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  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. A retrospective population study in Northern Ireland examined the benefits of centralized care in insulin-dependent diabetic pregnancies. In the 5 years 1979–1983, there were 139 250 deliveries in Northern Ireland and of these 221 pregnancies occurred in 187 insulin-dependent diabetic patients; 100 were managed entirely in peripheral maternity units, 61 were referred from a peripheral unit to the Royal Maternity Hospital, Belfast and 60 were managed entirely in this central referral hospital. The patients referred from the periphery had the worst past obstetric history with a combined perinatal mortality rate of 200 per 1000. During the study period the perinatal mortality rate was 107 for the referred pregnancies, 33 for those managed entirely in the peripheral units and 18 for those managed at the Royal Maternity Hospital. If those pregnancies terminated for fetal abnormality, and deaths beyond the perinatal period are included, the figures for total fetal loss were 15.5%, 5.5% and 7.1% respectively. Overall the major congenital malformation rate was 7.5%, and for the respective groups 6.5%, 3.0% and 13.0%. For the general population during the same period the perinatal mortality rate was 1.4% and the major congenital malformation rate was 2.5%. Thus it is suggested that only peripheral hospitals which can offer combined antenatal/endocrine care and with a neonatal intensive care unit should undertake the management of the pregnant diabetic.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 74 (1967), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0428
    Keywords: Glucose tolerance test ; oral GTT ; cortisone GTT ; I.V. GTT ; pregnancy ; potential diabetes ; latent diabetes ; gestational diabetes ; foetal results ; perinatal mortality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les résultats des tests de tolérance au glucose dans un groupe sélectionné de 1718 patientes étudiées au cours de la trente-deuxième semaine de gestation sont comparés 1. principalement au poids maternel, et 2. en partie à l'âge maternel, à la maturité foetale et au poids foetal lors de la délivrance. Aucune préférence nette n'apparaît entre les trois tests, mais la valeur K (vitesse de disparition du glucose après glucose i.v.) est la plus sensible aux variables étudiées. Il n'est pas possible de prédire les conséquences sur le foetus à partir de l'information obtenue d'un test de tolérance au glucose effectué à la trente-deuxième semaine de gestation.
    Abstract: Zusammenfassung Die Glucosetoleranz-Tests bei einem ausgewählten Kollektiv von 1718 Frauen die in der 32. Schwangerschaftswoche durchgeführt wurden, werden a) vor allem durch das Gewicht der Mutter, b) z.T. aber auch durch ihr Alter, den Reifegrad des Foeten bei der Entbindung und sein Geburtsgewicht beeinflußt. Eindeutige Vorzüge ließen sich für keinen der 3 Tests ermitteln, doch scheint von den untersuchten Variablen der Wert (Glucose-Schwundrate nach i.v. Injektion) am empfindlichsten zu sein. Über das Schicksal des Foeten lassen sich an Hand eines in der 32. Schwangerschaftswoche durchgeführten Glucosetoleranz-Tests keine Voraussagen machen.
    Notes: Summary Results of glucose tolerance tests in a selected group of 1718 patients studied at the thirty-second week of gestation are related, a) mainly to the maternal weight, and b) in part to the maternal age, foetal maturity at delivery and foetal weight at delivery. No clear preference between the three tests emerges, but the K value (glucose disappearance rate after I.V. glucose) appears to be most sensitive to the variables studied. It is not possible to predict the foetal outcome with information obtained from a glucose tolerance test carried out at the thirty-second week of gestation.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0428
    Keywords: Emotional and academic achievement ; children of diabetic mothers ; Type 1 diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary No difference was found at paediatric assessment, or by a psychologically-based maternal and teacher questionnaire of the emotional state or academic achievement, between 123 children of Type 1 (insulin-dependent) diabetic mothers and 124 children of non-diabetic mothers. The groups were closely matched for maternal age, sex and position in sibship of the child, and age and home environment of the mother. The children of diabetic mothers had all been delivered before week 38 of gestation.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Diabetologia 32 (1989), S. 236-239 
    ISSN: 1432-0428
    Keywords: Urinary albumin excretion ; diabetic pregnancy ; microalbuminuria ; pre-eclampsia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have analysed the results of urinary albumin excretion in timed overnight urine samples once every two weeks during pregnancy and post-natally in 25 non-diabetic women and 14 women with Type 1 (insulin-dependent) diabetes who were Albustix negative and had urinary albumin excretion 〈15 μg· min−1 at conception. Urinary albumin excretion did not vary significantly in the first two trimesters in either group and at 28 weeks was 2.73 μg·min−1 (0.32–251.68) (median and range) in the diabetic women and 2.53 μg·min−1 (0.90–13.37) in control patients (not significant). During the third trimester urinary albumin excretion increased, and levels were significantly higher in diabetic patients from 36 weeks (9.37 (0.9–31.78) vs 3.52 (0.19–33.74) μg· min−1, p〈0.01) until delivery. In both groups, urinary albumin excretion reached a peak within the week following delivery — diabetic 17.42 μg·min−1 (2.03–46.64), control subjects 16.29 μg· min−1 (1.53–35.56), but six weeks after delivery, levels were similar to those in early pregnancy. The effect of pregnancy on urinary albumin excretion in these diabetic women would appear to be an exaggeration of the normal pattern, with levels returning to normal post-delivery. It is not possible to know if this has significance for future renal function, but it would be important to investigate this phenomenon in patients who already have raised urinary albumin excretion at conception.
    Type of Medium: Electronic Resource
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