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  • 1
    Electronic Resource
    Electronic Resource
    Eine Skala zur Messung von Beschwerden bei degenerativen Veränderungen der Halswirbelsäule (HWS) Hilfe zur Indikationsstellung und zur Evaluation des Operationserfolgs (1999)
    Springer
    Der Chirurg 70 (1999), S. 1364-1373 
    Details
    ISSN: 1433-0385
    Keywords: Key words: Diseases of the cervical spine ; Somatic symptoms ; Quality of life ; Quality assurance ; Orthopedic surgery. ; Schlüsselwörter: Erkrankungen der Halswirbelsäule (HWS) ; körperliche Symptome ; Lebensqualität ; Qualitätssicherung ; Orthopädische Chirurgie.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Eine Skala zur Messung von Beschwerden bei degenerativen Veränderungen der Halswirbelsäule (HWS) wird vorgestellt. Es werden 20 typische Symptome erfaßt, z. B. Nackenschmerzen, Gefühlsstörungen, Beweglichkeitseinschränkungen. Die Einschätzung erfolgt mittels einer 6-stufigen Skalierung („hatte ich nicht“ bis „hatte ich und belastete mich sehr“). Die HWS-Skala wurde bei drei Stichproben getestet: orthopädisch-chirurgische HWS-Patienten (n = 70), Poliklinik-Patienten mit überwiegend anderen orthopädischen Diagnosen (n = 104), gesunde Studenten (n = 100). Aus den Einzelsymptomen wurden vier Scores gebildet: Anzahl der Symptome, Gesamtbelastung, Funktionseinschränkung, Schmerz/psychische Beeinträchtigung. Statistische Analysen belegen deren hohe Reliabilität (Cronbachs Alpha = 0,85–0,95) und Validität (inhaltlich, konvergent, diskriminant). Die Skala differenziert sehr gut zwischen HWS-Patienten, Patienten mit anderen Diagnosen und Probanden einer gesunden Stichprobe, sowie zwischen erfolgreich und nicht erfolgreich operierten HWS-Patienten. Für Anwendungszwecke läßt sich die HWS-Skala in ein Lebensqualitätsprofil (LQ-Profil) einbauen. Auf diese Weise kann der LQ-Status individueller Patienten in einer graphisch sehr anschaulichen Form dargestellt werden.
    Notes: Summary. A scale for measuring symptoms related to degenerative diseases of the cervical spine is presented. Twenty typical symptoms are listed, e. g., neck pain, dysesthesia, and reduced mobility. Responses are assessed via a 6-point scaling (“did not have symptom”–“had symptom and suffered very strongly”.) The cervical spine scale was tested in three samples: patients having undergone cervical spine surgery (n = 70), patients with other orthopedic diagnoses (n = 104), and healthy students (n = 100). The single items of the scale were aggregated into four scores: total number of symptoms, degree of overall symptom distress, functional disability, and pain/psychological distress. Statistical analyses proved the high reliability (Cronbach's alpha = 0.85 to 0.95) and validity (content, convergent, discriminant) of all scores. The scale differs clearly between cervical spine patients, other orthopedic patients and healthy individuals, and between cervical spine patients with different subjective operative outcomes. For applied clinical purposes the cervical spine scale can be included in a quality of life profile (QL-profile); this allows for a readily understandable graphic depiction of individual patients' QL-status.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001040050796
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  • 2
    Electronic Resource
    Electronic Resource
    Cementless gustilo-kyle and BIAS total hip arthroplasty: 2- to 5-year results (1991)
    Springer
    Archives of orthopaedic and trauma surgery 110 (1991), S. 179-186 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We conducted extensive radiographic and clinical examination of 58 cementless total hip arthroplasties. Forty BIAS femoral stems had heads made of Co-base F 75 alloy and 18 Gustilo-Kyle femoral stems had Ti6A14V alloy heads. The cross-sectional geometry and location of the porous coating pads of the two stem types was identical, the BIAS component being slightly shorter. At the last follow-up, 27.8% of the Gustilo-Kyle femoral components and 2.5% of the BIAS femoral components were unstable. None of the acetabular components in the BIAS group as against 38.9% of the acetabular components in the Gustilo-Kyle group demonstrated wear of more than I mm. All unstable components which did not suffer intraoperative fracture had also acetabular wear of more than 1 mm. The only case with endosteal erosion was seen in a patient with an unstable implant displaying the most extensive wear. Nonparametric statistical analysis showed that the patients with Ti6A14V/polyethylene bearing surfaces had a statistically significantly higher extent of wear and a statistically significant higher incidence of femoral component loosening than patients with CrCoMo/polyethylene bearing surfaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00571055
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  • 3
    Electronic Resource
    Electronic Resource
    Recombinant and nonrecombinant factor XIII and its effect on bone ingrowth and strength of fixation (1997)
    Springer
    Archives of orthopaedic and trauma surgery 116 (1997), S. 239-243 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirty cylindrical, commercially pure, titanium fiber, porous-coated Ti6Al4V implants were inserted pressfit into the proximal humeral portion of 30 sheep humeri to determine the systemic effect of recombinant factor XIII and placenta-derived factor XIII concentrate on bone ingrowth and strength of fixation. For both the recombinant factor XIII and the factor XIII concentrate group, the volume of bone ingrowth and the strength of fixation were higher than for the control specimens. However, the difference was only significant for the factor XIII concentrate group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00393720
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  • 4
    Electronic Resource
    Electronic Resource
    Three- to five-year results with the cementless Harris-Galante acetabular component used in hybrid total hip arthroplasty (1992)
    Springer
    Archives of orthopaedic and trauma surgery 111 (1992), S. 142-147 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In this paper we present our 3- to 5-year results after hybrid total hip replacement using the cementless porous coated Harris-Galante acetabular component and the cemented Griss femoral component in 39 patients with 40 implantations. Postoperatively, mild to moderate pain was experienced by 16.1% of patients, mostly following hard activity. A slight to moderate limp occurred in 24.2%. All patients were able to walk more than 1000 m. Full-time use of support was required by 2.8%. The postoperative range of motion was increased in 93.9%. Radiographically, none of the acetabular or femoral components had to be classified as unstable. Only one acetabular component displayed complete (i.e., along all interface zones) radiolucency and was therefore classified as possibly unstable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00388088
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  • 5
    Electronic Resource
    Electronic Resource
    Recombinant and nonrecombinant factor XIII and its effect on bone ingrowth and strength of fixation (1997)
    Springer
    Archives of orthopaedic and trauma surgery 116 (1997), S. 239-243 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirty cylindrical, commercially pure, titanium fiber, porous-coated Ti6Al4V implants were inserted press-fit into the proximal humeral portion of 30 sheep humeri to determine the systemic effect of recombinant factor XIII and placenta-derived factor XIII concentrate on bone ingrowth and strength of fixation. For both the recombinant factor XIII and the factor XIII concentrate group, the volume of bone ingrowth and the strength of fixation were higher than for the control specimens. However, the difference was only significant for the factor XIII concentrate group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00393720
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  • 6
    Electronic Resource
    Electronic Resource
    Prevention of heterotopic bone formation after total hip arthroplasty: a prospective randomised study comparing postoperative radiation therapy with indomethacin medication (1999)
    Springer
    Archives of orthopaedic and trauma surgery 119 (1999), S. 296-302 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Heterotopic ossification (HO) after total hip arthroplasty is known to be a major complication with an impact on the functional outcome. Efforts have been made to prevent the occurrence of HO by means of either radiation therapy or pharmacotherapy. To date, there are no data available regarding the relative benefit of radiation versus medication with non-steroidal anti-inflammatory drugs. The objective of this study was to compare single-dose 600-cGy radiation therapy with indomethacin medication for their effect on the prevention of heterotopic bone formation after total hip arthroplasty. In all, 154 patients were included in the study. All patients underwent primary total hip arthroplasty due to osteoarthritis. Patients were randomly assigned to three different therapeutic groups. (a) The radiation group received a single radiation dose of 600 cGy between the 2nd and 4th postoperative day. (b) The indomethacin group received an oral application of indomethacin 2 × 50 mg per day from the 1st to 42nd postoperative day. (c) The control group received neither radiation nor indomethacin medication. There were significant group differences (P 〈 0.001). A least significant difference test (LSD) revealed that the mean of the control group was significantly different from that of the radiation and indomethacin groups. The 13 patients (8.4%) classified Brooker 3 or 4 were all in the control group. Again, this effect was statistically significant (chi-square, P 〈 0.001). In conclusion, this study demonstrated that both radiation and indomethacin therapy are effective in the prevention of postoperative HO. The choice for either one of the treatments has to be based on availability, contraindications, side-effects, practicability, standardisation and cost. Based on these considerations together with the results of this study, we currently use postoperative radiation with 600 cGy for all patients undergoing primary total hip arthroplasty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004020050414
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  • 7
    Electronic Resource
    Electronic Resource
    Standardized evaluation of long-term results after anterior lumbar interbody fusion (1996)
    Springer
    European spine journal 5 (1996), S. 299-307 
    Details
    ISSN: 1432-0932
    Keywords: Anterior lumbar fusion ; Follow-up studies ; Radiology ; Low back pain ; Outcome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A total of 113 patients, excluding those with tumor, spondylitis, and idiopathic scoliosis, underwent anterior lumbar interbody fusion (ALIF) with autologous iliac crest graft between 1984 and 1991 at our department. The proportion of these who were failed back patients was higher than that reported in the literature. Evaluation of functional outcome was feasible in 80 patients, utilizing Oswestry and Marburg scores, which were closely intercorrelated. The overall results yielded an improvement in the Oswestry score of 35.7 percentage points. A subset of 52 patients who were evaluated twice, showed the same results at an average of 6.6 years as they did at 2.3 years following surgery. Functional results showed a weak correlation with postoperative height loss of the intervertebral space. Influencing factors for the functional result were: postoperative compensation claim, age, and obesity. Of the professional people involved, 19.4% did not return to any occupation. Patients satisfied with the result had significantly greater functional improvement. Younger patients with additional dorsal distraction prior to ALIF for reduction of severe spondylolisthesis fared better than patients with ALIF alone. The rate of complications was low and did not contribute to the postoperative functional result. On the basis of these results further prospective studies have been designed and are currently underway.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304344
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  • 8
    Electronic Resource
    Electronic Resource
    Biocompatibility analysis of different biomaterials in human bone marrow cell cultures (1998)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 40 (1998), S. 301-306 
    Details
    ISSN: 0021-9304
    Keywords: biocompatibility ; biomaterials ; human bone marrow cell culture ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A cell culture system for biocompatibility testing of hip implant materials is described. Human bone marrow cells have been chosen because these cells are in direct contact with the biomaterial after implantation in situ. The sensitivity of this method is evaluated for materials which are already being used as implants in humans and animal, e.g., hydroxyapatite (HA) ceramic, pure titanium, and ultra-high-molecular-weight polyethylene (UHMWPE). As indicative parameters of biocompatibility primary cell adherence, cell number, cell proliferation, production of extracellular matrix, cell vitality, and cell differentiation are described. After 2 weeks in culture, obvious differences between the biomaterials with respect to the indicative parameters could be observed. Cell numbers were greatest on the HA specimens. In the case of titanium alloys, we observed a decreased number of cells. The production of extracellular matrix was high for the HA ceramics but reduced for titanium specimens. The polymers allowed only a few adherent cells and showed no signs of extracellular matrix production. The results can be correlated astonishingly well to animal experiments and clinical experiences. Therefore, we suggest that this cell culture system seems to be a useful tool for biocompatibility testing of bone implantation materials. It also helps reduce animal experiments. With the help of flow cytophotometry, we analyzed the influence of biomaterials on large numbers of cells with respect to differentiation. There were similar populations of T cells and monocytes on all specimens tested. Extended B-cell and granulocyte populations, however, were observed with titanium and UHMWPE. Most osteocalcin-containing cells adhered to the HA ceramics. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 40, 301-306, 1998.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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