ISSN:
1572-9931
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Multidrug resistance in several human cell lines correlates with amplification or increased expression of two related DNA sequences, designated mdr1and mdr2.These DNA sequences were used as probes for hybridization with DNA with a panel of human-mouse somatic cell hybrids and from individual human chromosomes separated by fluorescence-activated chromosome sorting. By these assays, both mdr1and mdr2sequences were localized to chromosome 7.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01570737
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