Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Ki-67 and biological behaviour in meningeal haemangiopericytomas (1996)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Histopathology 29 (1996), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The biological behaviour of meningeal haemangiopericytomas was retrospectively studied using immunohistochemical staining with MIB1, a monoclonal antibody against the Ki-67 antigen, a nuclear protein related to cell proliferation. Paraffin-embedded material from 62 tumours from 40 patients were investigated. The proliferating compartment of the tumours was estimated by evaluating the MIB1 staining index, i.e. the percentage of MIB1 positive nuclei in at least 1000 counted tumour cells in representative areas. The staining index ranged from 1.24% to 39.01%. Statistical analysis revealed no significant correlation between the staining index and recurrence-free survival (χ2 = 0.3922, P = 0.5311). Long-term observation (〉100 months), however, revealed a tendency to longer survival in the group with a staining index less than 5%. According to our results, the MIB1 staining index does not contribute to the accuracy of predicting the clinical outcome of meningeal haemangiopericytomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2559.1996.d01-479.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Paraneoplastische limbische Enzephalitis (1997)
    Springer
    Der Pathologe 18 (1997), S. 406-410 
    Details
    ISSN: 1432-1963
    Keywords: Schlüsselwörter Paraneoplastische neurologische Syndrome ; Limbische Enzephalitis ; Anti-Hu-Syndrom ; Kleinzelliges Bronchialkarzinom ; Key words Paraneoplastic neurological syndromes ; Limbic encephalitis ; Anti-Hu-syndrome ; Small cell lung cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We report on a 69-year old male patient who presented with vague depressive symptoms and loss of weight accompanied by lack of appetite, ageusia and anosmia. The patient died of bronchial pneumonia, and neuropathological examination revealed a so-called limbic encephalitis. The paraneoplastic origin of this case was later confirmed by discovery of a clinically inapparent, indolently growing small cell lung cancer. This case illustrates the difficult clinical diagnosis of paraneoplastic limbic encephalitis and the need for a close cooperation of pathologists and neuropathologists in the clarification of such cases.
    Notes: Zusammenfassung Berichtet wird über den Fall eines 69jährigen Mannes mit einer unklaren depressiven Symptomatik und Gewichtsabnahme in Verbindung mit Appetitlosigkeit, Ageusie und Anosmie. Der Patient verstarb an einer Bronchopneumonie, und die neuropathologische Untersuchung ergab den Befund einer sog. limbischen Enzephalitis. Die paraneoplastische Genese des Krankheitsbildes wurde dann a posteriori durch den Nachweis eines klinisch unbekannten, lokal indolent wachsenden kleinzelligen Bronchialkarzinoms bestätigt. Der Fall illustriert die schwierige klinische Diagnose einer paraneoplastischen limbischen Enzephalitis und unterstreicht die Notwendigkeit einer engen Zusammenarbeit von Pathologen und Neuropathologen in der Aufklärung derartiger Fälle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002920050234
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Paragangliom der Cauda equina (1997)
    Springer
    Der Pathologe 18 (1997), S. 484-487 
    Details
    ISSN: 1432-1963
    Keywords: Schlüsselwörter Paragangliom ; Ependymom ; Filum terminale ; Cauda equina ; Differentialdiagnose ; Key words Paraganglioma ; Ependymoma ; Filum terminale ; Cauda equina ; Differential diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We report on a case of paraganglioma of the cauda equina in a 48-year-old man. These slow-growing, mostly benign and encapsulated intradural–extramedullar tumours are clinically characterized by lumbago, paraesthesia and motor deficits as well as occasi-onally by incontinence. Paragangliomas of the cauda equina show monomorphous (main) cells arranged in a typical cell cluster pattern, demonstrating a lobular architecture and a fine net of connective tissue formed by so-called sustentacular cells; some tumours show focal ganglionic differentiation. Because of their morphological similarity to the more common ependymomas, paragangliomas of the cauda equina are sometimes misdiagnosed so that their incidence is likely to be higher than previously estimated. Immunohistochemistry findings are positive for neuron-specific enolase, chromogranin and other neuronal markers as well as neuropeptides (main cells) and S-100 protein (sustentacular cells) while widely lacking reactivity for GFAP. Paragangliomas of the cauda equina represent a rare entity, of which only 80 cases have been described in the literature. Because they only occur sporadically, they are often not included in the differential diagnosis of mass lesions of the region of the cauda equina.
    Notes: Zusammenfassung Wir berichten über ein Paragangliom der Cauda equina bei einem 48jährigen Patienten. Klinisch imponieren diese langsam intradural-extramedullär wachsenden, meist benignen und von einer bindegewebigen Kapsel umgebenen Geschwülste durch Lumbalgien, Parästhesien und Paresen sowie gelegentlich durch Inkontinenz. Paragangliome der Cauda equina zeichnen sich histomorphologisch durch monomorphe Zellen (Hauptzellen) in typischer „Zellballen”-anordnung mit lobulärer Architektur und feinem Bindegewebsnetz aus Hüllzellen (Sustentakularzellen) aus, z.T. liegt eine ganglionäre Differenzierung vor. Wegen ihrer Ähnlichkeit zum häufigeren Ependymom werden sie mitunter fehldiagnostiziert, so daß ihre Inzidenz wahrscheinlich höher ist als bislang angenommen. Immunhistochemisch exprimieren sie neuronspezifische Enolase, Chromogranin und andere neuronale Marker sowie Neuropeptide (Hauptzellen) und S-100-Protein (Sustentakularzellen) bei weitgehend fehlender Reaktion für GFAP. Das Paragangliom der Cauda equina ist eine seltene Entität, von der bislang erst 80 Fälle in der Literatur beschrieben worden sind und an der gerade aufgrund ihres sporadischen Auftretens bei der Differentialdiagnose von Raumforderungen in diesem Bereich oft nicht gedacht wird.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002920050247
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Congenital immature teratoma of the fetal brain (1997)
    Springer
    Child's nervous system 13 (1997), S. 556-559 
    Details
    ISSN: 1433-0350
    Keywords: Key words Fetus ; Brain tumor ; Congenital ; Teratoma ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Congenital intracranial tumors are very rare and only account for 0.5–1.5% of all childhood brain tumors. Even rarer are those with prenatal manifestation. The most common of these present at birth are teratomas, which show divergent differentiation with 90% of them containing tissues from all three germ layers. We report a rare case of an intrauterine congenital immature teratoma in a female fetus at 23 weeks of gestation, which was sonographically diagnosed in vivo by detection of the tumor and associated craniomegaly. Because of the poor prognosis, termination of the pregnancy was induced by Rivanol instillation. The cerebral tumor was confirmed at autopsy and was not associated with any other malformations. Histological and immunohistochemical features of this tumor are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003810050137
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...