ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
The purpose of this study was to examine the neuroanatomical pattern of cells which concentrate 3H-estradiol in the brain and pituitary of a carnivore, the mink, Mustela vison. In addition, since the mink has one breeding season a year it was possible to compare the pattern and number of estradiol concentrating cells in the brains of estrous versus anestrous animals. Five female mink (three estrous; two anestrous) were ovariectomized, and one week later administered 3H-estradiol. The animals were sacrificed, and autoradiograms were prepared with the method for steroid autoradiography used routinely in this laboratory (Pfaff and Keiner, '73). The entire brain was sampled and subsequently analyzed with the aid of a light microscope.The majority of estradiol concentrating cells were found in the hypothalamus and limbic system, although a small number were seen in other structures. Specifically, structures containing a large number of estradiol concentrating cells were: the ventral lateral septum, the bed nucleus of the stria terminalis, the medial preoptic area, medial anterior hypothalamus, the ventromedial and arcuate nuclei of the hypothalamus, the medial and cortical nuclei of the amygdala, and the anterior pituitary. Structures containing a small number of estradiol concentrating cells were also seen in the telencephalon and diencephalon. The most posterior population of estradiol concentrating cells was in the central grey of the mesencephalon. No difference in the neuroanatomical pattern or number of estradiol concentrating cells was seen when the autoradiograms from estrous animals were compared to those from anestrous animals.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091890406
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