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  • 1
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the course of stereotaxic thalamotomy by Leksell's open system in 20 cases of abnormal movement, recording and stimulation of the subcortical structures have been performed by means of two semimicro-electrodes introduced parallel to the frontal plane. Taking advantage of simultaneous recording and electrical stimulation through these two electrodes, several critical points in the caudate nucleus and thalamus have been clearly delineated. Thus in each individual case an outline of the thalamic configuration in the frontal plane could be obtained, so that the final therapeutic lesion was placed with good precision at the lowermost border of VL or Vim nucleus. It has been shown that the physiologically determined minimum lesion resulted in satisfactory alleviation of the abnormal movements without notable untoward effects.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 64 (1982), S. 159-166 
    ISSN: 0942-0940
    Keywords: Hydrocephalus ; subdural hygroma ; subduroperitoneal shunt ; ventriculoperitoneal shunt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three cases with unusual complications of shunting procedures are reported. These were migration of the peritoneal catheter into the mediastinum following an operation for a ventriculoperitoneal (VP) shunt, extrusion of the peritoneal catheter through a well-healed abdominal incision in an adult following a VP shunt operation, and migration of the subdural catheter into the brain substance causing increased intracranial pressure following a subduroperitoneal shunt operation. The possible mechanisms leading to the two migrations and the extrusion are discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 97 (1989), S. 117-122 
    ISSN: 0942-0940
    Keywords: Oculomotor nerve palsy ; internal ophthalmoplegia ; head trauma ; intracranial aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Six cases of internal ophthalmoplegia due to direct head injury are presented. All six patients had a dilated, nonreactive pupil. Four had no extraocular palsies or ptosis and two had partial extraocular palsies or ptosis. Disturbance of consciousness was absent or very mild, and all patients fully recovered within 1 to 7 days after the traumatic event. No patient had a history that suggested a cause for oculomotor nerve palsy, and emergency CTscans showed no mass lesions. The internal ophthalmoplegia was recognized immediately after trauma. Although minimal oculomotor nerve palsies due to unruptured intracranial aneurysms have been described, none of our patients complained of periorbital or retroorbital pain either before or after the trauma, which rules out intracranial aneurysms as the cause of the internal ophthalmoplegia. Therefore, we concluded that the internal ophthalmoplegia was due to direct head injury. The pathophysiological mechanism of the internal ophthalmoplegia appeared to be slight injury of the pupillomotor fibres on the ventromedial surface of the third nerve at the posterior petroclinoid ligament, which acted as the fulcrum due to the downward displacement of the brainstem at the time of impact.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0942-0940
    Keywords: Cerebral aneurysm ; post-operative complication ; recurrent artery of Heubner ; computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three patients with symmetrical bilateral low-density areas which were the perfusion territories of Heubner's arteries are reported. The infarctions were demonstrated on computed tomography after aneurysm surgery. Two of them had an anterior communicating artery aneurysm and the other one had multiple aneurysms of both sides. They were operated upon in the acute stage after subarachnoid haemorrhage. As common factors, a thick and diffuse subarachnoid haemorrhage, an acute-stage operation, temporary clips to bilateral A1 segments or the internal carotid artery and a relatively low systemic blood pressure during operation were found. From these findings we concluded that the pathogenesis of the infarctions was due to occlusive changes affecting Heubner's arteries bilaterally.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 74 (1985), S. 35-39 
    ISSN: 0942-0940
    Keywords: Head injury ; brain injury ; cerebral haemorrhage ; X-ray computerized tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Although delayed traumatic intracerebral haematomas (DTICH) have been frequently reported especially after the advent of computerized tomography (CT), the developmental processes of traumatic intracerebral haematomas and the incidence of DTICH have not been described precisely. Based on early sequential CT examinations of 84 intracerebral haematomas for which initial CT scans were performed as early as within 6 hours of injury, we could ascertain four types of the developmental processes: Type I (39%) included the haematomas which were already evident in the initial CT scans, Type II (11 %) the haematomas which were small or medium initially and increased their sizes afterwards, Type III (24%) the haematomas of which admisstion CT scans could not demonstrate any changes at the sites of development of the haematomas, and Type IV (26%) the haematomas of which initial CT scans showed a salt and pepper or flecked high-density appearance. Types III and IV denoted the DTICH and accounted for 50% of all the haematomas. Therefore, DTICH are thought to be not as uncommon as previously reported. Aetiologies and changes in the concepts of the DTICH are discussed, and it is stressed that, in the cases with eventual extra-and intra-cerebral combined haematomas, any surgical treatment of an extracerebral haematoma plays an important role in the development of DTICH.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0942-0940
    Keywords: Glioblastoma multiforme ; lymphokine activated killer cell ; interleukin 2 ; immunotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report the case of a 26-year-old man in whom glioblastoma multiforme had recurred six months following a subtotal resection. Despite radiotherapy and a course of interferon beta and ACNU, the tumour increased in size (to 3 cm) and there was neurological deterioration. Treatment was then initiated with LAK cells, together with ACNU and interferon beta. After three courses of LAK cells, tumour size was markedly reduced, and at about six months the tumour had nearly disappeared on computed tomographic (CT) scans. At one year, and after nine courses of LAK cell therapy (total dose of 2.7×109 cells) infused via an Ommaya reservoir and supplemented by ACNU and interferon beta, the tumour has disappeared and the patient is considered to be in complete remission since 6 months. This marked response is thought to be due chiefly to LAK cell therapy. The relatively low dose administered was well-tolerated.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 35 (1993), S. 151-155 
    ISSN: 1432-1920
    Keywords: Magnetic resonance imaging ; White matter lesions ; Cerebrovascular disease ; Age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The clinical significance of high-intensity foci in the white matter on magnetic resonance images of the brain was studied in 351 adults. The foci frequently occurred in the corona radiata and centrum semiovale. The frequency and extent of the foci were closely related to age and to a previous history of cerebrovascular disease. Patients without such a history but with risk factors for cerebrovascular disease tended to have these foci more frequently than those without risk factors.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1920
    Keywords: Intracranial aneurysm ; Subarachnoid haemorrhage ; MR angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of this study was to investigate the reliability of magnetic resonance angiography (MRA) for detection of intracranial aneurysms. Ninety-six consecutive patients who underwent both MRA using the three-dimensional time-of-flight technique (3D TOF) with the rephase/dephase subtraction method and conventional angiography were reviewed. MRA showed 22 aneurysms in 19 patients, and conventional angiography 28 aneurysms in 23 patients. The sensitivity of MRA was thus 79% for aneurysms in 83% of patients. MRA showed no aneurysm in 67 of 73 patients without aneurysms; its specificity was therefore 92%. The 6 false positive interpretations were suspected internal carotid artery aneurysms.
    Type of Medium: Electronic Resource
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