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  • 1
    Electronic Resource
    Electronic Resource
    Lewis Acid-Promoted Diastereoselective Radical Cyclization Using Chiral .alpha.,.beta.-Unsaturated Esters (1994)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 116 (1994), S. 6455-6456 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00093a064
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Asymmetric acetalization: a simple method for the synthesis of chiral a-monosubstituted cyclopentanones (1993)
    s.l. : American Chemical Society
    The @journal of organic chemistry 58 (1993), S. 5870-5872 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00074a002
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Influence of ligation of the internal iliac veins on the venous plexuses around the sacrum (1998)
    Springer
    Journal of orthopaedic science 3 (1998), S. 264-271 
    Details
    ISSN: 1436-2023
    Keywords: Key words: total sacrectomy ; hemostasis ; venous pressure ; experimental study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: Excessive bleeding is a significant problem during total sacrectomy. Ligation of the internal iliac veins to control bleeding from the pelvic venous plexus has been reported to be mandatory. However, despite ligation of the internal iliac veins, excessive hemorrhage from the pelvic and epidural venous plexuses is often encountered. We postulated that ligation of the internal iliac veins increases blood loss during total sacrectomy and we investigated the influence of ligation of the internal iliac veins on the pelvic and epidural venous plexuses in white rabbits. We also investigated the influence of the animal's operative position on the epidural venous pressure. Venography was performed to study the differences in blood flow patterns before and after ligation of the internal iliac veins. Without ligation, contrast medium passed into the inferior vena cava, but not into the epidural venous plexus. The epidural venous plexus was contrast-filled when the internal iliac veins were ligated. The pressure in the internal iliac veins was increased with their ligation, and decreased with ligation of the abdominal aorta. The pressure was also decreased with intentional bleeding from the epidural venous plexus, and with changing the animal's position to headdown. Ligation of the internal iliac veins leads to congestion of the pelvic venous and epidural venous plexuses. Ligation of the internal iliac arteries and positioning the animal headdown were effective ways to resolve the congestion in these venous plexuses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007760050052
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Three-dimensional topographic analysis of spinal accessory motoneurons under chronic mechanical compression: an experimental study in the mouse (1997)
    Springer
    Journal of neurology 244 (1997), S. 222-229 
    Details
    ISSN: 1432-1459
    Keywords: Key words Spinal accessory nerve ; Motoneuron ; Three-dimensional topography ; Wheat germ agglutinin-horseradish peroxidase ; Tiptoe-walking Yoshimura (twy) mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated the effect of chronic mechanical compression of the cervical spinal cord on the number of spinal accessory motoneurons in 25 tiptoe-walking Yoshimura mice. The animals had calcified deposits in the atlantoaxial membrane at the C1–C2 vertebral level, compressing the spinal cord posterolaterally. Motoneurons of the spinal accessory nerve between C1 and C5 segments were labelled using wheat germ agglutinin-horseradish peroxidase (WGA-HRP) injected into the sternocleidomastoid muscles. The counted cells were processed into a three-dimensional computer display to analyse the cytoarchitectonic changes caused by external cord compression. The number of WGA-HRP-labelled spinal accessory motoneurons was significantly reduced on the affected side. The number of motoneurons in compromised C2 and C3 cord segments correlated linearly with the extent of mechanical compression, but no such relationship was present on the contralateral side. There was an increase in the number of WGA-HRP-labelled spinal accessory motoneurons in the medial cell pools of the anterior grey horn at a level most rostral to the compression, and in the ventrolateral cell pools at levels immediately rostral to the compression. Our findings suggest that the spinal accessory motoneurons translocate rostral to the area of external compression in order to avoid mechanical injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004150050076
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  • 5
    Electronic Resource
    Electronic Resource
    Quantitative analysis of the spinal cord motoneuron under chronic compression: an experimental observation in the mouse (1996)
    Springer
    Journal of neurology 243 (1996), S. 109-116 
    Details
    ISSN: 1432-1459
    Keywords: Spinal cord compression ; Motoneuron ; Topography ; Nissl stain ; Tiptoe-walking Yoshimura (twy) mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated quantitative changes in spinal cord motoneurons following chronic compression using a mouse model of cervical cord compression. Twenty-five tiptoe-walking Yoshimura (twy) mice with calcified mass lesions compressing the spinal cord posterolaterally at the C1–C2 vertebral levels were compared with five Institute of Cancer Research (ICR) mice that served as controls. Spinal cord motoneurons in the anterior grey horn between the C1 and C3 spinal cord segments were Nissl-stained and counted topographically and then analysed in relation to the extent of spinal cord compression. The number of motoneurons in C1–C3 spinal cord segments decreased significantly with a linear correlation with the transverse area of the spinal cord when the cord was compressed to 50–70% of control values. A significant reduction in the number of motoneurons occurred at the C2–C3 spinal cord segment compressed at the C1–C2 vertebral level. In contrast, at the level rostral to the C1 vertebra, the number of motoneurons increased significantly in proportion to the magnitude of compression. The current study demonstrates that a number of neurons, morphologically consistent with anterior horn cells, were observed at a rostral site absolutely free of external compression where no such cells normally exist.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02443999
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  • 6
    Electronic Resource
    Electronic Resource
    Determination and quantitative analysis of alkaloids in Aconitum japonicum by liquid chromatography atmospheric pressure chemical ionization mass spectrometry (1994)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 23 (1994), S. 97-102 
    Details
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometric method was useful for the simultaneous determination of aconitine-type alkaloids (jesaconitine, aconitine, mesaconitine, aljesaconitine A, aljesaconitine B, hokbusine A, deoxyjesaconitine, deoxyaconitine, hypaconitine, 14-anisoylaconine, 14-benzoylaconine, and 14-benzoylmesaconine) and other alkaloids (neoline, delcosine, 14-acetyldelcosine, kobusine, pseudokobusine, and lucidusculine found in Aconitum japonicum. These compounds were quite stable under the conditions used, and the protonated molecules or fragment ions characteristic of the molecule appeared as base peaks in the mass spectra and were used for selected ion monitoring. The method is linear over the range from 10 ng (50 ng; jesaconitine and neoline) to 10 μg of alkaloid per injection. The detection limits of aconitine-type alkaloids and neoline were ∼ 2-20 ng per injection.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200230209
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    Paper (German National Licenses)
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