ISSN:
1432-1041
Keywords:
propranolol
;
plasma ammonia
;
exercise
;
healthy volunteers
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Changes in plasma ammonia in response to exercise with and without pretreatment with propranolol have been studied. A standardised submaximal treadmill exercise test was used to assess the effects of placebo or propranolol 40 mg, 80 mg, or 160 mg twice daily given in random order for 3 days, the last dose being taken 90 min before exercise. After placebo the mean incremental rise in plasma ammonia in response to exercise was 16 µmol·l−1. The corresponding rise after propranolol 40mg was 56 µmol·l−1 (p〈0.01). All three doses of propranolol produced similar effects on plasma ammonia and exercise heart rates.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00542187
Permalink