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  • 1
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Rapid transcranial magnetic stimulation is being increasingly used in the treatment of psychiatric disorders, especially major depression. However, its mechanisms of action are still unclear. The aim of this study was to assess metabolic changes by proton magnetic resonance spectroscopy following high-frequency rapid transcranial magnetic stimulation (20 Hz), both immediately after a single session and 24 h after a series of five consecutive sessions. Twelve healthy volunteers were enrolled in a prospective single-blind, randomized study [sham (n = 5) vs. real (n = 7)]. Three brain regions were investigated (right, left dorsolateral prefrontal cortex, left anterior cingulate cortex). A single as well as a series of consecutive rapid transcranial magnetic stimulations affected cortical glutamate/glutamine levels. These effects were present not only close to the stimulation site (left dorsolateral prefrontal cortex), but also in remote (right dorsolateral prefrontal cortex, left cingulate cortex) brain regions. Remarkably, the observed changes in glutamate/glutamine levels were dependent on the pre-transcranial magnetic stimulation glutamate/glutamine concentration, i.e. the lower the pre-stimulation glutamate/glutamine level, the higher the glutamate/glutamine increase observed after short- or long-term stimulation (5 days). In general, the treatment was well tolerated and no serious side-effects were reported. Neither transient mood changes nor significant differences in the outcome of a series of neuropsychological test batteries after real or sham transcranial magnetic stimulation occurred in our experiment. In summary, these data indicate that rapid transcranial magnetic stimulation may act via stimulation of glutamatergic prefrontal neurons.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    350 Main Street , Malden , MA 02148-5018 , USA and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Science Inc
    Pacing and clinical electrophysiology 28 (2005), S. 0 
    ISSN: 1540-8159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This is a report on a patient with an implanted cardioverter defibrillator (ICD) who intentionally underwent magnetic resonance imaging (MRI) of a malignant brain tumor. To avoid inadequate detection of ventricular tachycardia (VT) or ventricular fibrillation (VF), the ICD was inactivated by programming the VT-detection and VT/VF-therapy status off. The patient came through the protocol safely and without any difficulty or discomfort. There was no arrhythmic event. MRI affected neither programmed data nor the function of the ICD system.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-086X
    Keywords: Key words: Sympathectomy, lumbar—Computed tomography, guidance—Arteries, extremities—Peripheral arterial occlusive disease—Interventional procedures, complica-tions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: To prospectively analyze the effectiveness of computed tomography-guided percutaneous lumbar sympathectomy (CTLS) in patients with peripheral arterial occlusive disease in relation to angiographic findings and vascular risk factors. Methods: Eighty-three patients were treated by CTLS. After clinical evaluation of the risk profile and diagnostic intraarterial digital subtraction arteriography, 14 patients underwent unilateral, and 69 bilateral one-level treatment. Follow-up studies took place on the day following the intervention, after 3 weeks, and after 3 months. Results: A total of 152 interventions were performed in 83 patients. After 3 months, clinical examination of 54 patients (5 patients had died, 24 were lost to follow-up) revealed improvement in 46% (25/54), no change in 39% (21/54), and worsening (amputation) in 15% (8/54). There was no significant statistical correlation among any of the analyzed factors (diabetes mellitus, arterial hypertension, smoking, hyperlipidemia, obesity, hyperuricemia, number of risk factors, ankle-arm index, and angiography score) and the outcome after CTLS. Three major complications occurred: one diabetic patient developed a retroperitoneal abscess 2 weeks after CTLS, and in two other patients ureteral strictures were detected 3 months and 2 years after CTLS, respectively. Conclusion: As no predictive criteria for clinical improvement in an individual patient could be identified, CTLS, as a safe procedure, should be employed on a large scale in patients who are unsuitable for treatment by angioplasty or revascularization.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-086X
    Keywords: Key words: Fistula, esophagobronchial—Esophagus, interventional procedure—Stents and endoprostheses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A patient suffering from esophagorespiratory fistula after bougienage of a benign stricture at the site of the anastomosis between a jejunal interposition and the esophagus was referred for interventional treatment. A prototype nitinol stent centrally covered with Dacron was implanted under regional anesthesia and fluoroscopic guidance. The self-expanding prosthesis dilated the stenosis completely and closed the fistula, with consequent improvement in respiratory and nutritional status and thus the general quality of life. The patient was able to eat and drink normally until death 3 months later due to progression of his underlying malignant disease.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Medizinische Klinik 95 (2000), S. 293-298 
    ISSN: 1615-6722
    Keywords: Schlüsselwörter: Renovaskuläre Hypertonie ; Renin-Angiotensin-Aldosteron-System ; Diagnose ; Therapie ; Key Words: Renovascular hypertension ; Renin-angiotensin-aldosterone system ; Diagnosis ; Therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Background: Renovascular hypertension as a secondary form of hypertension can be improved or cured in many cases by interventional radiology or vascular surgery. Basis: The renin-angiotensin-aldosterone system and the development of hypertension are linked in renovascular hypertension. Clinical Appearance: Early clinical symptoms are of special interest in diagnosing renovascular hypertension. Diagnosis and Therapy: Nowadays, angioplasty or stenting have mostly replaced surgery in view of treatment of renovascular hypertension. Conclusion: Renovascular hypertension, if diagnosed early, can be improved or cured in many cases regarding hypertension and/or renal insufficiency.
    Notes: Zusammenfassung Hintergrund: Der renovaskulären Hypertonie kommt besondere Bedeutung zu, da sie als sekundäre Hypertonieform durch interventionell-radiologische oder gefäßchirurgische Maßnahmen in vielen Fällen erfolgreich therapierbar und zum Teil auch heilbar ist. Grundlagen: Die Entstehung einer renovaskulären Hypertonie ist ursä,chlich mit dem Renin-Angiotensin-Aldosteron-System verknüpft. Klinik: Klinische Hinweise bzw. Krankheitszustände sind von großer Bedeutung für die frühzeitige klinische Verdachtsdiagnose einer renovaskulären Hypertonie. Diagnostik und Therapie: Eine renovaskuläre Hypertonie kann interventionell-radiologisch (Angioplastie oder Stentversorgung), chirurgisch oder medikamentös therapiert werden. Schlußfolgerung: Eine renovaskuläre Hypertonie kann bei frühzeitiger Diagnosestellung unter den Gesichtspunkten Hypertonie und Niereninsuffizienz in vielen Fällen geheilt oder gebessert werden.
    Type of Medium: Electronic Resource
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