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  • 1
    Electronic Resource
    Electronic Resource
    Tendon properties in relation to muscular activity and physical training (2003)
    Oxford, UK : Munksgaard International Publishers
    Scandinavian journal of medicine & science in sports 13 (2003), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: Movement is caused by force transmission from contracting muscles to bone via tendon. The collagen structure of tendon is organized in a very hierarchical manner. The collagen fibril is considered the basic force-transmitting unit of tendon, and it is embedded in a hydrophilic extracellular matrix of proteoglycans, glycoproteins and glycosaminoglycans. It has recently been shown in human peritendinous tissue is more metabolically active in response to activity than previously thought, although it remains to be established, if the level of activity influences affects fibril diameter and/or total tendon cross-sectional area. Moreover, it cannot be unequivocally concluded that tendon adaptation to physical activity is one of a quantitative and/or qualitative nature. The currently available information is almost exclusively obtained from animal data, however, techniques such as microdialysis for tendon metabolism and ultrasound combined with MRI for tendon mechanical properties has already provided information on human tendon behavior, and is likely to further add to our understanding of how tendon adapt to physical activity. This review will address the structure and function of tendon, and the current knowledge of how tendons respond to activity with respect to biomechanical properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0838.2003.00308.x
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  • 2
    Electronic Resource
    Electronic Resource
    Timing of post-exercise protein intake is important for muscle hypertrophy with resistance training in elderly humans (2002)
    Oxford, UK : Munksgaard International Publishers
    Scandinavian journal of medicine & science in sports 12 (2002), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: (1) Age-associated loss of skeletal muscle mass and strength can partly be counteracted by resistance training, causing a net synthesis of muscular proteins. Protein synthesis is influenced synergistically by post-exercise amino acid supplementation, but the importance of the timing of protein intake remains unresolved. (2) The study investigated the importance of immediate (P0) or delayed (P2) intake of an oral protein supplement upon muscle hypertrophy and strength over a period of resistance training in elderly males. (3) Thirteen men (age 74 ± 1 years; body mass index (BMI), 25 ± 1 kg m− 2 (means ± SEM)) completed a 12-week resistance training program (three times per week) receiving oral protein in liquid form (10 g protein, 7 g carbohydrate, 3 g fat) immediately after (P0) or 2 h after (P2) each training session. Muscle hypertrophy was evaluated by magnetic resonance imaging (MRI) and from muscle biopsies and muscle strength was determined using dynamic and isokinetic strength measurements. Body composition was determined from dual-energy X-ray absorptiometry (DEXA) and food records were obtained over 4 days. The plasma insulin response to protein supplementation was also determined. (4) In response to training, the cross-sectional area of m. quadriceps femoris (54.6 ± 0.5–58.3 ± 0.5 cm2) and mean fiber area (4047 ± 320–5019 ± 615 μ m2) increased in the P0 group, whereas no significant increase was observed in P2. For P0 both dynamic and isokinetic strength increased, by 46 and 15%, respectively (P 〈 0.05), whereas P2 only improved in dynamic strength, by 36% (P 〈 0.05). No differences in glucose or insulin response were observed between protein intake at 0 and 2 h post-exercise. (5) We conclude that early intake of an oral protein supplement after resistance training is important for the development of hypertrophy in skeletal muscle of elderly men in response to resistance training.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0838.2002.120111_2.x
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  • 3
    Electronic Resource
    Electronic Resource
    Viscoelastic stress relaxation during static stretch in human skeletal muscle in the absence of EMG activity (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 6 (1996), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The present study sought to investigate the role of EMG activity during passive static stretch. EMG and passive resistance were measured during static stretching of human skeletal muscle in eight neurologically intact control subjects and six spinal cord-injured (SCI) subjects with complete motor loss. Resistance to stretch offered by the hamstring muscles during passive knee extension was defined as passive torque (Nm). The knee was passively extended at 5o/s to a predetermined final position, where it remained stationary for 90 s (static phase) while force and integrated EMG of the hamstring muscle were recorded. EMG was sampled for frequency domain analysis in a second stretch maneuver in five control and three SCI subjects. There was a decline in passive torque in the 90-s static phase for both control and SCI subjects, P〈0.05. Although peak passive torque was greater in control subjects, P〈0.05, there was no difference in time-dependent passive torque response between control (33%) and SCI (38%) subjects. Initial and final 5-s IEMG ranged from 1.8 to 3.4 μ V.s and did not change during a stretch or differ between control and SCI subjects. Frequency domain analysis yielded similar results in both groups, with an equal energy distribution in all harmonics, indicative of ‘white noise’. The present data demonstrate that no measurable EMG activity was detected in either group during the static stretch maneuver. Therefore, the decline in resistance to static stretch was a viscoelastic stress relaxation response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0838.1996.tb00101.x
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  • 4
    Electronic Resource
    Electronic Resource
    Viscoelastic response to repeated static stretching in the human hamstring muscle (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 5 (1995), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The purpose of this study was (1) to evaluate the reproducibility of a new method of measuring passive resistance to stretch in the human hamstring muscle group, in vivo, using a test re-test protocol and 2) to examine the effect of repeated stretches. Passive resistance offered by the hamstring muscle group during knee extension was measured in 10 subjects as knee flexion moment (Nm) using a KinCom dynamometer. The knee was passively extended at 5 deg/s to the final position where it remained stationary for 90 s (static phase). EMG of the hamstring muscle was also measured. The test re-test protocol included 2 tests (tests 1 and 2) administered 1 h apart. On a separate occasion 5 consecutive static stretches were administered (stretches 1–5) separted by 30 s. Stretch 6 was administered one hour after stretch 5. In the static phase passive resistance did not differ between test 1 and test 2. Resistance declined in both tests 1 and 2, whereas EMG activity remained unchanged. The decline in resistance was significant up to 45 s. For the repeated stretches there was an effect of time (90 s) and stretch (1–5) with a significant interaction i.e., resistance diminished with stretches, and the 90-s decline was less as more stretches were performed. Passive resistance in stretch 6 was lower than in stretch 1. The present study has demonstrated a reliable method for studying resistance to stretch of the human hamstring muscle group. A viscoelastic response of the human hamstring muscle was shown. With 5 repeated stretches, resistance to stretch diminished and each stretch exibited a viscoelastic response, albeit less with each subsequent stretch. The effect of 5 repeated stretches was significant 1 h later.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0838.1995.tb00056.x
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  • 5
    Electronic Resource
    Electronic Resource
    Load-displacement properties of the human triceps surae aponeurosis and tendon in runners and non-runners (2002)
    Oxford, UK : Munksgaard International Publishers
    Scandinavian journal of medicine & science in sports 12 (2002), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The load-displacement and stress–strain characteristics of the human triceps surae tendon and aponeurosis, in vivo, was examined during graded maximal voluntary plantarflexion efforts in runners who trained 80 km/ week or more and age-matched non-runners. Synchronous real-time ultrasonography of triceps surae tendon and aponeurosis displacement, electromyography of the gastrocnemius, soleus and dorsiflexor muscles, and joint angular rotation were obtained. Tendon cross-sectional area and ankle joint moment arm were obtained from magnetic resonance imaging. Tensile tendon force was calculated from the joint moments and tendon moment arm and stress was obtained by dividing force by cross-sectional area. Strain was obtained from the displacements normalized to tendon length. Antagonist coactivation and small amounts of ankle joint rotation significantly affected tensile tendon force and aponeurosis and tendon displacement, respectively (P 〈 0.01). Plantarflexion moment was similar in runners (138 ± 27 Nm, mean ± SEM) and non-runners (142 ± 17 Nm). Tendon moment arm was alike in non-runner (58.3 ± 0.2 mm) and runners (55.1 ± 0.1 mm). Similarly, there was no difference in tendon tensile force between runners (2633 ± 465 N) and non-runners (2556 ± 401 N). The cross-sectional area of the Achilles tendon was larger in runners (95 ± 3 mm2) than non-runners (73 ± 3 mm2) (P 〈 0.01). The load-deformation data yielded similar stiffness (runners 306 ± 61 N/mm, non-runners 319 ± 42 N/mm). The maximal strain and stress was 4.9 ± 0.8% and 38.2 ± 9.8 MPa in non-runners and 4.1 ± 0.8% and 26.3 ± 5.1 MPa in runners. The larger tendon cross-sectional area in trained runners suggests that chronic exposure to repetitive loading has resulted in a tissue adaptation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0838.2002.120205.x
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  • 6
    Electronic Resource
    Electronic Resource
    The effect of short-term strength training on human skeletal muscle: the importance of physiologically elevated hormone levels (2001)
    Copenhagen : Munksgaard International Publishers
    Scandinavian journal of medicine & science in sports 11 (2001), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The effect of strength training and endogenously elevated hormone levels (plasma testosterone, growth hormone (GH) and cortisol) was studied in 16 young untrained males, divided into an arm only training group, A, and a leg plus arm training group, LA, in order to increase circulating levels of anabolic hormones. Both groups performed the same one-sided arm training for 9 weeks, twice a week. Group A trained only one arm (AT), the contralateral arm serving as control (AC), whereas group LA additionally trained their legs following the training of the one arm (LAT), with the contralateral arm serving as control (LAC). In spite of the attempt to match the two groups, the initial isometric arm strength was 20–25% lower for group LA compared to group A (significant for the arm to be trained). Isometric strength increased significantly in LAT and LAC by 37% and 10%, respectively, while the 9% and 2% increases in AT and AC, respectively, remained insignificant. Isokinetic strength increased at one out of three velocities tested for the trained arm relative to the untrained arm in both group A and group LA (P〈0.05). Functional strength increased significantly by 20% in LAT, 18% in LAC, 19% in AT, and 17% in AC. Hormonal responses were monitored during the first and last training sessions. Resting hormone levels remained unchanged for both groups. However, during the first training session plasma testosterone as well as plasma cortisol increased significantly in group LA but not in group A. Plasma GH rose in all exercise tests, except during the last test in group LA, but was significantly higher in group LA than in group A in the first training session. In conclusion, a larger relative increase in isometric strength was found in the group having the highest hormonal response. However, due to the initial difference in isometric strength caution must be taken with the interpretation of this finding, which may only indicate a possible link between anabolic hormones and muscle strength with training.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0838.2001.110606.x
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  • 7
    Electronic Resource
    Electronic Resource
    Exercise and organ transplantation (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 9 (1999), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: Life-saving treatment of disease by organ transplantation has become increasingly important. Annually over 35 000 transplantations of vital organs are carried out world-wide and the demand for knowledge regarding exercise in daily life for transplant recipients is growing. The present review describes whole-body and organ reactions to both acute exercise and regular physical training in persons who have undergone heart, lung, liver, kidney, pancreas or bone marrow transplantation. In response to acute exercise, the majority of cardiovascular, hormonal and metabolic changes are maintained after transplantation. However, in heart transplant recipients organ denervation reduces the speed of heart rate increase in response to exercise. Furthermore, lack of sympathetic nerves to transplanted organs impairs the normal insulin and renin responses to exercise in pancreas and kidney transplant recipients, respectively. In contrast, surgical removal of sympathetic liver nerves does not inhibit hepatic glucose production during exercise, and denervation of the lungs does not impair the ability to increase ventilation during physical exertion. Most studies show that physical training results in an improved endurance and strength capacity in almost all groups of transplant recipients, which is of importance for their daily life. With a little precaution, organ transplant recipients can perform exercise and physical training and obtain effects comparable with those achieved in the healthy population of similar age.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0838.1999.tb00200.x
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  • 8
    Electronic Resource
    Electronic Resource
    Lactate/H+ transport in skeletal muscle from spinal-cord-injured patients (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 8 (1998), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: In order to evaluate the effect of prolonged muscle inactivity on sarcolemmal lactate/H+ transport in humans, the lactate/H+ transport capacity was determined in the thigh muscle of spinal-cord-injured (SCI) individuals. The lactate transport rate was measured in sarcolemmal giant vesicles produced by collagenase treatment of muscle biopsies obtained from the vastus lateralis muscle. Six SCI subjects with total loss of motor and sensory functions of their lower limbs participated in the study. The duration of the injury ranged from 2 to 15 years. The total lactate transport rate in the muscle of SCI patients was 46.5±2.6 pmol · cm−2· s−1 (mean±SEM), which corresponds to a 17% lower (P〈0.05) transport rate than that found in healthy, untrained subjects. The estimated carriermediated lactate/H+ transport capacity was approximately 26% lower in the SCI patients than in healthy, untrained subjects. The observed muscle lactate/H+ transport capacity of SCI individuals is in accordance with a positive correlation between the capacity of the lactate/H+ transporters and the percentage occurrence of slow-twitch fibres in a muscle, although there seems to be a wide range of transport capacities within each fibre type. The present results show that the sarcolemmal lactate/H+ transport capacity is lower in SCI individuals than in normally physically active subjects, which indicates that prolonged muscle inactivity reduces the lactate/H+ transport capacity of human muscle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0838.1998.tb00175.x
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  • 9
    Electronic Resource
    Electronic Resource
    Growth hormone and connective tissue in exercise (2005)
    Oxford, UK : Munksgaard International Publishers
    Scandinavian journal of medicine & science in sports 15 (2005), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: Over the last few years, growth hormone (GH) has become increasingly popular as doping within different sports. However, the precise mechanisms behind the ergogenic (performance enhancing) effects of GH in athletes are still being debated. Besides a well-documented stimulatory effect of GH on carbohydrate and fatty acid metabolism, and a possible anabolic effect on myofibrillar muscle protein, we suggest a role for GH as an anabolic agent in connective tissue in human skeletal muscle and tendon. Given the importance of the connective tissue for the function of skeletal muscle and tendon, a strengthening effect of GH on connective tissue could fit with the ergogenic effect of GH experienced by athletes.This review examines the endogenous secretion of GH and its mediators in relation to exercise. Furthermore, we consider the effect of endogenous GH and administered recombinant human GH (rhGH) on both myofibrillar and connective tissue protein synthesis, thus offering an alternative explanation for the ergogenic effect of GH. Finally, we suggest a possible therapeutic role for rhGH in clinical management of the frequently suffered injuries in the connective tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0838.2005.00455.x
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  • 10
    Electronic Resource
    Electronic Resource
    The effect of supervised rehabilitation on strength, postural sway, position sense and re-injury risk after acute ankle ligament sprain (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 9 (1999), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: The effect of an early rehabilitation program, including postural training, on ankle joint function after an ankle ligament sprain was investigated prospectively. Ninety-two subjects, matched for age, sex, and level of sports activity, were randomized to a control or training group. All subject received the same standard information regarding early ankle mobilization. In addition, the training group participated in supervised physical therapy rehabilitation (1 h. twice weekly) with emphasis on balance training. Postural sway, position sense and isometric ankle strength were measured 6 weeks and 4 months after the injury, and at 12 months re-injury data were obtained. In the training group, there was a significant difference between the injured and uninjured side for plantar flexion (P〈0.01), eversion (P〈0.01) and inversion (P〈0.05), but not for dorsiflexion at 6 weeks. In the control group, there was a significant difference between the injured and uninjured side for plantar flexion (P〈0.01), eversion (P〈0.01), inversion (P〈0.01), and dorsiflexion (P〈0.05) at 6 weeks. Postural sway, but not position sense, differed between the injured and uninjured side in both groups (P〈0.01) at 6 weeks. The side-to-side percent differences were similar in both groups for all variables (P〉0.05) at 6 weeks, and there were no side-to-side differences at 4 months in either group. In the control group, 11/38 (29%) suffered a re-injury. while this number was only 2/29 (7%)) in the training group (P〈0.05). These data showed that an ankle injury resulted in reduced ankle strength and postural control at 6 weeks, but that these variables had normalized at 4 months, independent of the supervised rehabilitation. However, the findings also demonstrated that supervised rehabilitation may reduce the number of re-injuries, and therefore may play a role in injury prevention.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0838.1999.tb00217.x
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