Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Anaesthesia
49 (1994), S. 0
ISSN:
1365-2044
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The influence of timing of administration of peroperative alfentanil on pain and analgesic requirements after surgery was studied in 60 patients undergoing total abdominal hysterectomy with or without bilateral salpingo-oophorectomy. Thirty patients received alfentanil 7.5μg.kg-1 on induction of anaesthesia, followed by alfentanil 7.5μg.kg-1 90s before surgical incision (group A). Thirty control patients received alfentanil 15μg.kg-1, 10 min after abdominal incision (group B). In addition, 10min after surgical incision both groups received morphine 0.2mg.kg-1, given over a 10min period. The visual analogue scores (median, interquartile range) for pain 24 h after operation were 28.5 mm (11.25–47.0) in group A and 21.0 mm (10.5–47.5)in group B, p = 0.76. There were no differences in visual analogue scores at intermediate times. Morphine consumption in the first 24 h after surgery (median, interquartile range) was 53.5mg (37.25–60.0) in group A and 52.0mg (39.75–71.0) in group B, p = 0.52. We conclude that postoperative morphine consumption and pain scores are no different when alfentanil 15μg.kg-1 is given before or after skin incision for abdominal hysterectomy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2044.1994.tb04363.x
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