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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 415 (1989), S. 357-366 
    ISSN: 1432-2307
    Keywords: Paraquat poisoning ; Pulmonary fibrosis ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty-nine autopsy cases of paraquat-induced lung injury were studied by histological and immunohistochemical methods. Two stages of injury were identified. In the early stage, the alveolar epithelium degenerates but the epithelial basement membrane remains intact. In the late stage, the epithelial basement membrane is focally disrupted, the mesenchymal cells grow into the alveolar space, and intra-alveolar fibrosis appears. In spite of these pathological changes, the original framework of the alveolar wall is preserved in many areas. Intra-alveolar fibrosis may follow as a consequence of damage to the epithelium without severe damage to the underlying basement membrane, which occurs at the stage of organization. Morphological variants of intra-alveolar fibrosis seem to occur not only to the size of the defect of the basement membrane but also to the difference in the stages of evolution at the time the lesion is studied. The epithelium regenerates along the basement membrane in the early stage of re-epithelialization, but grows over the luminal aspect of intra-alveolar fibrous tissue which has been laid on the remaining basement membrane in the late stage. It is speculated that the regeneration of epithelial cells may develop without any association with the basement membrane when a fibrous tissue covers the original basement membrane.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2711
    Keywords: seek test ; pole tip ; wear ; roughness ; environment ; read‐back signal degradation ; magnetic performances ; cyclotriphosphazene ; carbon film
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The read‐back signal degradation in seek motion with a pseudo‐contact head in a hard disk drive was studied. It was found by AES analysis that the pole tip surface of NiFe was covered with a decomposed layer of NiFe and carbon following seek motion. The read‐back signal degradation became larger with increasing thickness of the decomposed layer. An MFM study of the seek‐tested pole tip surface showed that the magnetic properties of the pole tip surface deteriorated by seek motion, and that the read‐back signal degradation increased with increase of deterioration of the magnetic properties of the pole tip surface. These results suggest that either the poor permeability of the decomposed layer on the pole tip surface and increase of spacing between the fresh pole tip surface under the decomposed layer and the disk surface decrease the flux flow from the disk magnetic layer into the pole tip, or that the decomposed layer on the gap short‐circuits the flux flow. It was found that the additive, cyclotriphosphazene, in a lubricant film, and a protective layer of carbon on a slider surface drastically reduced degradation.
    Type of Medium: Electronic Resource
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