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  • 1
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An air-core superconducting solenoid, with a diameter of 0.2 m and a length of 0.4 m, has been configured for use as a heavy-ion reaction-product spectrometer (E/A≤5 MeV/u) near θ=0 °. The spectrometer has a large solid angle (10–35 msr) and properties suitable for time-of-flight measurements with flight paths (approximately-greater-than) 2 m. The performance of the spectrometer was established using α-particle sources and nuclear-reaction products from heavy-ion collisions. The characteristics of air-core magnets are compared to those of steel-yoke magnets. The simplicity and ease of operation of the air-core magnet, without significant problems from the (axial) fringe fields, suggests that larger air-core magnets with dΩ≥20 msr and capable of focusing ions with E/A≥30 MeV/u are feasible. Other applications of solenoids and combinations of solenoids with radial electric-field lenses (ELCO lenses) are also discussed, including designs which focus more than one charge state simultaneously.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford BSL : Blackwell Science Ltd
    Molecular microbiology 21 (1996), S. 0 
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The lateral transfer of genetic information among microorganisms is a major force driving the outstanding adaptability of microbial communities to environmental changes. Until now little information has been obtained on gene transfer in natural ecosystems. We present here a genetic circuit for detecting and quantifying horizontal gene transfer from a defined donor microorganism to recipient organisms in the absence of selection for a recipient-specific phenotype. The system consists of an engineered lacZ (encoding β-galactosidase) reporter gene whose expression is controlled by a synthetic regulatory element based on a fusion between the Pr promoter-operator from lambda bacteriophage and the 5′ non-coding leader region of the tnp gene encoding the IS10 transposase function. Expression of this reporter cassette in the recombinant microorganism is completely shut down by two chromosomally encoded trans-acting repressors working at the level of transcription (the CI-EK117 protein from the lambda phage), and at the level of translation (the antisense RNA-OUT of the IS10 element). When the reporter element is transferred to a different host by any mechanism, it escapes repression and becomes expressed. The system was validated with Pseudo-monas putida, and conjugational transfer frequencies of the reporter element as low as 10−6 were detected. The modular design and broad host range of the genetic circuit, in combination with biomarkers which permit real-time in situ detection, will facilitate the monitor-ing of gene flow in a non-disruptive manner within the environment.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 40 (1962), S. 467-470 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Bei sechs extrakorporalen Dialysen (an vier Patienten) wurde eine isolierte Heparinisierung des extrakorporalen Kreislaufes nachGordon u. Mitarb. angewandt, wobei zwei getrennt steuerbare Infusionen von Heparin und Protaminsulfat während der Dialyse zum Einlauf kamen. Neben Dosierungsangaben für die Heparin- und Protaminsulfat-Infusionen wird über das Verhalten des Heparinblutspiegels sowie der Gesamtgerinnung im Organismus und im Dialysator berichtet. Bei einer Heparinisierung von etwa 0,75–1,0 IE Heparin pro Milliliter Blut (bei einem Umlaufminutenvolumen von 200 ml/min) und einer Protaminsulfatdosierung von etwa 10–15 γ/ml Blut liegt der Heparingehalt im Organismus mit etwa 1–2 γ/ml Blut äußerst niedrig. Daraus ergibt sich, daß die Gesamtgerinnung, gemessen mit der Recalcifizierungszeit, im Körperblut nur unwesentlich gegenüber der Norm verzögert ist. Dagegen zeigte die Recalcifizierungszeit mit Werten von etwa 300 sec eine ausreichende Gerinnungshemmung im Dialysatorblut. Es konnte somit gezeigt werden, daß es mit dieser Methode gelingt, den Heparinblutspiegel im Organismus während extrakorporaler Dialyse äußerst niedrig zu halten, so daß eine schwere Blutungsbereitschaft keine absolute Kontraindikation zur Durchführung einer extrakorporalen Dialyse darstellt.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 7 (1919), S. 619-625 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 7 (1919), S. 636-639 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal for general philosophy of science 15 (1984), S. 354-371 
    ISSN: 1572-8587
    Source: Springer Online Journal Archives 1860-2000
    Topics: Philosophy , Nature of Science, Research, Systems of Higher Education, Museum Science
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 28 (1940), S. 473-475 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 160 (1960), S. 171-185 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A compilation of the known data on Coulomb energy differences of isobaric doublets and isobaric triplets is given. Plots of the Coulomb energy differences versus¯Z/A 1/3 with¯Z=(Z 1+Z 2)/2 show an analogous shell structure behaviour for the three series with 2¯Z=A−1,A andA+1 (T=1, 1/2 and 1), i.e. discontinuities at the closed shells atA=4, 16 and 40 and the closed subshell atA=32 and oscillations mainly being due to Coulomb proton-proton pairing energy. A positive energy shift of the lowest states withT=1 of all self-conjugate nuclei withA=4n+2 seems to be indicated by the experimental data. A semi-empirical formula is given that describes the data.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 196 (1966), S. 477-485 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A new type of plot for the Coulomb energy differences between isobaric analogue states of neighboring isobaric nuclei withT z =T−1 andT z =T is introduced. The available experimental data when displayed in this form reveal nuclear structure effects.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 256 (1972), S. 236-242 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Arguments are presented which show that the transverse and longitudinal nuclidic mass relationships of Garvey and Kelson (GK-T and GK-L) contain small but systematic errors. If masses far off the line of β-stability are calculated, these errors accumulate in the repeated application of the relationships, and the diverging predictions from GK-T and GK-L seem to represent estimates of upper and lower limits only. A new generalized nuclidic mass relationship is introduced.
    Type of Medium: Electronic Resource
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