Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Event-related brain potentials and the perception of a phonetic continuum
    Amsterdam : Elsevier
    Biological Psychology 24 (1987), S. 197-207 
    Details
    ISSN: 0301-0511
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Psychology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0301-0511(87)90002-0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Ethanol-induced disturbance in human arousal mechanism (1981)
    Springer
    Psychopharmacology 73 (1981), S. 223-229 
    Details
    ISSN: 1432-2072
    Keywords: Ethanol ; Human EEG ; Arousal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of intravenous ethanol on EEG were analyzed in 11 healthy subjects. During the rapid infusion phase the breath alcohol concentration (BRAC) was raised in 1 h to about 1 mg/ml and kept at this level for 90 min by adjusting the infusion rate. Thereafter the infusion was stopped and EEG was monitored for a further hour with falling alcohol concentration. At the end of the rapid infusion phase venous blood alcohol concentrations (BACs) were comparable to BRACs but during the slow infusion and the post-infusion phase BACs were always higher than the corresponding BRACs. Significant changes in EEG occurred during the test. The amplitude increased, the mean frequency decreased (after a slight initial increase in some subjects) and the desynchronization of EEG due to eye opening weakened. The changes in EEG during the slow infusion phase and after infusion paralleled the BACs whereas the BRAC values in the phases were unreliable for predicting EEG changes. In general the EEG changes were smaller when the blood and breath alcohol concentrations were rising than at the corresponding concentrations when the alcohol concentration was falling. Qualitatively the changes in EEG reactions were similar in all subjects, but quantitatively there were statistically significant interindividual differences. Subjective alertness showed a significant negative correlation with activity and a positive correlation with mobility during the test session. A significant decrease in alertness corresponded to a decrease in the desynchronization of EEG by eye opening in the slow and post-infusion phases of the test session. The results indicate that the neurophysiological effects of ethanol consist of immediate, direct effects, and late, indirect, effects which are probably mediated by metabolicneuroendocrine mechanisms in brain structures controlling EEG arousal and subjective feelings of alertness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422407
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Quantitative effects of ethanol infusion on smooth pursuit eye movements in man (1982)
    Springer
    Psychopharmacology 77 (1982), S. 74-80 
    Details
    ISSN: 1432-2072
    Keywords: Ethanol ; Smooth pursuit ; Eye movements
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of intravenously administered ethanol on visuomotor performance were analyzed in 11 healthy subjects. During the rapid infusion phase the breath alcohol concentration (BRAC) rose to about 0.1% in 1 h and was kept at this level for 90 min by adjusting the infusion rate. Thereafter the infusion was stopped and eye movements were recorded for a further hour with falling alcohol concentration. Significant changes in smooth pursuit eye movements occurred during the test. The total amount of horizontal correction in pursuit of a spot moving in a circular pattern increased significantly. The increase was clearly greater when the eyes moved below the horizontal level from right to left. No significant differences were detected between the right and the left eyes. At the start of the rapid infusion the number of corrections increased until their maximum value/cycle. Thereafter the increase in the total amount of correction was due to the increase in the amplitude of single corrections. The correction curves closely followed venous blood alcohol concentration curves but were clearly different from breath alcohol concentration curves in the steady-state and in the postinfusion phase. These changes are probably due to the increasing phase lag between the eyes and the target. This in turn may depend on impaired arousal mechanism. Interindividual differences in smooth pursuit eye movements were large even in the control situation. Subjects with saccadic over- or undershoots or phase difference between the eyes tended to have more disturbed smooth pursuit eye movements, both in the control and test situations. In one “normal” subject corrective saccades were replaced by “glissadic” movements at a blood alcohol concentration level of about 0.1%. Therefore it is suggested that subjects with latent eye movement disorders are especially sensitive to the effects of ethanol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00436102
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Difference in action between oral triazolam and zopiclone (1990)
    Springer
    European journal of clinical pharmacology 38 (1990), S. 47-51 
    Details
    ISSN: 1432-1041
    Keywords: Triazolam ; zopiclone ; pharmacodynamics ; quantitative EEG ; saccadic eye movements ; psychometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of oral triazolam 0.25 mg and zopiclone 7.5 mg in 7 supine volunteers were compared by means of quantitative measurements of the EEG, saccadic eye movements, visual analogue scale (VAS) for alertness, critical flicker fusion frequency (CFF) and the Maddox wing. Zopiclone reached its maximum effect earlier (62 min) than triazolam (91 min; CFF). On linear regression analysis the average rate constant (regression coefficient) of onset of action of zopiclone was significantly greater than that of triazolam (0.29 vs. 0.17). Triazolam and zopiclone had similar effects, but zopiclone seemed to have a faster onset of action, probably indicating swifter absorption in supine subjects. Quantitative EEG evaluation gave parallel results to the other parameters used, but triazolam and zopiclone showed a dissimilar mechanism of action, as characterized by changes in the alpha frequency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314802
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...