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  • 1
    ISSN: 0003-2697
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 154 (1988), S. 489-496 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 142 (1987), S. 559-566 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 148 (1987), S. 1390-1397 
    ISSN: 0006-291X
    Keywords: [abr] 100,000 Da ; [abr] phenylmethylsulfonyl fluoride; PMSF ; [abr] phosphoprotein; pp100 ; [abr] sodiumdodecyl sulfate-polyacrylamide gel electrophoresis; SDS-PAGE
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 148 (1987), S. 1390-1397 
    ISSN: 0006-291X
    Keywords: [abr] 100,000 Da ; [abr] phenylmethylsulfonyl fluoride; PMSF ; [abr] phosphoprotein; pp100 ; [abr] sodiumdodecyl sulfate-polyacrylamide gel electrophoresis; SDS-PAGE
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 6
    ISSN: 1432-2218
    Keywords: Laparoscopic bile duct injury ; Routine intraoperative cholangiography ; Biliary tract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Controversy over whether intraoperative cholangiography (IOC) should be done routinely has intensified since the advent of laparoscopic cholecystectomy (LC). As yet, no study has demonstrated a clear benefit to its use, although their have been suggestions in the literature that routine use may confer an advantage to detection of injuries. One-hundred seventy-seven biliary tract complications occurring secondary to LC were identified from the combined data of seven institutions. The goal of this retrospective study was to examine the impact of IOC on the occurrence, recognition, and correction of such complications. The complications identified include 39 cystic duct leaks, 69 major ductal leaks or strictures, and 69 major ductal transection or excision injuries. Whether IOC was performed was known in 157 (88%) patients with 53 patients definitely having and 104 not having an IOC. Data concerning IOC were unavailable in 20 cases. More injuries were detected intraoperatively in the group having IOC (P〈0.001). Conversion of the LC to a laparotomy, often for repair of the injury, occurred more commonly in the group having a correctly interpreted IOC (P〈0.001). Conversion resulted in detection of injuries sooner, resulting in fewer operative procedures to correct the injury (P〈0.001). A transecting injury was prevented in at least seven patients when no visualization of the proximal biliary tree was documented by IOC. These partial ductal incisions were treated by t-tube placement. Incorrect interpretation of the IOC occurred in at least eight patients, with no identification of the proximal biliary tree in six. These data suggest routine IOC may offer significant potential advantages in the detection and subsequent correction of these injuries, as well as preventing extension of partial ductal incisions to complete ductal transections. Surgeons must be able to correctly interpret the IOC. Although routine IOC is suggested, careful dissection principles continue to be most important in the prevention of major extrahepatic bile duct injuries during LC.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 9 (1995), S. 164-168 
    ISSN: 1432-2218
    Keywords: Paraesophageal hernia ; Nissen fundoplication ; Sliding hiatal hernia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Large paraesophageal hernias are generally repaired by reduction of the stomach into the abdomen, sac excision, crural closure, and gastropexy or fundoplication. After gaining experience performing laparoscopic repair of sliding hiatal hernias and Nissen fundoplication we combined laparoscopic access with traditional surgical technique in treating patients with complex paraesophageal hernias. Ten adults, six males and four females, with type III paraesophageal hernias underwent laparoscopic repair between February 1993 and April 1994. The average age of the patients was 60.4 years (range 38–81). Using five ports (three 10 mm and two 5 mm), the stomach was reduced into the abdomen, the hernia sac was resected, and the defect was closed with pledgeted horizontal mattress sutures. In addition, nine patients had a Nissen fundoplication performed and one patient had a diaphragmatic gastropexy. The procedure was completed laparoscopically in all ten cases and the median operating time was 282 min (range 165–430). Two complications occurred, an intraoperative gastric laceration, and a postoperative mediastinal seroma. All patients were discharged on the 2nd or 3rd postoperative day. Eight of nine patients were asymptomatic at last follow-up (mean 8.9 months postop). One patient has mild dysphagia and heartburn from partial migration of the fundoplication into the chest. One patient died 3 months postoperatively of unrelated causes. Paraesophageal hernia can be reduced and repaired safely with laparoscopic access using standard surgical techniques.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 12 (1998), S. 1055-1060 
    ISSN: 1432-2218
    Keywords: Key words: Hiatal hernia — Paraesophageal hernia — Gastroesophageal junction — Esophageal stricture — Collis gastroplasty — Laparoscopic Nissen fundoplication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: The short esophagus increases the difficulty and limits the effectiveness of laparoscopic Nissen fundoplication. In our experience, ∼20–25% of esophagi judged by preoperative criteria to be foreshortened will, after dissection, be insufficiently long to allow 2 cm of esophagus to reside below the diaphragm without inferior distraction (i.e., tension free). Collis gastroplasty combined with Nissen fundoplication has become the standard approach for the creation of an intraabdominal neoesophagus and fundic wrap. Methods: After developing methods of performing totally laparoscopic stapled gastroplasty in the cadaver lab in 1994, we started applying the technique clinically in 1996. We performed 220 laparoscopic antireflux procedures between January 1996 and July 1997. Of these 220 patients, 26% were suspected to have esophageal foreshortening based on preoperative barium studies and/or endoscopy. Results: After hiatal dissection, nine patients, or 16% of those suspected to have esophageal foreshortening and 4% of the entire population, required the laparoscopic Collis-Nissen procedure. There was symptomatic improvement in all patients as assessed by patient-initiated symptom scores. Conclusions: The management of patients with esophageal foreshortening is a complex problem. We believe that our technique of laparoscopic Collis-Nissen provides an effective means of achieving intraabdominal placement of the fundic wrap while maintaining the benefits of a minimally invasive approach.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 9 (1995), S. 426-429 
    ISSN: 1432-2218
    Keywords: Laparoscopic Nissen ; Cost comparison ; Belsey Mark IV
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Laparoscopic Nissen fundoplication is a relatively new technique used to treat gastroesophageal reflux disease (GERD). The purpose of this study was to compare the cost to the patient and insurer of a laparoscopic Nissen fundoplication (LN) to an open Belsey Mark IV (B4), the previous standard operation for GERD at Emory University Hospital. A retrospective review of 20 consecutive patients undergoing LN or B4 for GERD was performed. Patients were well matched for age, severity of disease, and comorbid illness. The data were analyzed using an unpaired Student's t-test or Wilcoxon signed rank analysis. The results are as follows (mean±SD): We conclude that the charges for laparoscopic Nissen fundoplication are significantly less than the charges for Belsey Mark IV. The majority of the savings resulted from a shortened hospital stay.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 9 (1995), S. 501-504 
    ISSN: 1432-2218
    Keywords: Nitrous oxide ; Pneumoperitoneum ; Combustion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Nitrous oxide has been effectively banned from use in therapeutic laparoscopy because of fear of combustion. These fears rest on two case reports, a misunderstanding of the physical chemistry of nitrous oxide, and lack of information on the presence of flammable colonic gases in the pneumoperitoneum mixture. This study aims to identify the presence and quantify the amount of hydrogen and methane found in the peritoneal cavity during laparoscopic GI procedures, and then to compare the gas concentrations detected with known limits of combustion. Gas standards with known concentrations of hydrogen and methane were placed in polypropylene syringes and analyzed on a mass spectrometer after 1, 2, 3, and 4 h. This established the rate at which these gases would be leached through a polypropylene syringe—the amount of gas lost during transport from the patient to the laboratory. Twenty gas samples were drawn, randomly, 30 min to 2 h following the start of laparoscopic gastrointestinal procedures. The samples were analyzed for hydrogen and methane within 30 min of their aspiration from the abdominal cavity. An inconsequential amount of methane was lost from the polypropylene syringe in 4 h. After 1 h, one-half the hydrogen had leached from the polypropylene syringe. Hydrogen was detected in the pneumoperitoneum of four patients at a concentration ranging from 0.016 to 0.075%. No methane was detected in any sample. For combustion to occur in a nitrous oxide environment, hydrogen or methane must occupy 5.5% of the gas volume. The maximum amount of hydrogen we detected was less than 1/50 of the combustion threshold. After considering these data, and a large clinical experience of gynecologic laparoscopy using electrosurgery in a nitrous oxide pneumoperitoneum, we conclude that nitrous oxide can be safely used for creating a pneumoperitoneum during laparoscopic surgery.
    Type of Medium: Electronic Resource
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