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  • 1
    Electronic Resource
    Electronic Resource
    Successful treatment of recurrent cerebral empyema and brain abscesses with Imipenem (1987)
    Springer
    European journal of clinical microbiology & infectious diseases 6 (1987), S. 578-580 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Imipenem was successfully used to treat a case of subdural empyema complicated by multiple cerebral abscesses, in which surgery and therapy with other antibiotics had previously failed. Imipenem concentrations in serum, cerebrospinal fluid and the cerebral abscess were much higher than the MICs for the infecting organisms, qualifying this antibiotic as an effective option in therapy of suppurative intracranial infections.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02014252
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  • 2
    Electronic Resource
    Electronic Resource
    Comparison of seven phenotyping methods forCandida albicans (1995)
    Springer
    European journal of epidemiology 11 (1995), S. 221-224 
    Details
    ISSN: 1573-7284
    Keywords: Candida albicans ; Candidiasis ; Mycological typing techniques ; Vulvovaginal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Seven different phenotyping methods for strain differentiation ofCandida albicans (auxono-typing, enzymotyping, resistotyping, Phongpaichit's morphotyping, Hunter's morphotyping and Odds and Abbott's biotyping method — 1980 and 1983 versions) were compared on a single population of 94 strains. 77.6% of the strains belonged to auxono-typing 1, 59.6% to enzymotyping A, 34% to resistotyping B and 30.8% to BC, 40.4% to Phongpaichit's morphotyping 000,000 and 40.4% to Hunter's morphotyping ‘No fringe/Smooth surface’. Using biotyping systems (1980 and 1983 versions), the most frequent biotypes were 145 (29.8%) and 147 (31.9%) respectively. The Discriminatory Index of Hunter and Gaston was employed to carry out comparisons among the different systems. The best discriminatory results, although far from ideal, were found using Phongpaichit's morphotyping (DI=0.827) and Odds and Abbott's method (DI=0.815 and 0.831 — 1980 and 1983 versions). A good discriminatory result was also found using Hunter's morphotyping method together with the biotyping of Odds and Abbott (1983 version). These approximated the ideal (DI=0.950) and showed minimal difficulty in interpretation. The proposed combined method revealed high discrimination among the vulvovaginal strains, and suggested the absence of transmissible pathogenic strains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01719492
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  • 3
    Electronic Resource
    Electronic Resource
    Plasmid typing of Shigella sonnei epidemic strains and molecular relationship of their R-plasmids (1988)
    Springer
    European journal of epidemiology 4 (1988), S. 158-163 
    Details
    ISSN: 1573-7284
    Keywords: S. sonnei ; Plasmid typing ; Epidemic ; Plasmid relationship
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We conducted a surveillance program on epidemic and/or endemic Shigella strains in Asturias (Spain), their frequency and dispersion in our community, and their R-plasmids. We analyzed initial isolates of Shigella sonnei from two epidemic outbreaks using antibiotic resistance patterns and plasmid profile analysis as epidemiological markers. We found that the 2 outbreaks were caused by different S. sonnei strains, which respectively carried one and two R-plasmids together with other plasmids. The molecular relationship among these and three other R-plasmids from two S. sonnei strains isolated during a previous outbreak, were studied by restriction enzyme analysis and DNA-DNA hybridizations. We were able to establish different levels of relationship among the six R-plasmids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00144744
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  • 4
    Electronic Resource
    Electronic Resource
    Endarteritis and mycotic aortic aneurysm caused by an oral strain ofActinobacillus actinomycetemcomitans (1998)
    Springer
    European journal of clinical microbiology & infectious diseases 17 (1998), S. 104-107 
    Details
    ISSN: 1435-4373
    Keywords: Actinobacillus actinomycetemcomitans ; Endarteritis ; Aneurysm ; Clonal identity ; Periodontitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Actinobacillus actinomycetemcomitans was isolated from blood cultures of a 33-year-old febrile patient with a previously undiagnosed coarctation of the aorta. Subgingival samples from diseased periodontal pockets revealed the presence ofA. actinomycetemcomitans. An infected (mycotic) aortic aneurysm and endarteritis were diagnosed and surgically treated. The identity of blood and oral clinical isolates ofA. actinomycetemcomitans was supported by genetic analysis, including finger-printing by restriction fragment length polymorphism, ribotyping, and random amplified polymorphic DNA; biotyping; and antibiogram typing. These data strongly suggest that the periodontal pockets were the primary source ofA. actinomycetemcomitans endarteritis in this case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01682165
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  • 5
    Electronic Resource
    Electronic Resource
    Epidemiological Study of Streptococcus pneumoniae Carriers in Healthy Primary-School Children (1999)
    Springer
    European journal of clinical microbiology & infectious diseases 18 (1999), S. 771-776 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  To obtain information on the Streptococcus pneumoniae carrier state in Spanish children, 332 healthy 6-year-old children from nine primary schools in northern Spain were screened. Thirty-six percent of the children had positive cultures yielding 128 strains. Seventy-one strains belonged to 14 serogroup/serotypes, the most frequent being 19, 23, 3, 24 and 11. Fifty-seven strains were non-typeable. The identification of strains with equivocal results was confirmed at species level by means of hybridisation with a specific probe, pneumolysin-mediated agglutination and a pathogenicity test in mice. Sixty-four percent of strains showed resistance to penicillin, 22% of these also being resistant to cefotaxime. More than 40% of the strains were resistant to trimethoprim-sulfamethoxazole, tetracycline and erythromycin. Twenty percent of the erythromycin-resistant strains were susceptible to clindamycin. Two strains were resistant to rifampicin and one strain was resistant to ofloxacin. All strains were susceptible to vancomycin. Previous antibiotic administration and having siblings under the age of 2 years correlated with the carriage of pneumococcus. There was no correlation with the carriage of antibiotic-resistant strains, or a record of previous infections, previous hospital admissions or having relatives with chronic respiratory disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100960050399
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  • 6
    Electronic Resource
    Electronic Resource
    Characteristics ofPseudomonas aeruginosa strains causing septicemia in a Spanish hospital 1981–1990 (1992)
    Springer
    European journal of clinical microbiology & infectious diseases 11 (1992), S. 698-703 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The epidemiological and biochemical characteristics ofPseudomonas aeruginosa strains causing septicemia in a Spanish hospital over a ten-year period (1981–1990) were analyzed. A total of 207 episodes, corresponding to 0.7 episodes per 1,000 inpatients and 3.2 % of the total number of episodes of septicemia, were registered. Males were more often affected than females (rate 3.2:1). The respiratory (24.6 %) and urinary (21.2 %) tracts were the main portals of entry, while haematologic and solid tumours (15.4 %) were the most frequent underlying diseases. More than 86 % of the strains were susceptible to ceftazidime, mezlocillin, piperacillin and amikacin. Seventy strains were subjected to typing and analysis of virulence factors. Serotypes O:6, O:11 and O:2 could be considered endemic (each present in more than 11.4 % of strains). Pyocin typing, antibiotyping and resistotyping were preferred as secondary typing methods to phage typing and plasmid profile analysis. The combination of methods revealed a large diversity of strains although some cluster predominated. More than 80 % of the strains produced several exoenzymes, possessed pyoverdin and showed haemolytic activity, and all except one showed serum resistance. All strains were susceptible to silver and more than 80 % to mercury and boron, but all were resistant to iodine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01989973
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  • 7
    Electronic Resource
    Electronic Resource
    Endarteritis and Mycotic Aortic Aneurysm caused by an Oral Strain of Actinobacillus actinomycetemcomitans (1998)
    Springer
    European journal of clinical microbiology & infectious diseases 17 (1998), S. 104-107 
    Details
    ISSN: 1435-4373
    Keywords: Key words Actinobacillus actinomycetemcomitans ; Endarteritis ; Aneurysm ; Clonal identity ; Periodontitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Actinobacillus actinomycetemcomitans was isolated from blood cultures of a 33-year-old febrile patient with a previously undiagnosed coarctation of the aorta. Subgingival samples from diseased periodontal pockets revealed the presence of A. actinomycetemcomitans. An infected (mycotic) aortic aneurysm and endarteritis were diagnosed and surgically treated. The identity of blood and oral clinical isolates of A. actinomycetemcomitans was supported by genetic analysis, including fingerprinting by restriction fragment length polymorphism, ribotyping, and random amplified polymorphic DNA; biotyping; and antibiogram typing. These data strongly suggest that the periodontal pockets were the primary source of A. actinomycetemcomitans endarteritis in this case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01682165
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Survey ofEscherichia coli septicemia over a six-year period (1992)
    Springer
    European journal of clinical microbiology & infectious diseases 11 (1992), S. 110-117 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Escherichia coli was the most frequent species isolated from blood cultures in the Hospital Covadonga of Oviedo (Spain) over a six-year period (474 episodes, 15.3 % of the total septicemias and 2.7 episodes per 1,000 patients).Escherichia coli strains were susceptible in 〉95 % of episodes to cefoxitin, cefotaxime, gentamicin, tobramicin and amikacin. In a series of 72 episodes, microbiological features and host factors were studied. No endemic strains were found. Type 1 fimbria was detected in 73.6% of strains and P-fimbriae in 12.5 %, without correlation between P-fimbria and urinary infection; 84.7 % of the strains were resistant to decomplement human serum; 61.1 % produced aerobactin and 20.8 % were hemolytic. Factors such as age, hospital location, metastatic focus and surgical treatment were significantly correlated with morbidity and mortality. The global mortality rate was 18 %, and in 8.3 % of cases was directly associated with septicemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01967061
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  • 9
    Electronic Resource
    Electronic Resource
    Susceptibility of Candida Species Isolated from Female Prostitutes with Vulvovaginitis to Antifungal Agents and Boric Acid (1999)
    Springer
    European journal of clinical microbiology & infectious diseases 18 (1999), S. 59-61 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The aim of this study was to determine the antifungal susceptibility of 108 Candida albicans and 23 Candida glabrata isolates obtained from female prostitutes with vulvovaginitis, a population for which available data is limited. Amphotericin B, flucytosine, and fluconazole were tested by broth microdilution, and boric acid was tested by the agar dilution method. The susceptibility patterns found in this population were the same as those in the general population. Candida glabrata required greater concentrations of boric acid for inhibition in vitro than did Candida albicans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100960050227
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