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  • 1
    Electronic Resource
    Electronic Resource
    Transfusionsmalaria als Ursache von unklarem postoperativen Fieber (1998)
    Springer
    Monatsschrift Kinderheilkunde 146 (1998), S. 1054-1056 
    Details
    ISSN: 1433-0474
    Keywords: Schlüsselwörter Bluttransfusion ; Malaria ; Fieber unklarer Genese ; Malariatherapie ; Key words Blood-transfusion ; Malaria ; Fever of unknown origin ; Malaria therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary An 18 month old boy developed septic fever 14 days after surgery not responding to antibiotic treatment. The cause was found to be a transfusion transmitted infection with plasmodium falciparum. The patient completely recovered after anti-malaria treatment with quinine and halofantrine. Discussion: In cases of unclear septic illness up to 3 month after a blood transfusion, a transfusion malaria should be included in the differential diagnosis. The mortality rate is 15%. Early treatment can prevent a lethal outcome.
    Notes: Zusammenfassung Wir berichten über einen 18 Monate alten Jungen, der 14 Tage nach einer Operation ein Antibiotika-refraktäres, septisches Krankheitsbild entwickelte. Als Ursache fand sich eine durch Bluttransfusion übertragene Infektion mit Plasmodium falciparum. Nach Therapie dieser Transfusionsmalaria mit Chinin und Halofantrin kam es zur vollständigen Heilung. Diskussion: Bei unklarem septischen Krankheitsbild bis zu 3 Monate nach einer Transfusion muß auch an eine transfusionsbedingte Malaria gedacht werden. Die Mortalität beträgt bis zu 15%. Durch die rechtzeitige Therapie kann ein letaler Ausgang verhindert werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001120050363
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  • 2
    Electronic Resource
    Electronic Resource
    Cryohemolysis test as a diagnostic tool for hereditary spherocytosis (1999)
    Springer
    Annals of hematology 78 (1999), S. 555-557 
    Details
    ISSN: 1432-0584
    Keywords: Key words Hemolytic anemia · Hereditary spherocytosis · Erythrocyte enzyme deficiency · Cryohemolysis test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The cryohemolysis test has been proposed as a new method of identifying hereditary spherocytosis. The purpose of the present study was to analyze the sensitivity and specificity of this method in comparison to the measurement of osmotic fragility. The examination included 61 patients suffering from hereditary spherocytosis and 58 patients with other hemolytic and nonhemolytic anemias. Hereditary spherocytosis patients showed significantly higher cryohemolysis values (median 29.7%, range 12.3–50.2%) than both normal subjects (median 3%, range 0.5–27%) and all other anemic patients excepting those with immune hemolytic anemia (median 4%, range 0.5–10.1%). Analysis of immune hemolytic anemia revealed broadly scattered values ranging from 1.4% to 53.5% (median 8.6%). Taking 15% as the threshold value, the sensitivity and specificity of the cryohemolysis test for hereditary spherocytosis were 95% and 96%, respectively. It is concluded that the simple-to-perform cryohemolysis test is quite comparable to the estimation of red cell osmotic fragility and therefore very useful as a diagnostic measure of hereditary spherocytosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770050557
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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