ISSN:
1573-8353
Keywords:
cis-β-amino alcohols
;
4-hydroxyazolidin-2-ones
;
di[1,3]oxazolo[3,4-d:4,3-g]diazepine-3,8-diones
;
[1,3]dioxolo[4',5':6,7]naphtho[1,2-d][1,3]oxazol-2(1H)-ones
;
[1,3]oxazolo[4,3-a]isoquinolin-3-ones
;
calycotomine
;
intramolecular amidoalkylation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The reaction of intramolecular amidoalkylation of 4-hydroxyoxazolidin-2-ones leads to formation of novel and rare heterocyclic systems: substituted 1,5,6,10b-tetrahydro[1,3]oxazolo[4,3-a]isoquinolin-3-ones, 3a,4,5,10b-tetrahydro[1,3]dioxolo[4',5':6,7]naphtho[1,2-d][1,3]oxazol-2(1H)-ones, and 5,6,10,10a-tetrahydro-1H-di[1,3]oxazolo[3,4-d:4,3-g][1,4]diazepine-3,8-diones. Mild reaction conditions and the simplicity of isolation of the compounds formed make it possible to obtain the indicated heterocycles in high yields.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1002881002737
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