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  • 1
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 100 (1993), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 100 (1993), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 99 (1992), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Serum progesterone, oestradiol, human chorionic gonadotrophin (hCG) and human placental lactogen (hPL) were determined serially throughout 27 pregnancies in insulin-dependent diabetic patients from Newcastle (UK), 15 such patients from Stockholm (Sweden) and in 69 normal women having uncomplicated pregnancies. Mean progesterone, oestradiol and hCG concentrations were somewhat higher in the diabetic women during the third trimester but hPL values were not different from normal. The increased hormone concentrations did not relate to the increased birthweights or placental weights in the diabetic women. It is suggested that the usual physiological endocrine changes during normal pregnancy are relatively undisturbed by insulin-dependent diabetes or the degree of diabetes control achieved.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 96 (1989), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Serial measurements of serum progesterone, oestradiol, human chorionic gonadotrophin (hCG) and human placental lactogen (hPL) have been determined in 33 women experiencing early pregnancy failure and compared with the values of the same hormones in 72 healthy women having uncomplicated pregnancies. Steroid production by the corpus luteum seemed similar in both groups up to 6 weeks gestation but thereafter placental steroidogenesis was not evident in those women in whom spontaneous pregnancy losses occurred. Placental production of the two protein hormones, hCG and hPL, did take place, and whereas the circulating levels were not as high as in normal pregnancies, levels did usually increase before clinical evidence of miscarriage occurred. hCG was not a sensitive discriminator of subsequent failure. In these women there were no significant hormone differences between those with evidence of a fetus and those without.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 92 (1985), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Summary. Human pregnancy may induce changes in the sensitivity of the cardiovascular system to endogenous catecholamines. This was investigated in multigravid women with little likelihood of unsuspected vascular disease. Txe responses of blood pressure, pulse rate, plasma noradrenaline and adrenaline to a change in posture from semi-decumbency to standing were assessed in six normotensive women at 36 weeks gestation and in six non-pregnant control subjects. Standing for 10 min caused a surge in blood pressure, pulse rate and plasma noradrenaline in non-pregnant women. The pregnant women, whose basal levels of noradrenaline were higher than those in non-pregnant women, showed a slower noradrenergic response to postural change, and this response had less effect upon the cardiovascular indices. Blood pressure dropped immediately on standing and pulse rate remained unaffected throughout. It is suggested that some women may maintain a non-pregnant level of pressor sensitivity during pregnancy and thereby become hypertensive.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 88 (1981), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Haematological indices were studied serially in 33 healthy women, at one week before delivery, during the first six days of the puerperium, at six weeks and six months post partum. Red cell count, haemoglobin concentration and haematocrit decreased during the first four days of the puerperium; haemoglobin concentrations up to 3·5 g/dl less than pre-delivery values were recorded in the absence of clinical postpartum haemorrhage. The second puerperal day haemoglobin concentration correlates most closely with the six week postpartum value. A leucocytosis of greater than 20 × 109/1 was found on the first puerperal day in 15 per cent of the women studied.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 82 (1975), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The concentration of glucose and insulin was estimated in 854 samples of umbilical cord blood plasma and 503 concurrently collected maternal blood samples. The mean cord insulin concentration, excluding all infants born to known diabetic mothers, was 7 μU./ml., but the distribution was skewed with 10 per cent of infants having a value of 12 μU./ml. or more. The giving of intravenous sugar-coating fluids to the mother during labour tended to exaggerate the skewness rather than move the whole distribution to the right. Babies born by the vaginal route, whatever the presentation or method of delivery, had slightly lower mean insulin values than those born by Caesarean section. It thus seems unlikely that “stress” is a factor causing high cord insulin values at birth. Other data concerning maternal-fetal glucose and insulin relations are discussed.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 79 (1972), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: One hundred and thirty-one conceptuses obtained at hysterotomy between 12 and 22 weeks were examined to establish the relation between amniotic fluid volume and fetal weight, and between the sodium and urea content of amniotic fluid and that of maternal and fetal plasma. In 37 of the fetuses bladder urine was obtained for the estimation of sodium and urea. In 44, samples of abdominal skin were obtained and the movement of sodium and water through it was studied in an Ussing-type cell; ion movement across the amnion and chorion was also measured. Up to mid-pregnancy amniotic fluid volume was closely related to fetal weight, and the sodium and urea content of amniotic fluid volume was closely related to fetal weight, and the sodium and urea content of amniotic fluid was more closely related to that in fetal plasma than to that in maternal plasma.Data showing that the fetal kidney is capable of reabsorbing sodium and concentrating urea even before mid-pregnancy is presented. Intermittent addition of fetal urine may explain why the sodium content of amniotic fluid is slightly below that of plasma.Fetal skin was shown to be freely permeable to sodium and water in early pregnancy but the rate of diffusion slowed as mid-pregnancy was reached with evidence of a block at the external skin surface. No electrical potentials were detected and neither vasopressin nor angiotensin affected the rate of diffusion. Fetal membranes, at least in the experimental conditions used, were also freely permeable to sodium and water.The evidence supports the hypothesis that, in the first half of pregnancy, amniotic fluid may be an extension of the fetal extracellular fluid space.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 10
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 78 (1971), S. 0 
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Samples of amniotic fluid and of maternal blood were obtained at abdominal hysterotomy, by amniocentesis from patients with rhesus iso-immunization and at surgical induction of labour. In 135 women whose pregnancies were beyond mid-term, the menstrual dates were accurately known.The characteristics of the cells in amniotic fluid, after staining with haematoxylin and eosin, enabled three stages of gestation—under 32 weeks, 33–36, and 37 weeks and over—to be distinguished with reasonable certainty.The samples of amniotic fluid and blood were examined biochemically. In amniotic fluid after mid-term, osmolality and sodium concentrations fell with gestational age, while levels of urea and creatinine rose. Though the levels of these factors in maternal blood remain fairly constant throughout gestation, it was possible to relate differences between levels in blood and in amniotic fluid to gestational age. Equations showing these relationships are presented.The results were not influenced by the severity of haemolytic disease in the fetuses.
    Materialart: Digitale Medien
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