ISSN:
1432-1041
Keywords:
buprenorphine
;
fentanyl
;
critical flicker fusion threshold-test
;
Maddox wing readings
;
visual analoque scale scores
;
healthy volunteers
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary We have tested the usefulness of the critical flicker fusion threshold-test (CFF), Maddox wing readings (MW), and visual analoque scale scores (VAS) in a double-blind, random-order study designed to evaluate the clinical effects of two different kinds of opiates, buprenorphine and fentanyl in comparison with those of placebo. The results were compared with the so-called postanaesthetic recovery score (PARS). In 7 healthy volunteers MW and VAS differentiated the effects of buprenorphine 7.5 µg/kg i.v. from those of fentanyl 2.5 µg/kg i.v. and placebo. CFF was very insensitive in this respect and PARS completely useless. Our results show that, in addition to the known usefulness of VAS, MW is also able to differentiate the effects of these opiates.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00541294
