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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 89 (1982), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Gall bladder volume was measured by ultrasound in eight patients with cholestasis of pregnancy, in 21 normal pregnant women and in 14 non-pregnant women, and at the same time serum cholic and nodeoxycholic acid levels were estimated. The gall bladder volume was 60% larger in cholestasis than that in normal pregnancy and more than two times larger in normal pregnancy than in non-pregnant women. The serum cholic and chenodeoxycholic acid concentrations were significantly higher in cholestasis of pregnancy than those in normal pregnancy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 83 (1976), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In order to study the function of the pituitary-adrenal axis, serum ACTH and cortisol levels were estimated before and after insulin induced hypoglycaemia in nine women with hyperemesis gravidarum, seven women in normal early pregnancy and in eight non-pregnant controls. Before hypoglycaemia, the basal ACTH level in the hyperemesis group (102.4±62.9 pg/ml) was higher than in normal early pregnancy (67.5±19.2 pg/ml; p〈0.05) or in non-pregnant controls (54.8±25.2 pg/ml; p〈0.01). Correspondingly, the mean cortisol value in hyperemesis (0.47±0.16 μmol/1) was higher than in normal early pregnancy (0.39±0.10 μmol/1; p〉0.05) or in non-pregnant controls (0.32±0.13 μmol/1; p〈0.01). After insulin the elevation of ACTH (p〉0.05) and cortisol (p〈0.01) was observed in every group. The level of ACTH and cortisol was highest in hyperemesis group. Our results do not support the idea that hypofunction of the pituitary-adrenal axis contributes to the aetiology or pathogenesis of hyperemesis gravidarum. The high ACTH level might be evidence of the psychic instability of hyperemesis gravidarum patients.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The levels of free amino acids in amniotic fluid were determined in twenty patients with normal pregnancy, five with intrahepatic cholestasis of pregnancy, twelve with pre-eclampsia, and four with rhesus incompatibility. In pre-eclampsia there was no significant change in the amino acid composition of the amniotic fluid. In recurrent intrahepatic cholestasis the concentration of 15 out of the 22 amino acids studied was significantly higher than normal and the mean concentration of 4 others was more than 20 per cent above normal without this being statistically significant. In rhesus incompatibility there was a significant decrease in the concentration of 13 amino acids, and a decrease of more than 20 per cent in the mean concentration of 5 others.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The 15-methyl analogue of PGF2α was administered intramuscularly between 23 and 36 weeks of gestation, to induce labour in 11 mothers with intrauterine fetal death and two with anencephaly. All were delivered within 20 hours (mean 7 hours). The mean dose of 15-me-PGF2α was 400 μg (range 100 to 700) given by a mean of 3·1 (range 1 to 7) injections. Diarrhoea was the most frequent sideeffect.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 80 (1973), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Serum HPL levels were determined in the supine and upright positions at two-hour intervals in normal and complicated late pregnancies. No significant difference could be demonstrated.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 64 (1957), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 72 (1999), S. M050 
    ISSN: 1432-1246
    Keywords: Key words Triethylamine ; Contrast sensitivity ; Visual symptoms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: The objective was to define the dose-response for triethylamine (TEA) vapour-induced visual changes. Methods: Four core makers were exposed in a dynamically-controlled whole-body chamber to TEA for 4 h at the concentrations of 40.6, 6.5 and 3.0 mg/m3. Before and after the exposure binocular visual acuity and contrast sensitivity at 2.5% contrast were measured. The visual measurements were carried out with the use of optotype test charts (Precision Vision, Villa Park, Ill. USA). The outcome was determined as a change in the rows of the test chart. Results: Visual acuity decreased in three of the four subjects after 40.6 mg/m3 TEA exposure, and remained at the pre-exposure level after 6.5 and 3.0 mg/m3 exposures. Contrast sensitivity at 2.5% contrast decreased in the same three subjects after 40.6 and 6.5 mg/m3 TEA exposures but remained at the pre-exposure level in all subjects after the TEA exposure of 3.0 mg/m3. Conclusions: TEA exposure over 4 h at the concentration of 3.0 mg/m3 in air caused no changes in contrast sensitivity. A corresponding exposure at the concentration of 6.5 mg/m3 caused deterioration in contrast sensitivity in most subjects. Because the blurring of vision occurs within 4 h after the start of working with TEA the results can probably be applied for the setting of an 8 h occupational exposure limit. Moreover, the results are consistent with the current 4.1 mg/m3 ACGIH TLV.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 56 (1978), S. 801-804 
    ISSN: 1432-1440
    Keywords: Thrombose ; Streptokinase ; Thrombosis ; Streptokinase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Fourty-four patients with deep venous thrombosis of the leg diagnosed by phlebography and not more than five days old were treated with streptokinase. Oral anticoagulant therapy was started at the same time. Complete lysis of thrombi was obtained in 6 cases and partial one in 25 cases. Lysis of proximal thrombi was better than that of distal ones. The age of the thrombi had no effect on the lysis. Urticaria and anaphylactic reactions occurred in 8 patients and treatment was discontinued. Haemorrhagic complications were present in 8 cases but remission was obtained by discontinuing streptokinase infusion. Commencing oral anticoagulant therapy simultaneously with streptokinase reduces duration of treatment without increasing the risks and the results of lysis are equally good as with earlier studies. The use of streptokinase is recommended in the treatment of proximal deep venous thrombosis. This treatment offers a possibility of preventing a postthrombotic syndrome. The frequency of various complications should however be borne in mind.
    Notes: Zusammenfassung 44 Patienten mit einer phlebographisch diagnostizierten, höchstens 5 Tage alten Thrombose der tiefen Unterschenkelvenen wurden mit Streptokinase behandelt. Gleichzeitig wurden außerdem orale Antikoagulantien eingesetzt. Eine vollständige Thrombolyse wurde in 6, und eine partielle Thrombolyse in 25 Fällen erreicht. Proximale Thromben wurden besser lysiert als distale. Die Auflösung zeigte keine Korrelation mit dem Alter der Thromben. Bei 8 Patienten manifestierten sich Urtikaria und anaphylaktische Reaktionen, die die Einstellung der Therapie erforderten. In 8 Fällen kam es zu hämorrhagischen Komplikationen, die jedoch durch Absetzen der Streptokinase beseitigt werden konnten. Die Kombination von Streptokinase mit oralen Antikoagulantien verkürzt die Therapiedauer, ohne jedoch das Risiko zu erhöhen; die lytische Wirksamkeit entspricht derjenigen der früheren Studien. Streptokinase wird für die Behandlung von proximalen Thrombosen der tiefen Venen empfohlen. Sie bietet eine Möglichkeit zum Schutz vor der Entwicklung eines postthrombotischen Syndroms. Das Auftreten von verschiedenen Komplikationen sollte jedoch beachtet werden.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 345 (1977), S. 614-614 
    ISSN: 1435-2451
    Keywords: Hemorrhoidectomy ; Cryosurgery ; Hämorrhoidektomie ; Kryochirurgie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: ZusammenfaBung 53 aufeinanderfolgende Fälle von Hämorrhoiden vom Grad 11 und III wurden mittels Kryochirurgie behandelt. Die Beobachtungsperiode hatte eine Dauer von 3–12 Monaten und ein gutes Ergebnis wurde in 96% verzeichnet. Die Patienten verweilten über Nacht im Krankenhaus. Beträchtliche Komplikationen gab es keine. Die Frequenz der postoperativen Schmerzen war überraschend niedrig mit 15% am ersten postoperativen Tag, während nach einer Woche überhaupt von keinem Schmerz berichtet wurde. Kryohämorrhoidektomie ist eine einfache und schmerzlose Prozedur mit glattem postoperativen Verlauf und guten Resultaten, und sie ist für die Hämorrhoidenchirurgie mit kurzem Krankenhausaufenthalt bestens geeignet.
    Notes: Summary Fifty-three consecutive cases of second and third degree hemorrhoids were treated by cryosurgery. The follow-up time was 3 to 12 months, and a good result was obtained in 96%. The patients stayed overnight in the hospital. There were no major complications. The frequency of postoperative pain was surprisingly low: 15% on the first postoperative day, and not one instance of pain after one week. Cryohemorrhoidectomy is a simple and painleB procedure with a smooth postoperative course and good results, and it is very appropriate for short-stay hemorrhoid surgery.
    Type of Medium: Electronic Resource
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