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  • 1
    ISSN: 1432-184X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Cyanobacterial blooms were sampled at five locations in Lake Grand-Lieu on seven different occasions during May–October 1994. Strains of Microcystis aeruginosa and Anabaena circinalis were isolated from the samples. Microcystins were detected in freeze-dried field samples and the isolated strains by HPLC. The toxins were present in the blooms sampled between June and October. The microcystin content in the blooms varied with site and time, from undetectable concentrations to 0.23 mg g−1. The highest concentrations of microcystin were found in blooms sampled in September. Microcystin-LR and microcystins with retention times close to the retention time of [Dha7]microcystin-RR (probably varieties of microcystin-RR) were found in the field samples. Sixteen of the 98 isolated M. aeruginosa strains and 2 of the 24 A. circinalis strains produced microcystins. The total amount of microcystins varied from undetectable concentrations to 5.06 mg g−1 in the M. aeruginosa isolates, and from undetectable concentrations to 1.86 mg g−1 in the A. circinalis strains. Microcystin-LR was the main toxin found in strains of M. aeruginosa, but was not present in strains of A. circinalis. Both microcystin-producing strains and strains that did not produce microcystin coexisted in the bloom samples.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 38 (1990), S. 47-51 
    ISSN: 1432-1041
    Keywords: Triazolam ; zopiclone ; pharmacodynamics ; quantitative EEG ; saccadic eye movements ; psychometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of oral triazolam 0.25 mg and zopiclone 7.5 mg in 7 supine volunteers were compared by means of quantitative measurements of the EEG, saccadic eye movements, visual analogue scale (VAS) for alertness, critical flicker fusion frequency (CFF) and the Maddox wing. Zopiclone reached its maximum effect earlier (62 min) than triazolam (91 min; CFF). On linear regression analysis the average rate constant (regression coefficient) of onset of action of zopiclone was significantly greater than that of triazolam (0.29 vs. 0.17). Triazolam and zopiclone had similar effects, but zopiclone seemed to have a faster onset of action, probably indicating swifter absorption in supine subjects. Quantitative EEG evaluation gave parallel results to the other parameters used, but triazolam and zopiclone showed a dissimilar mechanism of action, as characterized by changes in the alpha frequency.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 31 (1987), S. 673-676 
    ISSN: 1432-1041
    Keywords: buprenorphine ; fentanyl ; critical flicker fusion threshold-test ; Maddox wing readings ; visual analoque scale scores ; healthy volunteers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary We have tested the usefulness of the critical flicker fusion threshold-test (CFF), Maddox wing readings (MW), and visual analoque scale scores (VAS) in a double-blind, random-order study designed to evaluate the clinical effects of two different kinds of opiates, buprenorphine and fentanyl in comparison with those of placebo. The results were compared with the so-called postanaesthetic recovery score (PARS). In 7 healthy volunteers MW and VAS differentiated the effects of buprenorphine 7.5 µg/kg i.v. from those of fentanyl 2.5 µg/kg i.v. and placebo. CFF was very insensitive in this respect and PARS completely useless. Our results show that, in addition to the known usefulness of VAS, MW is also able to differentiate the effects of these opiates.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Dental traumatology 9 (1993), S. 0 
    ISSN: 1600-0595
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract The guarding capacity of seven mouth protectors (Erkoflex 3.0 and 4.0, Erkoloc 3.0, 4.5 and 5.5, TranSheet/Perform and TranSheet/LiteLine) was tested mechanically on 20 plaster models, two or three tests on each mouth protector. Two tests on a plaster model without the protector screed as control. An appliance was constructed to simulate the impact of an ice-hockey puck on the teeth, the plaster model was fixed onto the device and the minimum force needed to break the plaster teeth under the protector was recorded. The average total thickness and that of the soft and hard layers of the labial plates of each mouth protector were recorded along with the average thickness of the cervical and incisal hard and soft layers. The results showed that the best protection was achieved with the TranSheet/LiteLine model, followed by TranSheet/Perform and Erkoloc 5.5 and 4.5 mouthgards. All these had a resilient layer against the teeth, and it was shown in stepwise regression analysis that the only property having a statistically significant effect on the guarding capacity was the thickness of this cervical soft layer.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 24 (1997), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Periotest values (PTV) of successful endosseal implants of 2 one-stage implant systems, TPS and ITI, were followed from 3 months to 9 years in order to determine the factors that contribute to the values. 128 TPS screw implants were inserted in the lower jaw of 34 subjects, (mean age 55 years), for retaining overdentures. 108 ITI implants were inserted in the upper and lower jaws in 50 subjects (mean age 42 years), for retaining overdentures, crowns and bridges. PTVs were first measured after the osseointegration period and thereafter annually. First of all, there was a difference between the 2 implant systems. Mean PTVs of TPS bicortical screws were significantly lower (p〈0.05) than those of ITI implants (screws, hollow-screws, hollow-cylinders). Factors which significantly contributed to PTVs of ITI implants were jaw (upper/lower), implant length and region of the jaw in which the implant was inserted. PTVs of ITI implants in the lower jaw were lower than in the upper jaw (p〈0.05). The length of implant had no effect on PTVs in the lower jaw, but in the upper jaw, PTVs of ITI 8–10-mm implants were lower than 12-mm implants (p〈0.05). PTVs of implants inserted in the anterior region of the upper jaw were higher than those in the posterior region (p〈0.05). In conclusion, bone quality and implant length had a statistically significant effect on implant mobility in long-term follow-up. PTVs of various implant systems, however, differ, a fact that must be taken into account in evaluating the success of implants.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 44 (1989), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An infusion of propofol was compared with intravenous boluses of diazepam as sedation for minor oral surgery under local anaesthesia in 12 healthy patients who had elective bilateral surgical extraction of lower third molars; the patients served as their own controls. Plasma catecholamine, vasopressin and cortisol concentrations were determined from repeated blood samples. The total administered dose of propofol was 3.93 (SD 1.34) mg/kg and of diazepam 0.28 (SD 0.07) mg/kg. No cardiovascular depression or airway problems occurred. Other side effects were also rare but some discomfort on injection was frequent with propofol. Recovery times were faster after propofol than after diazepam as assessed by the Maddox wing and visual analogue scales. Propofol also provided better amnesia compared to diazepam at the time of the extraction of the teeth. Eight of the 12 patients subjectively preferred propofol sedation. There was no hormonal stress response in either group.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 44 (1989), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of oral temazepam (20 mg), oral midazolam (15 mg) and a placebo were compared for night sedation on the evening prior to surgery in a double-blind study. Patients in the placebo group had significantly worse sleep than those in the temazepam (p = 0.004) or midazolam groups (p = 0.04). There was no significant difference between the two drug groups, nor between the residual effects of the three treatments. Temazepam appears to be somewhat more effective than the ultrashort-acting midazolam in pre-operative transient insomnia.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Due to extensive loss of tooth substance the restoration of endodontically treated tooth requires intracanal dowels to give an efficient strength for the crown. The aim of our study was to investigate whether the previous type of restoration of the tooth, i.e. composite restoration with screw post versus one-piece dowel crown, has an effect on the prognosis of crowns with dowels. The material consisted of 111 single crowns and as a previous restoration there were 83 composite restorations with screw posts and 28 one-piece dowel crowns. The mean follow-up time was 78 months (range 6–163 months). The cumulative survival was 87% for one-piece dowel crowns and 84% for composite resins with screw posts. There were six root fractures, four losses of cement retention and one tooth extraction due to caries in crowns with previous composite resin with screw posts. In one-piece dowel crowns as a previous restoration there were two root fractures and one tooth extraction for periodontal reasons. In conclusion, it seems that the previous restoration has no marked effect on the prognosis of crowns with dowels when studying a composite resin restoration with screw post and a one-piece dowel crown.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd
    Journal of oral rehabilitation 28 (2001), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Even if implant therapy is very common nowadays, treatment with conventional fixed bridge prosthesis still has indications and cannot be forgotten. Because of improved dental health more teeth can be preserved and more fixed prostheses are prepared also for the elderly. The aim of this study was to discuss the future of treatment need in fixed metal ceramic bridge prostheses based on the analysis of distribution of pontics in dentition in four different age groups during the years 1984–1996. Data were collected from the patient files. The numbers of upper lateral incisors, upper first premolars and lower first molars were analysed in years 1984–1987, 1988–1992 and 1993–1996 between and within age groups of under 34, 35–49, 50–64 years and over 65 years. As a conclusion, in the future the treatment need for fixed bridge prostheses will be highest among patients over 50 years and their most replaced teeth are, besides lower first molars, the upper first premolars.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 24 (1997), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary The effect of complete denture renewal on oral health was evaluated both subjectively and clinically at follow-up 30 months (range 19–36 months) after completion of treatment in 42 edentulous patients (31 women and 11 men, aged 34–76 years) treated by dental students during 1989–1992. Ninety per cent of the patients were satisfied with the new appearance of their dentures and 71% with the way they functioned. When comparing the base data and results from follow-up it seems that general health and medication, anatomical circumstances, salivary flow rates and denture wearing habits in edentulous subjects do not change significantly over a few years. The main effects of denture renewal are seen in patient satisfaction, and clinically in the improved condition of oral mucosa and better fit and acceptable occlusion of dentures.
    Type of Medium: Electronic Resource
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