ISSN:
1432-2072
Keywords:
Ganglia, Basal
;
Psychopharmacology
;
Chlorpromazine
;
Amphetamine
;
Dopamine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In rats micro-injections in corpus striatum of quaternary chlorpromazine and related drugs give rise to highly characteristic neuroleptic effects: antagonism of amphetamine-induced stereotyped behaviour and development of catalepsy. There is no effect of injections in hippocampus or septum. Dopaminergic mechanisms in corpus striatum seem to play a central role in neuroleptic action.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00401348
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