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  • 1
    Electronic Resource
    Electronic Resource
    Ultrastructure of Early Pigmentary Changes in Dowling-Degos' Disease (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 7 (1980), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Dowling-Degos' anomaly is characterized by a reticular and spotted pigmentation of the skin folds; this pigmentary disturbance, occurring most often in women, is a dominant inherited genodermatosis which worsens progressively and may exhibit in the early phase rapid changes in severity after emotional stress. In a 9-year-old girl, an electronmicroscopic study of pigmented lesions showed a strong melanocytic activity with quantitative increase of the melanosomes; the average size of the melanosomes was not different when compared to normal Caucasoid skin, but in the keratinocytes they were distributed according to a dispersed pattern as in black skin. The pigmentary state of Dowling-Degos' disease is another example of melanocyte-keratinocyte interaction where the epidermal melanin pattern and the size of pigment granules are not in striking correlation. An accelerated rate of melanogenesis and pigmentation may be another factor determining a non-aggregated distribution of the melanosomes within the keratinocytes. The nature of the stimulus of pigmentation in these skin areas which are not sun-exposed is still unclear.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1980.tb01186.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    ISOLATION OF EPIDERMAL LANGERHANS CELLS (1989)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 16 (1989), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Langerhans cells (LC) play an important role in the skin immune system. They are bone marrow-derived and function as the only accessory and antigen-presenting cells in the skin. Several techniques for enriching these cells have been devised, and four, including density gradient centrifugation, use of cell sorter, panning and immunomagnetic separation, are discussed. It is concluded that the most satisfactory method for isolation of LC is based on density gradient centrifugation and the most satisfactory for depletion of epidermal cell preparations for LC is based on the immunomagnetic principle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1989.tb00458.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Trichilemmal Tumor Undergoing Specific Keratinization (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 6 (1979), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Numerous tumors with follicle-like direction of differentiation have been described. At least three of them connected to the overlying epidermis are related to the outer root sheath or trichilemma: the tumor of follicular infundibulum (Mehregan & Butler 1961) and the inverted follicular keratosis (Helwig 1955) or follicular poroma (Duperrat & Mascaro 1963) have been related to the infundibulum, the tricholemmoma (Headington & French 1961) to the lower outer root sheath. On the occasion of a case first diagnosed as proliferating trichilemmal cyst of the scalp, we think we have individualized a tumor exhibiting ability to undergo trichilemmal keratinization. We describe its histogenesis and stress its peculiarities compared with other lesions showing trichilemmal keratinization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1979.tb01172.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Perforating lichen planus (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 11 (1984), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We describe a case of perforating lichen planus. The foreign material eliminated by this path appears to be represented by the numerous hyaline bodies present at the base of the perforation. This unusual variant may be added to the many variants of lichen planus previously described: atrophic, hypertrophic. planopilaris, bullous etc…
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1984.tb00370.x
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  • 5
    Electronic Resource
    Electronic Resource
    Antigen-presenting cells and tolerance induction (2002)
    Oxford, UK : Blackwell Science, Ltd
    Allergy 57 (2002), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: T cell tolerance induction to foreign and self-antigens has occupied research since the beginning of the understanding of the immune system. Much controversy still exists on this question even though new methods became available to investigate immunoregulatory mechanisms. Antigen-presenting cells play a pivotal role in transferring information from the periphery of the organism to lymphoid organs. There, they initiate not only the activation of naive T cells but seem to deliver important signals which result in T cell unresponsiveness with antigen-specific tolerance induction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0105-4538.2001.00001.x-i4
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  • 6
    Electronic Resource
    Electronic Resource
    Histiocytosis-X cells express C3b, C3d, and C3bi receptor (CR1, CR2, and CR3) antigens (1985)
    Springer
    Archives of dermatological research 277 (1985), S. 496-498 
    Details
    ISSN: 1432-069X
    Keywords: Histiocytosis X ; C3b Receptor ; C3d Receptor ; C3bi Receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00510069
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    Paper (German National Licenses)
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