ISSN:
1432-0614
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Summary Following growth on n-alkanes, undecanoic acid in high concentrations completely inhibits the acylation of fatty acids formed during the terminal oxidation so that the intracellular fatty acid pattern is composed exclusively of components from the de novo synthesis. An inhibitory effect of undecanoic acid stems presumably from the effect it has on the long-chain acyl-coenzyme A synthetase I, whereas the corresponding long-chain acyl-coenzyme A synthetase II, which is bound to specific cell organelles remains untouched by this inhibition. The strongly reduced growth, even following glucose oxidation, probably comes from the effect of C11-acid on specific intramitochondrial situated enzymes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00252592
Permalink
