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  • 1
    Electronic Resource
    Electronic Resource
    Sarcocystis in Muscles of Raccoons (Procyon lotor L.) (1987)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 34 (1987), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Sarcocysts of Sarcocystis sp. were found in 26 (50%) of 52 raccoons (Procyon lotor) from Ohio, Pennsylvania, Florida, and Maryland. Although only 4 (7.7%) of 52 cardiac muscle specimens were found to contain sarcocysts, 25% to 36.5% of tongue, diaphragm, masseter muscle, and esophagus specimens were found infected. By light microscopy, sarcocyst walls were 〈3 μm thick and had no conspicuous projections; interior septa were indistinct. By transmission electron microscopy, sarcocyst walls had short (mean = 2.7 μm), villus-like protrusions; thin septa were seen within the sarcocysts. The raccoon may be an intermediate host for a Sarcocystis sp. that completes its life cycle in an unidentified, wild carnivore.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1987.tb03211.x
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  • 2
    Electronic Resource
    Electronic Resource
    The Regulatory Effect of Histamine on the in Vitro Synthesis of IgE (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 41 (1986), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effect of histamine and its H1 and H2 antagonists, chlorpheniramine and cimetidine, on the in vitro, PWM-induced, synthesis of IgG and IgE was studied. Histamine had no effect, and cimetidine had a slight inhibitory action. In contrast, chlorpheniramine induced marked suppression of both IgE and IgG synthesis. This effect could not be attributed to drug-induced cytotoxicity. These results suggest that the modulatory effect of histamine on antibody production involves predominantly H, receptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1986.tb00270.x
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  • 3
    Electronic Resource
    Electronic Resource
    The Regulatory Effect of Macrophages on the in Vitro Synthesis of IgE (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 40 (1985), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of indomethacin or macrophage-depletion on the in vitro unstimulated and pokeweed mitogen (PWM)-induced synthesis of IgG and IgE were compared. The effect on the unstimulated synthesis of IgG and IgE was similar, namely, no effect due to indomethacin and enhancement due to macrophage depletion. In contrast, the effect on PWM-induced synthesis was dissimilar. Macrophage depletion enhanced IgG but inhibited IgE production. The effect of indomethacin paralleled that of macrophage depletion suggesting the involvement of prostaglandins. It seems that the regulatory effect of macrophages is different in the IgE system compared with the IgG system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1985.tb00225.x
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  • 4
    Electronic Resource
    Electronic Resource
    Additions and Corrections - Oxotrimolybdenum(IV) Alkoxides, Mo3(μ3·O)(μ3·OR)(μ2·OR)3(OR)6 (R = CH(CH3)2 and CH2C(CH3)3). Synthetic Considerations (1982)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 104 (1982), S. 2084-2084 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00371a600
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  • 5
    Electronic Resource
    Electronic Resource
    Oxotrimolybdenum(IV) alkoxides: Mo3(.mu.3-O)(.mu.3-OR)(.mu.2-OR)3(OR)6, where R = isopropyl and neopentyl. Synthetic considerations (1981)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 103 (1981), S. 5967-5968 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00409a080
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  • 6
    Electronic Resource
    Electronic Resource
    Metal alkoxides - models for metal oxides. 1. Preparations and structures of hexadecaalkoxytetratungsten compounds, W4(OR)16, where R = Me and Et, and octaoxotetraisopropoxytetrapyridinotetramolybdenum, Mo4(O)4(.mu.-O)2(.mu.3-O)2(O-i-Pr)2(.mu.-O-i-Pr)2(py)4 (1981)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 103 (1981), S. 6093-6099 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00410a018
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  • 7
    Electronic Resource
    Electronic Resource
    CONTRACTURES PRODUCED BY CARBAMATE ANTICHOLINESTERASES IN BOVINE TRACHEAL SMOOTH MUSCLE (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 9 (1982), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. In isolated strips of bovine tracheal muscle the carbamate anticholinesterases, neostigmine and eserine caused similar, slowly-developing, sustained spasms which were concentration-related in the range 10−7-10−4 mol/l; these spasms could be abolished either by withdrawing the anticholinesterase or by addition of atropine (5 × 10−7 mol/l).2. Depletion of tissue stores of acetylcholine using hemicholinium-3 with or without electrical stimulation rendered the muscle unresponsive to neostigmine (10−6 mol/l). Responses to acetylcholine itself were not impaired.3. A low concentration of neostigmine (10−8 mol/l) did not cause spasm but enhanced the contractile response of bovine trachealis to acetylcholine, carbachol and histamine. This concentration of neostigmine also increased the muscle's contraction upon exposure to a high-potassium solution, even in the presence of atropine (5 × 10−7 mol/l).4. It is concluded that neostigmine and eserine cause spasm not only by preventing breakdown of endogenously released acetylcholine but also by stimulating release of acetylcholine from nerve terminals and by a non-specific enhancement of muscle contraction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1982.tb00831.x
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  • 8
    Electronic Resource
    Electronic Resource
    RELAXATION FOLLOWING CONTRACTION IN TONICALLY CONTRACTED SMOOTH MUSCLE FROM THE BOVINE TRACHEA (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 12 (1985), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Isometric tension was recorded from strips of bovine tracheal smooth muscle in which the tone had been artificially raised by agonist drugs such as histamine and carbachol.2. Application of exogenous acetylcholine produced a biphasic response consisting of an initial contraction followed by a more prolonged relaxation before tone was restored to normal.3. Atropine blocked both components of the biphasic response to exogenous acetylcholine.4. Tetrodotoxin blocked neither phase of the response to exogenous acetylcholine even though a similar biphasic response to electrical stimulation was severely disrupted.5. Application of exogenous substance P produced a biphasic response of similar magnitude and form to that produced by acetylcholine.6. Application of exogenous histamine (tone raised by carbachol) also produced a biphasic response although higher concentrations were required to produce a relaxation of equal magnitude to that produced by acetylcholine.7. It is concluded that the inhibitory component of the biphasic response to exogenous acetylcholine occurs as a non-specific sequel to contraction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1985.tb00896.x
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  • 9
    Electronic Resource
    Electronic Resource
    THE CONTRACTILE RESPONSE OF SMOOTH MUSCLE TO IMMERSION IN HYPERTONIC SOLUTIONS (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 7 (1980), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Strips of bovine tracheal muscle and rabbit aorta produced sustained contractions on perfusion with Krebs solution made twice normal strength by addition of sucrose. The contractures were relaxed on return to normal Krebs solution.2. Similar contractures were produced by tracheal muscle strips in Krebs solutions made twice normal strength by addition of galactose, glucose or NaCl whereas urea caused only a transient contraction.3. In twice normal strength Krebs solution (sucrose added) the basal tension of rat portal vein and guinea-pig taenia coli was increased. Spontaneous mechanical activity was maintained, but the frequency of contractions was reduced.4. The hypertonic contracture of bovine trachea in twice normal strength Krebs solution (sucrose added) was reduced by 15% by omission of Ca from the bathing fluid (01 mmol/1 EGTA added). Severe Ca depeletion, by prolonged washing in Ca-free Krebs with 12.5 mmol/1 EGTA and Carbachol added, resulted in a 77% reduction in the hypertonic contracture.5. In twice normal Krebs solution (sucrose added), the hypertonic contracture was partially relaxed by isoprenaline (4 × 10−6 mol/1); the contractile response to carbachol was reduced; the contractile response to high-K Krebs solution was maintained.6. Atropine (5 × 10−7 mol/1) abolished the contractile response to carbachol, but had no effect on the hypertonic contracture.7. It is suggested that the contraction of bovine tracheal strips in hypertonic solutions is mainly due to activation of the contractile myofilaments rather than simple cell shrinkage. Hypertonic solutions may also interfere with some steps in the excitation-contraction coupling sequence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1980.tb00056.x
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  • 10
    Electronic Resource
    Electronic Resource
    Interaction between drugs and potassium-rich solutions in producing contraction in bovine tracheal smooth muscle: studies in normal and calcium-depleted tissues (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 2 (1975), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The contracture normally induced in isolated bovine tracheal smooth muscle by potassium-rich solution was abolished by removal of the extracellular calcium. The contraction returned when calcium was added to the solution in a concentration greater than 0·05 mmol/l.2. The amplitudes of the potassium-contracture, and of the contractile responses to histamine and acetylcholine in normal physiological solutions, declined at low temperatures (15–25°C). If drugs were added during the plateau phase of the potassium contracture, the extra tension developed above the contracture did not change with temperature.3. Calcium-depletion reduced the responses to drugs, and repeated application of the drugs in calcium-free solution produced progressively smaller contractions, suggesting that an intracellular store of calcium was being used up.4. Depolarization of calcium-depleted tracheal muscle by high-K+ solution without calcium produced responses to drugs which were larger than those in sodium-based calcium-free solutions. There was no potentiation in a solution in which sodium was replaced by sucrose, suggesting that potassium was not acting simply by replacing the sodium.5. It is suggested that depolarization of the membrane by potassium makes available a fraction of bound calcium which was not available in calcium-free sodium-based solution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1975.tb01861.x
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