Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Synthese und Pharmakologie einiger 3,5-di-und trisubstituierter Hydantoine (1961)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 4 (1961), S. 231-258 
    Details
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jm50018a003
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Coronary reactive hyperaemia and coronary dilator action of adenosine during normal respiration and hypercapnic acidosis in the dog (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 2 (1975), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The effects of hypercapnic acidosis on coronary conductance, the coronary dilator effect of adenosine administered into the coronary artery and the reactive hyperaemic response after short and long periods of coronary artery occlusion were investigated in thoracotomized dogs.2. The coronary conductance was positively correlated to the arterial PCO2 and negatively correlated to the arterial pH.3. During control periods the reactive hyperaemic response increased with increasing duration of coronary artery occlusion, whereas the percentage repayment of the deficit remained unchanged.4. The reactive hyperaemic response after short periods of coronary artery occlusion (up to ten beats) was diminished during hypercapnic acidosis. This decrease may be explained on the basis of an increased tissue PO2 or a decreased relative change in tissue pH.5. The dilator effect of adenosine administered into the coronary artery was enhanced during hypercapnic acidosis.6. The reactive hyperaemic response after long periods of coronary artery occlusion (above fifteen to twenty beats) was also enhanced during hypercapnic acidosis, and may be a result of myocardial adenosine formation during coronary artery occlusion.7. The findings indicate that coronary blood flow after coronary artery occlusions may be primarily regulated by local pH changes in the coronary vessel cells. Additional dilatation after longer coronary artery occlusion may result from the release of adenosine by the hypoxic myocardium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1975.tb01845.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effects of X-irradiation on Papillary Muscle of the Cat (1960)
    [s.l.] : Nature Publishing Group
    Nature 188 (1960), S. 413-415 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig 1 Ordinate : Average percentage changes of membrane resting potential, action potential, rate of rise, 20, 50, and 90 per cent repolarization time and mechanical tension compared with the average control values of all experiments performed (100 per cent). Abscissa Time in min. post-irradiation. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/188413a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Papierchromatographische auftrennung und bestimmung von kreatin und kreatinin im plasma
    Amsterdam : Elsevier
    Clinica Chimica Acta 8 (1963), S. 960-965 
    Details
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(63)90021-4
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Isolation and quantitative determination of 3-O-methyladrenaline and 3-O-methylnoradrenaline in urine
    Amsterdam : Elsevier
    Clinica Chimica Acta 6 (1961), S. 851-860 
    Details
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(61)90174-7
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Über das Triäthylendiamin (Bicyclo-[2,2,2]-1,4-diaza-octan) (1951)
    Springer
    Monatshefte für Chemie 82 (1951), S. 880-900 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00905126
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Über die Synthese neuer Acylpiperazine. I (1954)
    Springer
    Monatshefte für Chemie 85 (1954), S. 1208-1214 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Zusammenfassung Im Rahmen von Untersuchungen, welchen Einfluß der Ersatz der Estergruppe durch die Säureamidgruppe auf die pharmakologische Wirkung ausübt, wurde eine Reihe von Mono-acylpiperazinen hergestellt. Die verhältnismäßig leicht zugänglichen Monoalkylpiperazine enthalten neben dem acylierbaren sekundären Stickstoff eine für die Herstellung wasserlöslicher Präparate durch Bildung von Salzen und quartären Salzen notwendige tertiäre Aminogruppe. Als Acylreste wurden in vorliegender Arbeit substituierte Phenylessigsäuren herangezogen, da solche, von allem die Diphenylessigsäure, bei der Veresterung mit Aminoalkoholen wertvolle Spasmolytika liefern.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00899903
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Über die Synthese neuer Acylpiperazine. II (1954)
    Springer
    Monatshefte für Chemie 85 (1954), S. 1215-1222 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Zusammenfassung In Fortsetzung unserer Untersuchungen, wie sich der Ersatz der Estergruppe durch die Säureamidgruppe auf die pharmakologischen Eigenschaften auswirkt, wurden Monoalkylpiperazine mit Diphenylchloracetylchlorid, o,o′-Dichlor-diphenyl-chloracetylchlorid, p,p′-Dimethoxy-diphenyl-chloracetylchlorid und endlich mit Diphenylenchloracetylchlorid acyliert und in den erhaltenen Produkten das Chlor des Chloracetylrestes durch Hydrolyse und Alkoholyse in OH, OCH3, OC2H5 sowie OC3H7 verwandelt. Von den entstandenen Basen wurden zur pharmakologischen Untersuchung Salze und quartäre Salze hergestellt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00899904
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Die Wirkung der Sulfationen auf das Membranpotential der isoliert durchströmten Säugetiermuskulatur (1957)
    Springer
    Cellular and molecular life sciences 13 (1957), S. 445-447 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Electrical potential measurements of membrane resting and action potentials were made by means of electrolyte-filled glass micro-electrodes on single fibres of the musculus gracilis of the cat using a perfused hind-limb preparationin situ. The release of potassium from muscle and the tension developed by the gastrocnemius muscle were simultaneously recorded. The normal resting potential in our series was 91.7 mV (s.d. ± 6.7 mV). Partial replacement of the chloride by sulfate in the perfusion fluid led to (a) potassium release from the perfused hind-limb, (b) reversible contracture of the gastrocnemius muscle, (c) depression of the membrane resting potential which was proportional to the degree of replacement of chloride by sulfate in the perfusion fluid and (d) to the occurrence of volleys of spontaneous fibrillation potentials some of which had the shape of damped oscillations. These findings are similar to those observed after treatment with veratrine and are interpreted to be due to (1) increase in sodium permeability and (2) disturbance of the Donnan equilibrium for chloride ions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02157243
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Freisetzung von Kalium aus denerviertem und innerviertem Skelettmuskel durch Acetylcholin (1955)
    Springer
    Cellular and molecular life sciences 11 (1955), S. 197-199 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Both hind limbs of cats (one being normally innervated, the other 8–12 days after denervation) were perfused and the quantities of potassium liberated from the two limbs in response to intraarterial injections of varying amounts of acetylcholine were compared by collecting the venous outflow from both sides separately; considerably larger quantities of potassium were found to be liberated from the denervated than from the innervated muscle after equal doses of ACH; the threshold dose of ACH for eliciting a measurable liberation of potassium being much lower on the denervated side. The dose response relation between injected ACH and potassium-liberation is of a different nature for innervated and denervated muscle. The results obtained are compatible with expectations derived from the “short circuit theory” of the transmitter action on the neuromuscular endplate (Fatt andKatz). The reasons of the difference in the dose relations for the innervated and denervated muscle are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02161317
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...