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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 57 (1988), S. 235-242 
    ISSN: 1439-6327
    Keywords: Blood lactate ; Supramaximal exercise ; Intermittent exercise ; Recovery O2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Blood lactate accumulation rate and oxygen consumption have been studied in six trained male runners, aged 20 to 30 years. Subjects ran on a treadmill at a rate representing 172±5% $$\dot V_{{\text{O}}_{{\text{2 max}}} }$$ for four 45 s sessions, separated by 9 min rest periods. Oxygen consumption was measured throughout. Blood lactate was determined in samples taken from the ear and $$\dot V_{{\text{O}}_{\text{2}} }$$ was measured at the end of each exercise session, and two, five and nine minutes later. After the fourth exercise session, the same measurements were made every five min for 30 min. 4 subjects repeated a single exercise of the same type, duration and intensity and the same measurements were taken. With repetitive intermittent exercise, gradual increases in blood lactate concentration ([LA]b) occurred, whereas its rate of accumulation (Δ[LA]b) decreased. The amount of oxygen consumed during each 45 s exercise session remained unchanged for a given subject. After cessation of intermittent exercise, the half-time of blood lactate was 26 min, whereas it was only 15 min after a single exercise session. $$\dot V_{{\text{O}}_{\text{2}} }$$ values, on the other hand, returned to normal after 15 to 20 min. All other conditions being equal, the gradual decrease in Δ[LA]b during intermittent exercise could be explained if the lactate produced during the first exercise session is used during the second period, and/or if the diffusion space of lactate increases. The diffusion space seems to be multicompartmental on the basis of half-time values noted for [LA]b after intermittent exercise, compared with those noted after a single exercise session. The distinction between the rapid return to normal $$\dot V_{{\text{O}}_{\text{2}} }$$ values and the more gradual return to normal blood lactate levels confirms that there is no simple and direct relationship between oxygen debt and the accumulation of blood lactate after muscular exercise. In practical terms, these results show that the calorific equivalent of lactic acid defined by Margaria et al. (1963) cannot be used in the case of intermittent exercise of supramaximal intensity.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 59 (1989), S. 73-79 
    ISSN: 1439-6327
    Keywords: Blood lactate ; Intermittent incremental exercise ; Isolated exercise ; Early lactate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Values of oxygen consumption, carbon dioxide production, ventilation and blood lactate concentration were determined in eight active male subjects during the minute following submaximal square-wave exercise on a treadmill under two sets of conditions. Square-wave exercise was (1) integrated in a series of intermittent incremental exercises of 4-min duration separated by 1-min rest periods; (2) isolated, of 4- and 12-min duration, and of intensity corresponding to each of the intermittent incremental periods of exercise. For square-wave exercise of the same duration (4 min) and intensity, no significant differences in the above-mentioned parameters were noted between intermittent incremental exercise and isolated exercise. Only at high work rate (〉92% maximal oxygen uptake), were blood lactate levels in three subjects slightly higher after 12-min of isolated exercise than after the 4-min periods of isolated exercise. Examination of these results suggests that (1) 80–90% of the blood lactate concentration observed under our experimental conditions results from the accumulation of lactate in the blood during the period of oxygen deficit; (2) therefore the blood lactate concentration/exercise intensity relationship, for the most part, appears to represent the lactate accumulated early in the periods of intermittent incremental exercise.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 62 (1991), S. 385-389 
    ISSN: 1439-6327
    Keywords: Energy cost of running ; Distance ; Fatigue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The net energy cost of running per unit of body mass and distance (Cr, ml O2·kg−1·km−1) was determined on ten amateur runners before and immediately after running 15, 32 or 42 km on an indoor track at a constant speed. The Cr was determined on a treadmill at the same speed and each run was performed twice. The average value of Cr, as determined before the runs, amounted to 174.9 ml O2·kg−1·km−1 SD 13.7. After 15 km, Cr was not significantly different, whereas it had increased significantly after 32 or 42 km, the increase ranging from 0.20 to 0.31 ml O2·kg−1·km−1 per km of distance (D). However, Cr before the runs decreased, albeit at a progressively smaller rate, with the number of trials (N), indicating an habituation effect (H) to treadmill running. The effects of D alone were determined assuming that Cr increased linearly with D, whereas H decreased exponentially with increasing N, i.e.C r =C r0+aD+He−bN. The Cro, the “true” energy cost of running in nonfatigued subjects accustomed to treadmill running, was assumed to be equal to the average value of Cr before the run for N equal to or greater than 7 (171.1 ml O2·kg−1·km−1, SD 12.7;n = 30). A multiple regression of Cr on N and D in the form of the above equation showed firstly that Cr increased with the D covered by 0.123%·km−1, SEM 0.006 (i.e. about 0.22 ml O2·kg−1·km−1 per km,P〈0.001); secondly, that in terms of energy consumption (obtained from oxygen consumption and the respiratory quotient), the increase of Cr with D was smaller, amounting on average to 0.08%·km−1 (0.0029 J·kg−1·m−1,P〈0.001) and thirdly that the effects of H amounted to about 16% of Cr0 for the first trial and became negligible after three to four trials.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 59 (1990), S. 435-442 
    ISSN: 1439-6327
    Keywords: Acute maximal exercise ; Chronic submaximal exercise ; Leucocyte populations ; Lymphocyte populations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Absolute (×103·mm−3) or relative (%) numbers of blood leucocyte types (monocytes, lymphocytes, neutrophils) and lymphocyte subsets (T11+, T4+, T8+, B1+, and NKH1+) reacting with specific monoclonal antibodies were determined at rest, immediately after maximal exercise on a treadmill, in six controls (C), and in six young cyclists before training (BT) and after 5 months of training (AT). Maximal exercise significantly increased the absolute number (mobilization) of virtually all the types of leucocytes and subsets of lymphocytes in C, BT and AT subjects. In these subjects mobilization of natural killer cells (NKH1+) and cytotoxic/suppressor T lymphocytes (T8+) was greater than mobilization of the other leucocyte types and lymphocyte subsets; however, maximal exercise induced no significant changes in the relative numbers of any leucocyte types and lymphocyte subsets, except in the case of T4+ lymphocytes in AT cyclists. Chronic submaximal exercise induced increased mobilization of neutrophils and decreased mobilization of lymphocytes during maximal exercise, except in the case of B lymphocytes (B1+) and NKH1+ cells, and decreases in the absolute and relative number of neutrophils at rest. It remains to be seen how these results can explain the modifications of leucocyte activities noted in vitro after isolated or chronic exercise.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 61 (1990), S. 223-229 
    ISSN: 1439-6327
    Keywords: Blood lactate ; Anaerobic threshold ; Previous supra-maximal exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twelve male and female subjects (eight trained, four untrained) exercised for 30 min on a treadmill at an intensity of maximal O2 consumption (% $$\dot V$$ O2max) 90.0%, SD 4.7 greater than the anaerobic threshold of 4 mmol ·1−1 (Than =83.6% $$\dot V$$ O2max, SD 8.9). Time-dependent changes in blood lactate concentration ([lab]) during exercise occurred in two phases: the oxygen uptake ( $$\dot V$$ O2) transient phase (from 0 to 4 min) and the $$\dot V$$ O2 steady-state phase (4–30 min). During the transient phase, [lab] increased markedly (l.30 mmol · l −1 · min −1, SD 0.13). During the steady-state phase, [lab] increased slightly (0.02 mmol · 1−1 · min−1, SD 0.06) and when individual values were considered, it was seen that there were no time-dependent increases in [lab] in half of the subjects. Following hyperlacticaemia (8.8 mmol -l−1, SD 2.0) induced by a previous 2 min of supramaximal exercise (120% $$\dot V$$ O2max), [lab] decreased during the $$\dot V$$ O2 transient (−0.118 mmol · 1−1 · min−1, SD 0.209) and steady-state (−0.088 mmol · 1−1 · min −1, SD 0.103) phases of 30 min exercise (91.4% $$\dot V$$ O2max, SD 4.8). In conclusion, it was not possible from the Than to determine the maximal [lab] steady state for each subject. In addition, lactate accumulated during previous supramaximal exercise was eliminated during the $$\dot V$$ O2 transient phase of exercise performed at an intensity above the Than. This effect is probably largely explained by the reduction in oxygen deficit during the transient phase. Under these conditions, the time-course of changes in [lab] during the $$\dot V$$ O2 steady state was also affected.
    Type of Medium: Electronic Resource
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