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  • 1
    Electronic Resource
    Electronic Resource
    Prevalence of pollinosis in the Basque Country (1999)
    Copenhagen : Munksgaard International Publishers
    Allergy 54 (1999), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: The prevalence of allergic diseases, mainly pollinosis, has increased within the last decades. Our study aimed to determine the prevalence of sensitization to Poaceae pollen in the Basque Country. This is a region of northern Spain, with an area of 7261 km2 and a population of 2109009 inhabitants. Two different climatic regions may be distinguished in the Basque Country (the Atlantic and the Oceanic). Methods: A transversal study was carried out on 2216 subjects, aged 10–40 years. A personal interview was carried out in order to compile study data, by means of a questionnaire that had been previously validated with a clinical history and an allergy study. Results and Conclusions: Our results show the prevalence of pollinosis in the Basque Country to be 10.6% (C.I. 95% 9.35–11.96%) without significant differences between men and women. The prevalence in the Atlantic climate area (9.71%) was lower than in the Oceanic climate area (13.61%). There were no differences between persons living in a rural environment (10.87%) and those living in an urban setting (10.51%). Pollinosis was more frequent in individuals aged 10–20 (11.41%) and 20–30 (12.54%) than those aged 30–40 years (7.43%). Three features significantly distinguished pollinic from nonpollinic patients:〈list xml:id="l1" style="custom"〉a more common complaint of symptoms after ingestion of Rosaceae fruits or nuts (10.2%)a family history of atopy (8.8%)a greater occurrence of bronchial asthmatic symptoms (23%).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.1999.00146.x
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  • 2
    Electronic Resource
    Electronic Resource
    Properties of the Ryanodine-sensitive Release Channels that Underlie Caffeine-induced Ca2+ Mobilization from Intracellular Stores in Mammalian Sympathetic Neurons (1995)
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 7 (1995), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The most compelling evidence for a functional role of caffeine-sensitive intracellular Ca2+ reservoirs in nerve cells derives from experiments on peripheral neurons. However, the properties of their ryanodine receptor calcium release channels have not been studied. This work combines single-cell fura-2 microfluorometry, [3 H]ryanodine binding and recording of Ca2+ release channels to examine calcium release from these intracellular stores in rat sympathetic neurons from the superior cervical ganglion. Intracellular Ca2+ measurements showed that these cells possess caffeine-sensitive intracellular Ca2+ stores capable of releasing the equivalent of 40% of the calcium that enters through voltage-gated calcium channels. The efficiency of caffeine in releasing Ca2+ showed a complex dependence on [Ca2+]i. Transient elevations of [Ca2+]i by 50–500 nM were facilitatory, but they became less facilitatory or depressing when [Ca2+]i reached higher levels. The caffeine-induced Ca2+ release and its dependence on [Ca2+]i was further examined by [3 H]ryanodine binding to ganglionic microsomal membranes. These membranes showed a high-affinity binding site for ryanodine with a dissociation constant (KD= 10 nM) similar to that previously reported for brain microsomes. However, the density of [3H]ryanodine binding sites (Bmax= 2.06 pmol/mg protein) was at least three-fold larger than the highest reported for brain tissue. [3 H]Ryanodine binding showed a sigmoidal dependence on [Ca2+] in the range 0.1–10 μM that was further increased by caffeine. Caffeine-dependent enhancement of [3 H]ryanodine binding increased and then decreased as [Ca2+] rose, with an optimum at [Ca2+] between 100 and 500 nM and a 50% decrease between 1 and 10 μM. At 100 μM [Ca2+], caffeine and ATP enhanced [3 H]ryanodine binding by 35 and 170% respectively, while binding was reduced by 〉90% with ruthenium red and MgCl2. High-conductance (240 pS) Ca2+ release channels present in ganglionic microsomal membranes were incorporated into planar phospholipid bilayers. These channels were activated by caffeine and by micromolar concentrations of Ca2+ from the cytosolic side, and were blocked by Mg2+ and ruthenium red. Ryanodine (2 μM) slowed channel gating and elicited a long-lasting subconductance state while 10 mM ryanodine closed the channel with infrequent opening to the subconductance level. These results show that the properties of the ryanodine receptor/Ca2+ release channels present in mammalian peripheral neurons can account for the properties of caffeine-induced Ca2+ release. Our data also suggest that the release of Ca2+ by caffeine has a bell-shaped dependence on Ca2+ in the physiological range of cytoplasmic [Ca2+].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.1995.tb00690.x
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  • 3
    Electronic Resource
    Electronic Resource
    Endocytic vesicles contain a calmodulin-activated Ca^2^+ pump that mediates the inhibition of acidification by calcium
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 1028 (1990), S. 21-24 
    Details
    ISSN: 0005-2736
    Keywords: Acidification ; Calcium ion ; Calcium pump ; Calmodulin ; Endocytic vesicle ; pH
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(90)90260-U
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  • 4
    Electronic Resource
    Electronic Resource
    The professionalization and institutionalization of 'development' in Colombia in the early post-world war II period
    Amsterdam : Elsevier
    International Journal of Educational Development 9 (1989), S. 139-154 
    Details
    ISSN: 0738-0593
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Education
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0738-0593(89)90033-3
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  • 5
    Electronic Resource
    Electronic Resource
    Double yield points in triblends of LDPE, LLDPE and EPDM (1997)
    Springer
    Journal of materials science 32 (1997), S. 549-554 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Factors that affect to the proposed mechanisms that produce the double yield phenomenon in semicrystalline polymeric materials were studied. The systems under study were ternary blends of low-density polyethylene (LDPE), linear LDPE (LLDPE) and ethylene propylene diene (EPDM). The influence on the yield mechanisms of the following different factors were analysed: processing conditions, composition, stretching rate, cooling conditions and different types of elastomers. The behaviour of these blends in the region where the double-yield points occur was found to be different for those LDPE-rich blends from those LLDPE-rich ones. These differences are explained in terms of the two mechanisms in the double yield phenomenon; that is, the slip of the crystalline blocks and the shear on the crystalline blocks. The stretching-rate effect is explained in terms of the stress relaxation time. The effects of EPDM content, cooling conditions and type of EPDM are found to be equivalent to a smaller stretching rate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018554828007
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  • 6
    Electronic Resource
    Electronic Resource
    Opuntia micropropagation by axillary proliferation (1986)
    Springer
    Plant cell, tissue and organ culture 7 (1986), S. 269-277 
    Details
    ISSN: 1573-5044
    Keywords: micropropagation ; axillary proliferation ; Opuntia amyclaea apical dominance ; sucrose effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cladode explants of Opuntia amyclaea were cultivated in Murashige and Skoog medium with different supplements. Benzyladenine was necessary for shoot development from pre-existing buds. Axillary proliferation was also stimulated in subsequent subcultures in the presence of benzyladenine and when the apical meristem was not present in the explant. The number of shoots and the total dry weight were maximum with 5% of sucrose in the medium. It was found that satisfactory rooting occurred when 5×10-5 M indole butyric acid was added to the medium. Vascular contact between roots and shoots was clearly shown by histological observations. The micropropagation system developed here allows the production in 100 days of 25 000 rooted plantlets from a single cladode, by the stimulation of axillary proliferation in the absence of apical dominance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00037744
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  • 7
    Electronic Resource
    Electronic Resource
    Effects of polyphenolic compounds on the growth and cellulolytic activity of a strain of trichoderma viride (1982)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 24 (1982), S. 983-989 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260240420
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