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  • 1
    Electronic Resource
    Electronic Resource
    221. Transhepatische Endlosdrainage nach Goetze-Dick bei Stenosen der intra- und extrahepatischen Gallenwege (1978)
    Springer
    Langenbeck's archives of surgery 347 (1978), S. 695-695 
    Details
    ISSN: 1435-2451
    Keywords: Stenosis, bile duct ; Transhepatic endless drain ; Gallengangsstenosen ; transhepatische Endlosdrainage nach Goetze-Dick
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bericht über 49 Fälle von intra- und extrahepatischen Stenosen der Gallenwege (1970–1977), bei denen durch eine transhepatische Endlosdrainage nach Goetze-Dick der Galleabfluß wieder hergestellt wurde. Hauptindikation ist ein Verschlußikterus durch inoperable Tumoren der Gallenblase (21 Fälle), der Gallengänge (12 Fälle) und des Pankreas (8 Fälle). In 5 Fällen wurde eine benigne intrahepatisch gelegene Stenose mit Verschlußikterus durch die Endlosdrainage nach Dick beseitigt. Auf Indikationsstellung, Früh- und Spätkomplikationen sowie auf die postoperative Nachsorge wird näher eingegangen.
    Notes: Summary A report is presented on 49 cases of intra- and extrahepatic stenosis of the bile ducts (1970–1977), in which bile drainage was effected by a transhepatic endless drain according to the method of Goetze-Dick. The main indication is obstructive jaundice caused by inoperable tumors of the gall bladder (21 cases), the bile ducts (12 cases), and the pancreatic head (8 cases). In 5 cases a benign intrahepatic stenosis with obstructive jaundice was removed by an endless drain. The indication for this operation, the early and late complications, and postoperative care are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01579513
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  • 2
    Electronic Resource
    Electronic Resource
    Morphological changes in osteosarcoma after chemotherapy — COSS 80 (1983)
    Springer
    Journal of cancer research and clinical oncology 106 (1983), S. 32-37 
    Details
    ISSN: 1432-1335
    Keywords: Osteosarcoma ; Chemotherapy ; Imprint cytology ; Tumor-regression ; Undecalcified sections
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty-five osteosarcomas were investigated by special methods such as preparation of undecalcified bone tumor tissue, imprint cytology, histochemistry, and quantitative analysis. The morphological regression grades and their relation to chemotherapy are reported by Salzer-Kuntschik et al. (1983). The results presented demonstrate that smaller osteosarcomas respond more favorably than larger tumors. The function of bone-tumor cells, e.g., osteoid production, trabecular tumor bone formation, and mineralization, seems to be more important for the sensitivity to chemotherapy than the cell polymorphism. The estimation of bone-tumor morphology in at least two total areas of the bone tumor is essential in borderline cases (grade III/grade IV). Imprint cytology is very helpful for rapid estimation of the effect of therapy and the demonstration of cellular polymorphism. At the moment, we are not able to determine the effect of chemotherapy from the first biopsy before starting chemotherapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00625049
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  • 3
    Electronic Resource
    Electronic Resource
    Nuclear polymorphism in osteosarcomas as a prognostic factor for the effect of chemotherapy (1985)
    Springer
    Virchows Archiv 405 (1985), S. 215-223 
    Details
    ISSN: 1432-2307
    Keywords: Osteosarcoma ; Chemotherapy ; Quantitative Caryometry ; Morphometry ; Tumour regression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A current strategy for osteosarcoma treatment is neo-adjuvant chemotherapy prior to the resection of the tumour. It appears that some tumours respond very well to the cytostatic therapy, while others show little or no effect. It is desirable to be able predict the response of the tumour before starting chemotherapy. 16 biopsy specimens from patients with osteosarcoma who had been treated according to the protocol of the study COSS-80 and COSS-82 were examined. 100 tumour cells from each biopsy have been measured by an electronic interactive image analysis system (IBAS II; Kontron/ ZEISS). After completion of chemotherapy en bloc resection of the tumour was performed. The entire surgical specimen was completely examined at two levels by means of undecalcified sections, and assigned a grade for the effect of chemotherapy analogous to the grading of Salzer-Kuntschik et al. (1983). The quantitative analysis of tumour cell nuclei revealed two different patterns of nuclear sizes, which were correlated significantly with the chemotherapy response (P〈0.002). Tumour cell nuclei of well responders were significantly larger and showed a greater variance in size (mean value 66 + 41 µm2), than those of poor responders (mean value 38 + 18 µm2). We conclude from our results that quantitative analysis and classification of nuclear size of osteosarcoma cells may be useful for predicting chemotherapy response in patients with osteosarcoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00704373
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  • 4
    Electronic Resource
    Electronic Resource
    316. Operativer Verschluß großer Bauchwandhernien nach Dick (1979)
    Springer
    Langenbeck's archives of surgery 349 (1979), S. 633-634 
    Details
    ISSN: 1435-2451
    Keywords: Abdominal hernias ; Bauchwandhernie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Dargestellt werden Indikation, operative Technik und Nachsorge bei großen Bauchwandhernien. Das dargestellte OP-Verfahren ist geeignet zur Korrektur von Narbenhernien, Rectusdiastasen, großen Nabelhernien. Es wird eingegangen auf die Art des Nahtmaterials, die Präparation und Technik der Defektüberbrückung. Das Thema wird abgehandelt mit Text, Röntgenbildern, OP-Fotos, OP-Skizzen.
    Notes: Summary Indications, surgical technique and aftercare of large abdominal hernias are outlined. The surgical technique presented is suitable for correction of large and small umbilical hernias and repair of diastasis recti abdominis. Suture material, preparation and bridging the defect are discussed. The subject is treated by text, roentgenograms, photos and sketches of the operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01729777
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  • 5
    Electronic Resource
    Electronic Resource
    327. Das sogenannte Begleitlipom bei der Hiatushernie (1980)
    Springer
    Langenbeck's archives of surgery 352 (1980), S. 621-621 
    Details
    ISSN: 1435-2451
    Keywords: Hiatal hernia ; Lipoma ; Prophylaxis of recurrence ; Hiathushernie ; Begleitlipom ; Rezidivprophylaxe
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 198 Hiatushernienoperationen wurde in 52 % eine Fettgewebshyperplasie im Retrogastralraum, am Hisschen Winkel gefunden, die in den Hiatus oesophagi hineinreichen kann. Sie könnte den Wegbereiter der Hiatushernie darstellen. Bei der Versorgung der Hiatushernie sollte das ≫Lipom≪ abgetragen und der Stiel in die Nähte beim Aufbau des Hisschen Winkel eingeknüpft werden, dazu eine Einengung der Hiatusschenkel und Fundo-Gastropexie zur Verhinderung des Rezidivs.
    Notes: Summary In 52 % of 198 operations of hiatal hernia we found a hyperplasia of fatty tissue in the retrogastric space and in the area of His's angle. This hyperplastic fatty tissue extends in the esophageal hiatus and could act as the precursor of hiatal hernia. In addition to the common surgical treatment of hiatal hernia with a narrowing of the esophageal hiatus and esophagofundopexy, the ‘lipoma’ should be resected and the base should be fixed by sutures within His's angle in order to prevent a recurrence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01292292
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