis, pentose-phosphate pathway and dark CO2 fixation were assayed in batch cultures of heterotrophic Catharanthus roseus cells under various gassing rates and partial pressures of carbon dioxide. Detrimental effects of low pCO2 culture conditions on the growth characteristics could be linked to marked changes in levels of enzymes of primary metabolism during growth. The enzyme levels observed during the early stages of growth were found to be more stable when a constant pCO2 (20 mbar) was maintained and enabled exponential growth to be reached more rapidly. The importance of carbon dioxide as a “conditioning factor” of the culture medium is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00043666
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  • 7
    Electronic Resource
    Electronic Resource
    Cytomegalovirus-specific B cell activation as a potential marker for the diagnosis of cytomegalovirus infection (1990)
    Springer
    European journal of clinical microbiology & infectious diseases 9 (1990), S. 745-750 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In vitro secretion of antibodies to cytomegalovirus was investigated by analysis of peripheral blood mononuclear cell culture supernatants from subjects infected with cytomegalovirus. Patients with primary or recurrent cytomegalovirus infection showed transient in vitro cytomegalovirus-specific antibody secretion. A high proportion of patients infected with human immunodeficiency virus and seropositive for cytomegalivirus showed in vitro cytomegalovirus-specific antibody secretion. All peripheral blood mononuclear cell cultures from patients with symptomatic human immunodeficiency virus infection were found to secrete in vitro antibodies to cytomegalovirus, despite the fact that isolation of cytomegalovirus from some of these patients was not achieved. In human immunodeficiency virus-infected patients, in vitro secretion of anti-cytomegalovirus antibodies appeared to be persistent. In vitro cytomegalovirus-specific antibody secretion by peripheral blood lymphocytes probably reflects an in vitro cytomegalovirus-specific B cell activation. This new assay could be considered an interesting method for detecting both acute or chronic cytomegalovirus infection, with potential use in routine laboratory practice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02184687
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    Paper (German National Licenses)
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