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  • 1
    Electronic Resource
    Electronic Resource
    Molecular modeling of phytochrome using constitutive C-phycocyanin from Fremyella diplosiphon as a putative structural template (1994)
    s.l. : American Chemical Society
    Bioconjugate chemistry 5 (1994), S. 21-30 
    Details
    ISSN: 1520-4812
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bc00025a004
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  • 2
    Electronic Resource
    Electronic Resource
    Structural and lattice dynamical investigation of models for reactions in organic crystals (1993)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 115 (1993), S. 6499-6505 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00068a004
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  • 3
    Electronic Resource
    Electronic Resource
    Many levels of control of V gene rearrangement frequency (2004)
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Immunological reviews 200 (2004), S. 0 
    Details
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary:  V, D, and J gene segments rearrange at very different frequencies. As with most biological systems, there are multiple levels of control of V gene recombination frequency, and here we review some of the work from our laboratory that addresses these various control mechanisms. One of the important factors that affect non-random V gene rearrangement frequency is the natural heterogeneity in recombination signal sequences (RSSs). Not only does variation in the heptamer and nonamer affect rearrangement, but variation in the spacer can also dramatically affect recombination. However, there are clearly other factors which control V gene rearrangement, as revealed by the fact that genes with identical RSSs can rearrange at different frequencies in vivo. Some of these other influences most likely affect the earliest stages of control – the change from an inaccessible state to an accessible state. Transcription factors can play a role in inducing these changes. Rearrangement of many VκI genes can be induced in a non-lymphoid cell line after ectopic expression of E2A, while neighboring VκII and VκIII genes do not rearrange, demonstrating that at least one level of control of induction of accessibility occurs at the level of the individual gene. Also, changes in chromatin structure can affect accessibility and might influence individual V gene rearrangement frequency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0105-2896.2004.00163.x
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  • 4
    Electronic Resource
    Electronic Resource
    Äquilibriometrische Befunde bei schwer sehbehinderten und blinden Kindern (1977)
    Springer
    European archives of oto-rhino-laryngology and head & neck 214 (1977), S. 339-350 
    Details
    ISSN: 1434-4726
    Keywords: Blind children ; Neurootological examination ; Electronystagmography ; Spontaneous eye-movements
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 26 of both blind or partially blind children were subjected to equilibriometric tests. By way of a vestibular-ocular test they were given the Rotatory-Intensity-Damping test. During the tests the per and postrotatory nystagmus reactions were electronystagmographicly registrated. For the vestibular-spinal tests the Unterberger's stepping test with photographic registration of the body-sway in the Cranio-Corpo-Gram was used. In most of the children you could identify a definite per and postrotatory reaction in spite of considerable spontaneous reactions. The strong eyelid movements of these patients, the intensive spontaneous deviations and diminished corneo-retinal potential made precise judgement of the electronystagmogram difficult. Comparison between the blind and partially blind children enabled the differences to be objectified. Blind-born children have a higher spontaneous activity, slightly diminished per and postrotatory nystagmus reactions and a diminished body equilibrium. These results can be explained on one side by habituation and on the other side by efferent structures, which have an inhibitory effect on the vestibular input.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00457475
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  • 5
    Electronic Resource
    Electronic Resource
    Über Verbindungen mit Urotropin-Struktur, XXII. Zur Kenntnis des Adamantyl-(1)-acetylens (1962)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 95 (1962), S. 1039-1042 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Herstellung des Adamantyl-(1)-acetylens, ausgehend von 1-Brom-adamantan und Vinylbromid über die Stufe des 1.1-Dibrom-2-[adamantyl-(1)]-äthans, wird beschrieben. Aus dieser Verbindung wurden eine Reihe charakteristischer Derivate hergestellt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19620950435
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  • 6
    Electronic Resource
    Electronic Resource
    Über Verbindungen mit Urotropin-Struktur, XXVI. Ein Beitrag zur Frage der Reaktivität von Brückenkopf -Carboniumionen (1963)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 96 (1963), S. 550-555 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Durch Ringerweiterung nach DEMJANOW wurde, ausgehend von 1-Aminomethyl-adamantan, 3-Hydroxy-tricyclo[4.3.1.13.8]undecan hergestellt. Die Solvolysenkonstanten der hieraus erhaltenen 3-Halogen-tricyclo[4.3.1.13.8]undecane wurden gemessen und mit denen der entsprechenden 1-Halogen-adamantane verglichen. Dabei wurde bei den ersteren eine um ca. 400 mal größere Reaktionsgeschwindigkeit beobachtet. Die Bedeutung dieses Befundes für die Theorie der Reaktivität von Verbindungen mit Halogen an Brückenkopf-Atomen wird diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19630960228
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  • 7
    Electronic Resource
    Electronic Resource
    Synthesen und biologische Aktivitäten von Derivaten des “thyrotropin-releasing”-Hormons (TRH) mit ω-Aminoalkylresten am Prolinamidstickstoff (1977)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1977 (1977), S. 602-608 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Synthesis and Biological Activity of Derivates of the Thyrotropin-Releasing Hormone (TRH) with ω-Aminoalkyl Residues at the Prolinamide NitrogenSyntheses of a new class of TRH derivatives of the type L-Pyr-L-His-L-Pro-NH-(CH2)n-NH2 (n = 4, 7, 10) are described. The biological activity of these TRH analogues decreases with increasing chain length.
    Notes: Die Synthesen einer neuen Klasse von TRH-Derivaten des Typs L-Pyr-L-His-L-Pro-NH-(CH2)n-NH2 (n = 4, 7, 10) werden beschrieben. Die biologische Aktivität dieser TRH-Analoga nimmt mit zunehmender Kettenlänge ab.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197719770410
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  • 8
    Electronic Resource
    Electronic Resource
    Zur Umsetzung von N-Carbonyl-sulfamidsäurechlorid mit 1.3-Dienen (1969)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 722 (1969), S. 122-131 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Reaction of Chlorosulfonyl Isocyanate with 1,3-DienesThe reaction of chlorosulfonyl isocyanate with 1,3-butadiene leads to a stable N-chlorosulfonyl-β-lactam 2 and, after hydrolysis, to 4-vinyl-2-azetidinone (3). On the other hand a number of alkyl-substituted 1,3-butadienes yield N-chlorosulfonyl-azetidinones, which are unstable in the presence of polar solvents and undergo rearrangement to 6-chlorosulfonyl-imino-δ3-dihydropyrans 7 as well as varying amounts of unsaturated N-chlorosulfonyl-δ-lactams 9 and/or unsaturated N-chlorosulfonyl carboxamides 8. Since the chlorosulfonyl group can be readily removed by hydrolysis, this reaction affords an easy route for the preparation of β-alkenyl-β-lactams and unsaturated δ-lactones.
    Notes: Die Umsetzung von N-Carbonyl-sulfamidsäurechlorid (1) mit Butadien-(1.3) führt zu einem stabilen β-Lactam-N-sulfochlorid 2 und nach der Verseifung zum 4-Vinyl-azetidinon-(2) (3). Im Gegensatz hierzu ergeben eine Reihe Alkyl-substituierter Butadiene-(1.3) umlagerungsfähige Azetidinon-N-sulfochloride, die in Gegenwart polarer Lösungsmittel instabil sind und eine Umlagerung zu 6-Chlorsulfonylimino-δ3-dihydropyranen 7 neben wechselnden Mengen ungesättigter δ-Lactam-N-sulfochloride 9 und/oder ungesättigter Carbonamid-N-sulfochloride 8 erfahren. Da die Sulfochlorid-Gruppe hydrolytisch leicht entfernt werden kann, eröffnet diese Reaktion einen präparativ einfachen Weg zu β-Alkenyl-β-lactamen und ungesättigten δ-Lactonen.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.19697220112
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