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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 173 (1990), S. 265-271 
    ISSN: 0006-291X
    Keywords: [abr] ACE; peptidyl dipeptidase A,E.C.3.4.15.1 (angiotensin-converting ; [abr] ANP; atrial natriuretic peptide ; [abr] BNP; brain natriuretic peptide ; [abr] E-24.11; endopeptidase E.C.3.4.24.11. ; [abr] IodoGen; 1,3,4,6-Tetrachloro-3a,6a-diphenylglycouril ; [abr] TFA; trifluoroacetic acid
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 173 (1990), S. 265-271 
    ISSN: 0006-291X
    Keywords: [abr] ACE; peptidyl dipeptidase A,E.C.3.4.15.1 (angiotensin-converting ; [abr] ANP; atrial natriuretic peptide ; [abr] BNP; brain natriuretic peptide ; [abr] E-24.11; endopeptidase E.C.3.4.24.11. ; [abr] IodoGen; 1,3,4,6-Tetrachloro-3a,6a-diphenylglycouril ; [abr] TFA; trifluoroacetic acid
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Cryobiology 21 (1984), S. 687-688 
    ISSN: 0011-2240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part 42 (1991), S. 103-104 
    ISSN: 0883-2889
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 35 (1979), S. 1129-1130 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A simple and non-destructive method for monitoring the dilution rate during continuous blood sampling is described. When the dilution rate is not constant, the proposed method based on electrical resistivity measurement provides a correction factor for further analysis.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'analyse rétrospective de 22 cas d'insulinomes pancréatiques colligés par les auteurs dans leur service leur a permis d'apprécier la valeur diagnostique des différentes méthodes d'exploration pré-opératoires et per opératoires. Dans 18 malades, les insulinomes uniques ont été localisés dans 55.5% des cas par l'artériographie sélective, dans 64% des cas par le cathétérisme transhépatique avec prélèvement étagé de sang veineux, et seulement dans 11% des cas par l'ultfasonographie et la tomodensitométrie. La combinaison de l'artériographie sélective et du cathétérisme transhepatique permit de définir le siège de la tumeur dans 83% des cas. La palpation chirurgicale, l'ultrasonographie au cours de l'intervention, le dosage peropératoire du glucose sanguin permirent dans tous les cas de découvrir une tumeur unique. Lorsque les insulinomes sont multiples les diverses méthodes pré-opératoires d'exploration ne sont pas fiables. Dans 4 cas d'insulinomes multiples les différentes explorations preoperatoires permirent de découvrir seulement 8 (28%) tumeurs sur un total de 28 existantes. On ne peut se fier à la palpation pour les decouvrir. Seuls l'échographie peropératoire et le dosage peropératoire du glucose sanguin décèlèrenttoutes les tumeurs multiples (le diamétre de la plus petite tumeur était de 4 mm). Ces 2 méthodes d'exploration opératoire constituent actuellement les procédés de choix pour mettre en évidence les petits insulinomes pancréatiques.
    Abstract: Resumen Se ha hecho la determinación del valor diagnóstico de diversos procedimientos de localización pre- e intraoperatoria mediante el anâlisis retrospectivo de 22 casos de insulinoma pancreáticos operados en nuestro centra médico. En los 18 pacientes, los insulinomas solitarios pudieron ser localizados por arteriografía selectiva (AS) en 55.5% de los casos, por cateterismo transhepático para muestreo venoso esplénico (MVET) en 64% de los casos, pero por ultrasonografía (US) y tomografía computadorizada (TC) apenas en 11% de los casos. La combinación de AS y MVET logró la localización preoperatoria del tumor en 83% de los casos. La palpación intraoperatoria, la ultrasonografía, y la monitoría de la glicemia logró la localización del tumor en la totalidad de los otros casos que poseían un tumor único. Cuando los insulinomas eran multiples, los diversos exámenes preoperatorios demostraron no ser confiables. En los 4 casos con insulinomas múltiples, varios exámenes (AS, US, TC, MVET) lograron localizar solo 8 (28%) tumores entre 28. La palpación intraoperatoria fue igualmente inadecuada. Sólo la US intraoperatoria y la monitoría continuada de la glicemia lograron la localización de latotalidad de los tumores multiples, siendo 4 mm el diámetro del más pequeño de los tumores. Estos 2 tipos de examen intraoperatorio representan actualmente los procedimientos de elección para detectar pequenos insulinomas pancreáticos.
    Notes: Abstract From a retrospective analysis of 22 cases of pancreatic insulinoma operated in our center, we have determined the predictive value of various pre- and intraoperative localization procedures. In 18 patients, solitary insulinomas were localized by selective arteriography (SA) in 55.5% of cases, by transhepatic catheterization with pancreatic venous sampling (THVS) in 64% of cases, but by ultrasonography (US) and computed tomography (CT) in only 11% of cases. The combination of SA and THVS allowed the preoperative localization of the tumor in 83% of cases. Intraoperative palpation, ultrasonography, and blood glucose monitoring localized a single tumor in all cases. When the insulinomas were multiple, the various preoperative investigations were not reliable. In the 4 cases of multiple insulinoma, various investigations (SA, US, CT, THVS) localized only 8 (28%) tumors of 28. Intraoperative palpation was also unreliable. Only intraoperative ultrasonography and continuous blood glucose monitoring localizeall multiple tumors (the diameter of the smallest tumor was 4 mm). These 2 intraoperative investigations are now the procedures of choice for the detection of small pancreatic insulinomas.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 186 (1986), S. 133-139 
    ISSN: 1433-8580
    Keywords: Flow ; Thermodilution ; Inferior vena cava ; Dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Simple methods for measuring percutaneously blood flow in veins characterized by a large oscillatory component of flow are lacking. Therefore, a thermodilution technique with a constant infusion rate was used for the measurement of inferior vena cava flow in anesthetized dogs. The accuracy of the method was studied both in an artificial circuit and in in vivo experiments. The thermal catheter was introduced upstream in a flow of water ranging from 50 to 1,200 ml/min produced in an artificial circuit maintained at 37°C. With a volume of cold injectate of 43 ml/20s, the correlation between the values obtained by direct measurement and by thermodilution technique was highly significant (r = 0.993;n = 37) with a slope practically equal to 1.0 (Y = 1.03 X + 2.42). With the thermal catheter introduced through the jugular vein and an electromagnetic flowmeter probe placed around the exposed vessel, volumetric flows were registered in the subhepatic vena cava, infrarenal vena cava, as well as renal and iliac veins of eight dogs. Comparison of the values obtained by the two techniques yielded a regression equation of Y = 0.96 X + 34.31 with a correlation coefficientr = 0.943 (range 50–1,000 ml/min;n = 40). The continuous injection method was as accurate at low flows as at high. Qualitatively, thermodilution curves were comparable to electromagnetic flowmeter curves, reproducing instantaneously the cyclic respiratory variations. The method is thus particularly suitable for use in those veins in which there is a large oscillatory component of flow.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1433-8580
    Keywords: Venous surgery ; Mesothelium ; Fibrinolytic activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Autogenous mesothelium was used as venous substitute in ten dogs. Patches of mesothelium of three different origins were grafted into the anterior wall of the common iliac veins (CIV): peritoneum taken from and including the posterior rectus sheath (PRS), simple peritoneum (P) and mesentery (M). Animals were killed after 2, 4, 8, and 16 days and after 3 months. The segments of CIV, including the patches, were removed for study. On light microscopy, the PRS grafts showed a normal mesothelium but marked submesothelial fibrosis. The M and P grafts showed normal mesothelium and only mild fibrous thickening. On scanning electron microscopy, there was a perfect continuity of the mesothelial cells and the normal endothelium at the suture line. In the center of the graft, the cells had become elongated along the axis of blood flow. Fibrinolytic activity (FA) was measured by a standardized fibrin plate technique and quantitated in tissue activator units per gram of tissue (TAU/g). The mean FA of iliac vein specimens was 1101.7 ± 133.3TAU/g (mean±SEM). The mean FA determined before grafting for each kind of mesothelium was the following: PRS = 418.8±26.9TAU/g; P = 873.0±107.1TAU/g; M = 1142.3 ± 91.4TAU/g where only PRS showed values significantly lower than iliac vein mean FA (P 〈 0.001). Postoperatively, the mesothelial FA, after an initial reduction, increased on day 4 and reached values significantly higher than the control values (1445.7±204.1TAU/g tissue vs 853.1±62.3 TAU/g tissue;P 〈 0.001). The morphologic adaptation and the maintained fibrinolytic activity of mesothelial cells in the venous system suggest that they can replace endothelium.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2277
    Keywords: Atrial natriuretic factor, in kidney transplantation ; Renal ischemia, atrial natriuretic factor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Because of the deleterious effects of acute tubular necrosis (ATN) after kidney transplantation, the search for new and effective means of protecting the kidneys from ischemic or nephrotoxic injuries continues. The beneficial effects of hyperhydration with mannitol or furosemide infusions in renal allograft recipients have now been well documented. The recent discovery by De Bold and coworkers that hypervolemia (by atrial distension) induces the release of atrial natriuretic factor (ANF) suggests an important physiopathological, and perhaps therapeutic, role for this natriuretic peptide in kidney transplantation. In addition to providing an overview of the current knowledge about ANF and its effects on both intact and ischemically injured kidneys, the physiological role of ANF in various situations, similar to those found in kidney transplantation, is analyzed. The effects of ANF on arachidonic acid metabolites and on the nephrotoxic side effects of cyclosporin are also reported. If the results of the preliminary experimental studies appear to be effective, further prospective clinical trials must be carried out to confirm them.
    Type of Medium: Electronic Resource
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