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  • 1
    Electronic Resource
    Electronic Resource
    Kinetic modeling of copolymerization/crosslinking reactions (1986)
    s.l. : American Chemical Society
    Macromolecules 19 (1986), S. 2174-2182 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00162a012
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  • 2
    Electronic Resource
    Electronic Resource
    Polymer chain entanglements and brittle fracture (1988)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 88 (1988), S. 1337-1342 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A stochastic model is presented to predict the molecular weight dependence of the polymer fracture energy and strength for polymers with molecular weights higher than the critical value corresponding to the onset of entanglements. A chain scission criterion is invoked for the polymer chain segments crossing the fracture plane and being entangled about it. The presence of dangling ends is shown to be responsible for the change of the fracture properties with molecular weight. The predictions of the model agree with experimental data of the fracture energy and strength of poly(methyl methacrylate) and polystyrene.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.454205
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  • 3
    Electronic Resource
    Electronic Resource
    PHOTOINITIATED POLYMERIZATION OF BIOMATERIALS (2001)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 31 (2001), S. 171-181 
    Details
    ISSN: 1531-7331
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Photoinitiated polymerization and polymer crosslinking are viable strategies for biomaterial synthesis because of the mild temperatures and neutral pH environments in which these reactions typically take place. This review summarizes the relevant theories as well as current status of photoinitiated polymerizations in biomaterials. Photoinitiation, photoinitiated polymerization, and photoinitiators are discussed with consideration toward the biological nature of the intended application. Recent investigations into biomaterials, including hydrogels, biodegradable materials, and hard tissue resorbable scaffolds are presented. Lastly, studies of cell interactions with photoinitiated biomaterials are discussed. The work herein illustrates the potential use of photoinitiated polymerization in the development of novel biomaterials for tissue engineering.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.matsci.31.1.171
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  • 4
    Electronic Resource
    Electronic Resource
    Bone tissue engineering (1995)
    [s.l.] : Nature Publishing Group
    Nature medicine 1 (1995), S. 1322-1324 
    Details
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Skeletal deficiencies resulting from trauma, tumours or abnormal development frequently require surgical intervention to restore normal tissue function. Even though current surgical treatments are often successful, all have associated problems and limitations. The limited supply of autograft tissue ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nm1295-1322
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  • 5
    Electronic Resource
    Electronic Resource
    Polymer chain entanglements and brittle fracture. III. Critical fracture strength of macromolecular materials (1989)
    Springer
    Journal of materials science 8 (1989), S. 833-834 
    Details
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01730153
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  • 6
    Electronic Resource
    Electronic Resource
    Growth Factor Delivery for Tissue Engineering (2000)
    Springer
    Pharmaceutical research 17 (2000), S. 497-504 
    Details
    ISSN: 1573-904X
    Keywords: tissue engineering ; growth factors ; controlled release ; bone ; nerve ; liver
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A tissue-engineered implant is a biologic-biomaterial combination in which some component of tissuehas been combined with a biomaterial to create a device for the restoration or modification of tissue ororgan function. Specific growth factors, released from a delivery device or from co-transplanted cells,would aid in the induction of host paraenchymal cell infiltration and improve engraftment of co-deliveredcells for more efficient tissue regeneration or ameliorate disease states. The characteristic properties ofgrowth factors are described to provide a biological basis for their use in tissue engineered devices. Theprinciples of polymeric device development for therapeutic growth factor delivery in the context of tissueengineering are outlined. A review of experimental evidence illustrates examples of growth factor deliveryfrom devices such as micropaticles, scaffolds, and encapsulated cells, for their use in the applicationareas of musculoskeletal tissue, neural tissue, and hepatic tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007502828372
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  • 7
    Electronic Resource
    Electronic Resource
    Brittle fracture of low molecular weight polymers (1989)
    Springer
    Journal of materials science 24 (1989), S. 1612-1616 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A new model is presented to predict the fracture energy of polymers with molecular weights smaller than the threshold value for the formation of chain entanglements. A fracture mechanism is assumed that calls for the sliding of the polymer chains in a microscopic craze at the crack tip. The plastic work is related to the chain interpenetration distance, which has been derived from the solution of the Fokker-Planck equation. The predictions of the model agree with experimental data of the fracture energy of polystyrene.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01105680
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  • 8
    Electronic Resource
    Electronic Resource
    The physical mechanism for the production of hydrophilic polymer microparticles from aqueous suspensions (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 40 (1990), S. 997-1004 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A previously reported method of producing spherical, hydrophilic microparticles by aqueous suspension polymerization is experimentally investigated. The phase separation is the result of a salting-out phenomenon. Characteristics of the salting-out effect between the monomer and suspending phase of aqueous NaCl solution are studied. The size and shape of the produced particles are characterized. It is concluded that the mechanism of polymerization is actually a combination of suspension and solution polymerization, and that the water content in the monomer phase is low enough to produce structurally homogeneous particles.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1990.070400532
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  • 9
    Electronic Resource
    Electronic Resource
    Review: Hydrogels for cell immobilization (1996)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 50 (1996), S. 357-364 
    Details
    ISSN: 0006-3592
    Keywords: hydrogel ; cell immobilization ; surface adhesion ; matrix entrapment ; microencapsulation ; immunoisolation ; bioartificial organs ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Hydrogels are being investigated for mammalian cell immobilization. Their material properties can be engineered for biocompatibility, selective permeability, mechanical and chemical stability, and other requirements as specified by the application including uniform cell distribution and a given membrane thickness or mechanical strength. These aqueous gels are attractive for analytical and tissue engineering applications and can be used with immobilization in therapies for various diseases as well as to generate bioartificial organs. Recent advances have broadened the use of hydrogel cell immobilization in biomedical fields. To provide an overview of available technology, this review surveys the current developments in immobilization of mammalian cells in hydrogels. Discussions cover hydrogel requirements for use in adhesion, matrix entrapment, and microencapsulation, the respective processing methods, as well as current applications. © 1996 John Wiley & Sons, Inc.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 10
    Electronic Resource
    Electronic Resource
    Reaction engineering aspects of suspension polymerization (1986)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 31 (1986), S. 2647-2659 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Suspension polymerization is used for the production of polymer particles with diameter in the range of 50-750 μm. The particle size distribution of the particles produced in batch-suspension polymerization is calculated using a population balance model. Power laws are derived for the average particle size and the standard deviation of the distribution. It is found that both quantities scale to the stable droplet mass of the initial dispersion of the organic phase into the aqueous one, which is a function of the agitation rate and the surface tension.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1986.070310820
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