ISSN:
1572-994X
Keywords:
measles virus
;
measles vaccine
;
attenuated strain
;
molecular cloning
;
genome sequence
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Twelve cDNA clones covering the entire genome of the AIK-C strain of a seed for live measles vaccine were obtained, and the nucleotide sequences were determined. The full viral genomic RNA consists of 15,894 nucleotides. Comparisons of the nucleotide sequence and the deduced amino acid sequence between the AIK-C and other Edmonston strains revealed the following changes: 56 nucleotide differences and one C residue insertion, 31 amino acid changes, and 19 silent mutations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01702349
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