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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 41 (1986), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Antibodies to Aspergillus umbrosus were investigated in 181 Danish farmers, 137 farmers spouses and a control group of 104 male blood donors with no relation to farming. By enzyme-linked immunosorbent assay (ELISA) higher levels of IgG antibodies were found in farmers than in their spouses and in non-farming controls (P 〈 0.0001). By double immunodiffusion precipitating antibodies occurred in 11 farmers, in none of farmers' spouses and in one control subject. Farmers and farmers' spouses who were non-smokers had higher IgG antibody levels than smokers in the same groups (P 〈 0.04). Farmers more than 30 years of age had higher IgG antibody levels than younger farmers (P 〈 0.04). Farmers rearing cattle tended to have higher IgG antibody levels than farmers without cattle. No correlation between antibody levels and respiratory symptoms or lung function parameters (FEV1 or FVC) could be demonstrated.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 14 (1984), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Serum antibodies to avian and Aspergillus antigens were detected by enzyme-linked immunosorbent assays (ELISA) in forty-two workers from a poultry abattoir and in twenty healthy blood donors. The levels of IgG and IgA antibodies to hen and duck serum were significantly higher in poultry workers than in blood donors (P〈0.01). In workers employed for less than 1 year the antibody levels were lower than in those who had been employed for a longer period of time (P〈0.05). The IgA antibody level to a high molecular weight Aspergillus antigen was higher in poultry workers than blood donors (P〈0-05), whereas the level of other Aspergillus antibodies were similar in the two groups. The level of IgG antibodies to hen antigen was higher in non-smokers than in smokers (P〈0-02). A correlation between the antibody levels to hen and duck antigens and to pigeon antigen was found (P〈0.05). indicating cross-reactivity between these antibodies. No cases of allergic alveolitis were found, and no correlation between antibody levels and respiratory symptoms could be demonstrated.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 21 (2005), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Pyogenic liver abscess is a life-threatening disease. Accurate data on incidence and prognosis are important, but scarce.Aim : To examine changes in the incidence and 30-day mortality rate of patients with pyogenic liver abscess in Denmark.Methods : Using nationwide administrative registers, we identified all patients diagnosed with pyogenic liver abscess in Denmark, 1977–2002, and their dates of death. We computed annual standardized incidence and 30-day mortality rates, and used Poisson regression to adjust gender-specific mortality rates for year-by-year differences in age at diagnosis.Results : We identified 1448 patients with pyogenic liver abscess, of whom 54% were men. The crude incidence rate for the entire study period was 11.8 per 1 000 000 for men and 9.7 per 1 000 000 for women. Between 1977 and 2002, the incidence rate increased from 6 to 18 per 1 000 000 for men and from 8 to 12 per 1 000 000 for women. The cumulative 30-day mortality rate was 15% for men and 23% for women. The adjusted 30-day mortality rate decreased from 40% for men and 50% for women to around 10% for both genders.Conclusions : In this large nationwide study spanning a 26-year period, we found an increasing incidence rate and a decreasing mortality rate of pyogenic liver abscess. We believe that these changes are primarily explained by more sensitive diagnostic tools.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Small Ruminant Research 10 (1993), S. 357-362 
    ISSN: 0921-4488
    Keywords: Antibiotic therapy ; Immunohistochemistry ; Mycotic infection ; Zygomycosis
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mikrobiologische Befunde von Proben aus den tiefen Atemwegen von Kindern wurden im Hinblick auf den Anteil vonBranhamella catarrhalis und β-Laktamase-Produktion nachuntersucht. Im Jahre 1986 warB. catarrhalis aus 139 von 756 Proben (18,4%) und 1989 aus 211 von 723 Proben (29,2%) isoliertworden. 1986 waren 55,6% der Stämme vonB. catarrhalis β-Laktamasebildner; 1989 80,1% (p〈0,001). Die Prävalenz an β-Laktamasebildnern unterB. catarrhalis hat inzwischen in Europa dasselbe Ausmaß erreicht wie in den USA.
    Notes: Summary Findings in specimens from the lower respiratory tract of children were reviewed retrospectively in order to assess the rate ofBranhamella catarrhalis and β-lactamase production.B. catarrhalis was isolated in 139 of 756 samples (18.4%) in 1986 and 211 of 723 samples (29.2%) in 1989. Beta-lactamase production was found in 55.6% ofB. catarrhalis strains in 1986 and 80.1% in 1989 (p〈0.001). Prevalence of β-lactamase inB. catarrhalis has now reached the same level in Europe as in the USA.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Infection 21 (1993), S. 251-253 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Eine 59 Jahre alte Frau mit Nierenversagen wurde im Koma mit Krampfanfällen eingewiesen. Computertomographisch zeigte sich eine Läsion in der rechten Hemisphäre frontal; am Tag 12 waren neue Herde geringer Dichte in der rechten und linken Hemisphäre aufgetreten. Am Tag 13 wurde in der BlutkulturSalmonella typhimurium angezüchtet. Die Patientin verstarb am nächsten Tag. Autoptisch zeigte sich ein Hirninfarkt mit Abszedierung. Wegen der schwer faßbaren Erscheinungsformen der Infektionen durch nicht-Typus-Salmonellen erscheint es ratsam, bei empfänglichen Patienten mit Fieber oder ätiologisch ungeklärten Herd-Symptomen Blut- und Stuhlkulturen anzulegen.
    Notes: Summary A 59-year-old woman with renal failure was admitted in a coma with seizures. Computerized tomography (CT) revealed a frontal mass in the right cerebral hemisphere and on day 12 new low density areas had appeared in both the right and left hemisphere. Blood cultures on day 13 grewSalmonella typhimurium, and the patient died the next day. An autopsy showed cerebral infarction with abscess formation. The elusive features of non-typhoidSalmonella infections make it advisable to obtain blood and faecal cultures from susceptible patients with fever or focal disorders of unknown aetiology.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 10 (1991), S. 530-531 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 17 (1998), S. 690-694 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The incidence and case fatality rates of meningococcal disease were assessed in the county of Northern Jutland, Denmark, during the 16-year period from 1980 to 1995. A total of 320 patients were identified from the Meningococcal Research Database, which comprises information from the following sources: (i) the Department of Public Health, to whom notification of meningococcal disease is obligatory; (ii) the Regional Hospital Discharge Registry; and (iii) the register of the regional department of clinical microbiology. In order to assess prognostic indicators assessable at admission, information was collected for each patient from hospital records regarding contacts, symptoms and signs on arrival, laboratory data, and course of disease. The mean incidence was 4.3 cases per 100 000 persons per year (range, 2.7–7.7). The incidence increased slightly during the period studied. Overall, the case fatality rate was 9.7%, with a significant rise occurring during the period (P=0.016) and a peak occurring in 1992. Advanced age (≥50 years), seizures, impaired consciousness, and skin bleeding on arrival at hospital were predictors of death.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 4 (1985), S. 299-303 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A rapid immunoelectrophoretic assay was developed to detect antibodies toAspergillus fumigatus catalase. The method's diagnostic sensitivity for pulmonary aspergillosis was 88 % (72–97 %, 95 % confidence limits) in 33 patients presenting with either aspergilloma orAspergillus lung infiltrate. The diagnostic specificity was 94 % (90–97 %) as judged from 191 patients with other infiltrative lung diseases, including infections and neoplasia. None of the 185 healthy subjects had catalase antibodies. The highest titres (ranging up to 256) were found in aspergillosis patients with cavitary lesions. Catalase antibody titres increased in two patients with concomitant development of lung cavities and mycetomas. In patients with resected or stableAspergillus lung disorders catalase antibody titres declined by less than one dilution step per year.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical microbiology & infectious diseases 7 (1988), S. 40-44 
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Seven to ten percent of patients with cystic fibrosis had serum antibodies to the catalase antigen ofAspergillus fumigatus in three cross-sectional surveys between 1977 and 1984. A total of 208 patients participated at least once, and the cumulated frequency of catalase antibodies in 94 patients included in all three surveys was 16 %. The titer range was 1 to 16. The prevalence rate ofAspergillus fumigatus in sputum was 50 % for a 2.5-year observation period. Catalase antibodies were strongly associated with the occurrence ofAspergillus fumigatus in sputum (p=0.003), and the microorganism was more numerous in colonized patients with catalase antibodies than in those without such antibodies (p=0.004). Patients withAspergillus fumigatus in sputum and a positive catalase antibody test tended to have an adverse development as regards lung function compared to both carriers without antibodies and non-carriers. The observed differences could not, however, be related to different rates of chronicPseudomonas aeruginosa infection.
    Type of Medium: Electronic Resource
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