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  • 1
    Electronic Resource
    Electronic Resource
    Microbial conversion of sterols (1982)
    Springer
    Applied microbiology and biotechnology 15 (1982), S. 25-32 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract By preselection of microorganisms which preferentially attack the side chain of cholesterol we have been able to isolate a mutant of Corynebacterium spec. Chol 73 which forms 20-carboxy-pregna-1,4-dien-3-one (BNC) from cholesterol in nearly quantitative yields. The structure of this compound has been established by means of13C NMR-,1H NMR and CD spectroscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01875396
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Studies on the formation of long-chain dicarboxylic acids from puren-alkanes by a mutant ofCandida tropicalis (1986)
    Springer
    Applied microbiology and biotechnology 24 (1986), S. 168-174 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Individualn-alkanes, from C11−C16, were metabolized by a mutant ofCandida tropicalis. This strain was selected for its inability to grow in the presence of dodecanedioic acid and dodecane as the sole carbon source. Transformations were studied in fed-batch cultures. Undecane was only poorly transformed, but from dodecane to hexadecane high transformation yields were achieved. Maximum yield of acid-precipitable long-chain dioic acids was obtained with tridecane as substrate. All the products were mixtures of different acids. Besides the α,ω-alkanedioic acids, the 3-hydroxy derivatives of long-chain α,ω-alkanedioic acids and dioic acids with a shortened carbon chain were found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01982562
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Studies on the formation of long-chain dicarboxylic acids from puren-alkanes by a mutant ofCandida tropicalis (1986)
    Springer
    Applied microbiology and biotechnology 24 (1986), S. 168-174 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Individualn-alkanes, from C11−C16, were metabolized by a mutant ofCandida tropicalis. This strain was selected for its inability to grow in the presence of dodecanedioic acid and dodecane as the sole carbon source. Transformations were studied in fed-batch cultures. Undecane was only poorly transformed, but from dodecane to hexadecane high transformation yields were achieved. Maximum yield of acid-precipitable long-chain dioic acids was obtained with tridecane as substrate. All the products were mixtures of different acids. Besides the α,ω-alkanedioic acids, the 3-hydroxy derivatives of long-chain α,ω-alkanedioic acids and dioic acids with a shortened carbon chain were found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00938790
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Specific enrichment of mutants of Escherichia coli with an altered acyl CoA synthetase by tritium suicide (1972)
    Springer
    Molecular genetics and genomics 117 (1972), S. 143-152 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In a rich growth medium, tritium-labelled oleate is incorporated preferentially into the lipid fraction of E. coli K12. The incorporation of the radioactive oleate after a temperature shift kills the majority of the cells during subsequent storage. Most of the surviving cells can no longer grow with oleate as the sole carbon source at 40°C or 30°C, though some exhibit a thermosensitive behaviour, and are able to grow at 30°C but not at 40°C. It will be shown that mutants of the first group lack the enzyme acyl CoA synthetase, and that this enzyme is thermolabile in mutants of the second group. In addition one further mutant was isolated which possessed a normal acyl CoA synthetase but which was unable to degrade or incorporate oleic acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00267611
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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