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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 65 (1989), S. 1936-1941 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report studies of the molecular-beam-epitaxial growth of In2Te3. The unique structure of In2Te3, with 1/3 of the In sublattice sites vacant, is of fundamental interest for molecular-beam-epitaxial growth dynamics. We show that thin-film (500–7000 A(ring)) single-crystal In2Te3 can be grown successfully on InSb(100) homoepitaxial layers at substrate temperatures of 300–350 °C and Te/In flux ratios of 3/2 to 5/2. Epitaxy has been monitored by reflection high-energy electron diffraction and the stoichiometry of the grown layers assessed by Auger spectroscopy and energy dispersive x-ray analysis. Raman studies of the layers are presented and compared with a bulk In2Te3 standard. Crystal structure has been determined by x-ray diffraction using Weissenburg and oscillation photographs, confirming that the layers have a fcc crystal structure with a lattice parameter of 18.50 A(ring), in excellent agreement with the bulk value. Band-gap measurements have been performed on the layers by photoreflectance. We report a value for the α-In2Te3 band gap of 1.19 and 1.31 eV at 300 and 77 K, respectively. Molecular-beam-epitaxial growth of InSb and CdTe on epitaxial In2Te3 films for fabrication of InSb/In2Te3/InSb and InSb/In2Te3/CdTe multilayers has been studied. Auger depth profiling of the resulting layers shows severe intermixing into the In2Te3. These results are supported by thermodynamic considerations of the InSb-In2Te3 interface.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 1873-1877 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have used the technique of molecular-beam epitaxy to grow layers of CdTe on InSb and InSb on CdTe and have performed a detailed analysis of the layers and their interfaces using Auger depth profiling and reflection high-energy electron diffraction. We show that significant improvements in interfacial quality can be obtained by the proper choice of fluxes during growth. The use of a Cd/Te flux ratio of 3:1 (JCd/JTe=3) during the growth of CdTe has enabled epitaxy at a substrate temperature of 300 °C. Interfaces formed with this flux ratio are abrupt, in sharp contrast to those formed under stoichiometric flux conditions (JCd/JTe=1). Subsequent growth of InSb at a substrate temperature of 300 °C on thin CdTe epilayers (400 and 800 A(ring)) is examined as a function of the InSb growth rate and Sb/In flux ratio. Quality of the interfaces shows a progressive improvement with increasing InSb growth rate.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Journal of cutaneous pathology 29 (2002), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Criteria for distinguishing between cutaneous lymphoid hyperplasia (CLH) and low-grade B-cell lymphoma are not well defined. We examined the hypothesis that the presence of a clonal B-cell population in heavy multinodular lymphoid infiltrates correlates with clinical presentation and outcome.Methods:  We identified 29 patients with skin lesions characterized histologically by a heavy dermal lymphocytic infiltrate with a multinodular architecture and extension into deep dermis and subcutaneous fat. Clonality was assessed immunophenotypically by light-chain restriction and also by analysis for IgH-gene rearrangement using PCR on DNA extracted from paraffin blocks.Results:  Follow-up (mean 80 months; median 45 months) was obtained in all patients. Twenty-four patients (83%) presented with a solitary lesion: only four had solitary recurrences, and none developed multiple synchronous lesions or systemic B-cell lymphoma. However, 9/24 of these solitary lesions (38%) were clonal by light-chain restriction or IgH PCR; 5/29 patients (17%) presented with multiple recurrent lesions and continued to develop lesions during the period of follow-up; 3/5 patients (60%) with multiple lesions demonstrated a B-cell clone. No patient developed systemic B-cell lymphoma.Conclusions:  Heavy, multinodular cutaneous lymphoid infiltrates have an excellent prognosis. Multiple lesions at presentation are the best predictor of recurrent multiple lesions confined to the skin. The presence of a clonal B-cell population does not correlate with clinical presentation or histology, nor does it predict development of further lesions or systemic lymphoma.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Journal of cutaneous pathology 32 (2005), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The histology of melanocytic nevi in elderly patients often differs from nevi in younger adults. Our hypothesis was that nevi in patients3 60 yrs would demonstrate histologic patterns different from nevi in younger adults. Biopsies of nevi (n = 214) from 172 patients3 60 yrs (mean age 69 ± 7 yrs) were examined by three dermatopathologists and a consensus diagnosis was rendered. Control specimens (n = 82) from 58 patients 20–40 yrs (mean age 31 ± 5 yrs) were evaluated. Compound melanocytic nevi were commoner in younger patients (37%) versus older patients (12%)(p 〈 .0001). Junctional melanocytic nevi were more frequently diagnosed in older patients (10% versus 3%; p = .027) and a lentiginous, often heavily pigmented, growth pattern was common (12% of nevi) vs control group (3%; p = .028). Atypical (“dysplastic”) nevi had a similar frequency at all ages, however 12/214 nevi in elderly patients (6%) exhibited marked atypia with features suggesting melanoma in-situ. We conclude that benign junctional nevi are relatively common in elderly patients and that a lentiginous, heavily pigmented growth pattern, typically associated with younger patients, is often seen in both junctional and compound nevi in this older age group. This pattern must be differentiated from dysplastic nevus and melanoma in-situ, which they may clinically resemble.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Background A major challenge in the histopathological examination of scalp biopsies is to perform an adequate evaluation of all the hair follicles present in the tissue. Transverse sectioning is currently the preferred technique to demonstrate every follicular structure in a punch biopsy specimen, although diagnostic accuracy is dependent on subjective evaluation of follicular morphology and hair size. Objectives To determine if computer-based morphometry and three-dimensional (3D) image reconstruction software can be used to evaluate scalp biopsies from patients with non-cicatricial alopecias. Methods Nine 4-mm scalp punches were taken from nine patients with noncicatricial alopecias and step-sectioned transversely at 0·1-mm intervals from the epidermal surface to the subcutaneous fat. Each tissue section was then digitized and analysed using morphometric and 3D image reconstruction software. Morphometric data and 3D images were collated with clinical and conventional light microscopic diagnoses, as well as follow-up information. Results In four of the nine patients, results of morphometric analysis concurred with conventional clinicopathological diagnoses. In the remaining five patients, morphometry revealed a lower telogen count in one patient and higher telogen count in four patients. One of the four patients with a higher telogen count also had a low mean hair diameter and miniaturized anagen follicles in the 3D image that were suggestive of early androgenetic alopecia (AGA). 3D virtual microscopic imagery allowed the direct visualization of colour-coded, scaled hair follicles which demonstrated characteristic changes in alopecia areata, AGA and telogen effluvium. Conclusions Our study demonstrated the feasibility of using morphometric and 3D reconstruction software to evaluate scalp biopsies. With further validation, this technique may prove to be more sensitive to detect subtle quantitative and qualitative follicular changes in non-cicatricial alopecias.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Surface Science 109 (1981), S. L539-L544 
    ISSN: 0039-6028
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Surface Science 64 (1977), S. 23-42 
    ISSN: 0039-6028
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Surface Science Letters 109 (1981), S. L539-L544 
    ISSN: 0167-2584
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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