Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    THE EFFECT OF THE MENOPAUSE ON THE L-LACTATE-NICOTINAMIDE-ADENINE DINUCLEOTIDE OXIDOREDUCTASE ACTIVITY IN VAGINAL ASPIRATES (1980)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 87 (1980), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Lactate dehydrogenase (L-Iactate-NAD+ oxidoreductase; EC 1.1.1.27) activity has been assayed in saline extracts of vaginal aspirates obtained from patients attending a Well Woman Clinic and for whom exfoliative cytology was shown to be unequivocally normal. The majority (76 per cent) of premenopausal patients gave aspirate extracts containing less than 25 m units of enzyme while 71 per cent of postmenopausal patients gave aspirate extracts containing more than 50 m units of enzyme. This difference in distribution of activities was highly significant (P = 〈0.001). Analysis of the isoenzyme distribution showed that aspirates from postmenopausal patients contained a lower proportion of isoenzyme LDH-5 (P 〈0.01) and the M subunit (P 〈0.03) and a higher proportion of isoenzymes LDH-3 (P 〈0.001) and LDH-4 (P 〈0.01). There was no significant difference between the social class distributions of the pre- and postmenopausal patients. Lactate dehydrogenase activity was not related to social class or patients' multiparity. No difference in the distribution of enzyme activities was found between those premenopausal patients in the proliferative phase of the menstrual cycle, those in the secretory phase and those receiving hormone therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1980.tb04426.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Cyclic GMP in urine to monitor the response of ovarian cancer to therapy (1982)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 89 (1982), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Guanosine 3′:5′-phosphate (cyclic GMP) in urine has been used to monitor the response of patients with ovarian cancer to treatment. Changes in the cyclic GMP level appear to correlate well with clinical status in that the disappearance of clinically detectable tumour is associated with a drop in the level whereas a tumour recurrence is associated with an elevation. Serially measured cyclic GMP is valuable for detecting a recurrence of tumour growth in patients in clinical remission and can predate any clinical signs by as much as 10 months. In patients who show no response to treatment, cyclic GMP levels in urine are elevated in the majority of specimens collected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1982.tb05105.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    THE EFFECT OF CARCINOMA OF THE CERVIX ON THE L-LACTATE-NICOTINAMIDE-ADENINEDINUCLEOTIDE OXIDOREDUCTASE ACTIVITY IN VAGINAL ASPIRATES (1981)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 88 (1981), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Lactate dehydrogenase (L-lactate-NAD+ oxidoreductase; EC 1. 1. 1. 27) has been assayed in saline extracts of vaginal aspirates obtained from patients with carcinoma in situ and from patients with clinically detectable invasive carcinoma of the cervix. Taking premenopausal and postmenopausal patients separately, significant differences were found between the aspirate lactate dehydrogenase activities obtained from patients with carcinoma in situ and the activities obtained from patients with invasive carcinoma; generally higher activities were obtained from the latter. With the exception of postmenopausal patients with carcinoma in situ, aspirate enzyme activities obtained from both groups of patients were significantly different from those obtained from normal women. Significantly higher lactate dehydrogenase activity was found in aspirates from patients for whom histology showed the presence of an adenocarcinoma or certain highly malignant cell types. Treatment by radium insertion usually resulted in a fall in total lactate dehydrogenase activity. Significant differences between patient groups were found for the proportions of single lactate dehydrogenase isoenzymes in a few instances but no significant difference in overall isoenzyme distribution was found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1981.tb00934.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Centrifugal Ultra-filtration (1950)
    [s.l.] : Nature Publishing Group
    Nature 165 (1950), S. 530-531 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In order to overcome the difficulty, we originally tried standardized flat disk-shaped 'Gradocol' membranes, under high pressures. Pressures as high as 40 atmo. failed to give a reasonable rate of filtration with a 1 in 4 dilution of blood or plasma in water. An alternative form of apparatus using ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/165530b0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Starch-gel Electrophoresis of Animal Sera (1957)
    [s.l.] : Nature Publishing Group
    Nature 180 (1957), S. 1366-1367 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The differences between the species are well illustrated. In common with Ashton we have not actually identified the protein bands in different species. We have, however, run human and various animal sera concurrently on the same gel. A typical picture of such a gel with dog serum can be seen in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1801366a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Effect of Analogues on the Uptake of Vitamin B 12 by the Intact Rat (1957)
    [s.l.] : Nature Publishing Group
    Nature 180 (1957), S. 1197-1198 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The analogues available to us were pseudovitamin B12, a mixture of the monoethylamides, desdimethyl B12 and vitamin B12 lactone (Fig. 1). Pseudovitamin B12 contains adenine in place of the 5 : 6 dimethyl -benziminazole of the vitamin molecule. The mixture of ethylamides consists of each of the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1801197a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    The in vitro effect of aprotinin upon spleen cells from normal and tumour-bearing mice exposed to PPD and tumour cells (1980)
    Springer
    Cellular and molecular life sciences 36 (1980), S. 247-249 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A protinin (Trasylol) is shown to enhance the response of spleen cells from normal and tumour bearing mice to PPD and tumour cells. This enhancement is greater in the tumour-bearing mice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01953761
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Modification by Crude Histones of Gene Activity for Lactate Dehydrogenase (1969)
    [s.l.] : Nature Publishing Group
    Nature 224 (1969), S. 71-73 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In embryonic chick brain organ cultures low concentrations of crude histone from calf thymus and chicken liver cause an inductive response in LDH activity, whereas at higher concentrations the response is repressive2. We have studied the effect of crude histone extracts on the LDH isoenzyme pattern ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/224071a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Fluoroacetate and Cyanocobalamin Absorption in the Rat (1964)
    [s.l.] : Nature Publishing Group
    Nature 201 (1964), S. 400-401 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Since fluoroacetate had no effect on the absorption of labelled coenzyme B12 it was concluded that the enzymatic conversion of cyanocobalamin to coenzyme B12 was an essential factor in the absorption of the former compound across the small intestine and that this conversion could be part of an ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/201400a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...