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  • 1
    Electronic Resource
    Electronic Resource
    Contact urticaria due to aescin (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 37 (1997), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1997.tb02440.x
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  • 2
    Electronic Resource
    Electronic Resource
    Helicobacter pylori increases the risk of upper gastrointestinal bleeding in patients taking low-dose aspirin (2002)
    Oxford UK : Blackwell Science Ltd.
    Alimentary pharmacology & therapeutics 16 (2002), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To evaluate the role of Helicobacter pylori infection and other clinical factors in the risk of upper gastrointestinal bleeding in patients taking low-dose aspirin.〈section xml:id="abs1-2"〉〈title type="main"〉Subjects and methods:A case–control study was carried out of consecutive current users of low-dose aspirin admitted because of upper gastrointestinal bleeding. Within a cohort of 695 patients with upper gastrointestinal bleeding, 98 patients had taken low-dose aspirin and no other non-steroidal anti-inflammatory drug. Controls were 147 low-dose aspirin users without upper gastrointestinal bleeding of similar age, sex and extent of aspirin use as cases. H. pylori infection was determined by CagA/VacA serology and 13C-urea breath test in all cases and controls. Adjusted odds ratios (OR) are provided.〈section xml:id="abs1-3"〉〈title type="main"〉Results: H. pylori infection was identified as an independent risk factor of upper gastrointestinal bleeding in this population (OR, 4.7; 95% confidence interval (95% CI), 2.0–10.9), but the presence of CagA-positive serology was not. Other risk factors identified were a previous ulcer history (OR, 15.2; 95% CI, 3.8–60.1), alcohol use (OR, 4.2; 95% CI, 1.7–10.4) and use of calcium channel blockers (OR, 2.54; 95% CI, 1.25–5.14). Antisecretory therapy (OR, 0.1; 95% CI, 0.02–0.3) and nitrovasodilators (OR, 0.2; 95% CI, 0.1–0.6) decreased the risk of bleeding.〈section xml:id="abs1-4"〉〈title type="main"〉Conclusions: H. pylori infection is a risk factor for upper gastrointestinal bleeding in low-dose aspirin users, which might have therapeutic implications in high-risk patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2002.01230.x
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  • 3
    Electronic Resource
    Electronic Resource
    Risk of upper gastrointestinal bleeding in patients taking low-dose aspirin for the prevention of cardiovascular diseases (2002)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 16 (2002), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Most patients with vascular-occlusive diseases benefit from low-dose aspirin (75–325 mg/day). However, they have an increased risk of upper gastrointestinal bleeding (UGIB).Aims : To analyse the incidence and factors influencing the occurrence of UGIB in patients taking low-dose aspirin for the prevention of cardiovascular diseases outside clinical trials.Methods : We studied 903 consecutive patients discharged on low-dose aspirin from the Cardiology Department of a general hospital. Data were collected from medical charts and structured telephone interviews.Results : Forty-one patients (4.5%) presented with UGIB requiring hospitalization during follow-up (45 ± 22 months). The incidence of UGIB was uniform during follow-up (1.2 UGIB per 100 patient years). Multivariate analysis showed that a history of peptic ulcer or UGIB [risk ratio: 3.1, 95% CI: (1.5–6.5)] and aspirin dose (per 100 mg/day) [1.8 (1.5–2.9)] was associated with higher risk of UGIB. On the other hand, antisecretory [0.22 (0.07–0.75)] and nitrovasodilator drugs [0.73 (0.55–0.96)] were associated with a decreased risk.Conclusions : Cardiovascular patients on long-term low-dose aspirin have a stable risk of major UGIB, which is higher than published controlled clinical trials. Antisecretory and nitrovasodilator drugs protect from UGIB, whereas previous peptic ulcer or UGIB and higher doses of aspirin increase the risk.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2002.01355.x
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  • 4
    Electronic Resource
    Electronic Resource
    Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin (2005)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 22 (2005), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Aspirin is valuable for preventing vascular events, but information about ulcer frequency is necessary to inform risk-benefit decisions in individual patients.Aim : To determine ulcer prevalence and incidence in a population representative of those given aspirin therapy and evaluate risk predictors.Methods : Patients taking aspirin 75–325 mg daily were recruited from four countries. Exclusions included use of gastroprotectant drugs or other non-steroidal anti-inflammatory drugs. We measured point prevalence of endoscopic ulcers, after quantitating dyspeptic symptoms. Incidence was assessed 3 months later in those eligible to continue (no baseline ulcer or reason for gastroprotectants).Results : In 187 patients, ulcer prevalence was 11% [95% confidence interval (CI) 6.3–15.1%]. Only 20% had dyspeptic symptoms, not significantly different from patients without ulcer. Ulcer incidence in 113 patients followed for 3 months was 7% (95% CI 2.4–11.8%). Helicobacter pylori infection increased the risk of a duodenal ulcer [odds ratio (OR) 18.5, 95% CI 2.3–149.4], as did age 〉70 for ulcers in stomach and duodenum combined (OR 3.3, 95% CI 1.3–8.7).Conclusions : Gastroduodenal ulcers are found in one in 10 patients taking low-dose aspirin, and most are asymptomatic; this needs considering when discussing risks/benefits with patients. Risk factors include older age and H. pylori (for duodenal ulcer).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2005.02649.x
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  • 5
    Electronic Resource
    Electronic Resource
    Contact urticaria from sunflower seeds (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 37 (1997), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1997.tb00198.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Acute urticaria after ingestion of asparagus (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 53 (1998), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1998.tb03942.x
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  • 7
    Electronic Resource
    Electronic Resource
    Perianal disease of tuberculous origin (1999)
    Springer
    Diseases of the colon & rectum 42 (1999), S. 110-112 
    Details
    ISSN: 1530-0358
    Keywords: Perianal tuberculosis ; Perianal ulcers ; Extrapulmonary tuberculosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: A case of anal tuberculosis in an otherwise asymptomatic patient with bleeding anal ulcers is presented. The clinical features of this entity and the problems in differential diagnosis between anal infectiousvs. inflammatory diseases are discussed. METHODS: The management and outcome of the case of an adult patient who presented with perianal ulcers is described. RESULTS: On a three-drug antituberculous regimen, symptoms abated, radiographic infiltrates improved, and perianal ulcers healed. CONCLUSION: Anal tuberculosis is an extremely rare disease. A tuberculous origin must be considered when the cause of perianal ulcers is unclear to avoid undesirable delays in the diagnosis and treatment of this disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02235192
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  • 8
    Electronic Resource
    Electronic Resource
    Structural and seasonal variations of inshore fish populations in Málaga Bay, Southeastern Spain (1987)
    Springer
    Marine biology 95 (1987), S. 501-508 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A seasonal study of the inshore fish community was conducted in 1981 and 1982 at two stations in Málaga Bay (SE Spain). A total of 66 fish species were caught. Two families, Clupeidae (68.6%) and Engraulidae (28.5%), dominated in numbers, and Carangidae (54.3%) and Sparidae (29.1%) in biomass for both zones. There were two periods of high fish density in each zone: winter (2.2 g m-2) and autumn (2.0 g m-2) in the western zone and spring (2.95 g m-2) and summer (3.6 g m-2) in the eastern zone. Species diversity was relatively high during spring (2.95 and 3.00) and summer (2.32 and 2.44), showing clear variation with other zones of the Spanish coasts. An increase in diversity and number of fish species from north to south was observed. The area studied (0 to 15 m deep) serves as a nursery for larvae and young fish of several species appearing in the catches. The zoogeographical affinities of the fish species caught are: tropicals 25.7%, boreals 24.2%, Iberian-Moroccan 14%, endemics 4.5%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00393093
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  • 9
    Electronic Resource
    Electronic Resource
    Esophageal obstruction by solidification of the enteral feed: a complication to be prevented (1997)
    Springer
    Intensive care medicine 23 (1997), S. 790-792 
    Details
    ISSN: 1432-1238
    Keywords: Key words Sucralfate ; Esophageal obstruction ; Enteral nutrition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report three cases of esophageal obstruction due to solidification of enteral feed refluxed from the stomach in patients being fed through a nasogastric tube. All three patients were administered sucralfate continuously by tube. The few previous descriptions of this rare complication have also implicated sucralfate with its pathogenesis. Given its clinical importance and the growing use of long-term enteral nutrition, this adverse event needs to be considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050412
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  • 10
    Electronic Resource
    Electronic Resource
    Intrinsic Innervation of the Chicken Lower Digestive Tract (1997)
    Springer
    Neurochemical research 22 (1997), S. 1425-1435 
    Details
    ISSN: 1573-6903
    Keywords: Enteric nervous system ; cholinergic innervation ; catecholaminergic innervation ; peptidergic innervation ; ultraestructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have studied the different components of the enteric nervous system in the rectum and cloaca of the chicken by means of hystochemical and immunohistochemical techniques. We found cholinergic neuronal bodies as well as nervous fibers, which constitute part of the Meissner and Auerbach plexuses. We also observed plentiful catecholaminergic fibers in both plexuses, though there were no catecholaminergic neuronal bodies. With respect to the Vasoactive Intestinal Peptide (VIP) and substance P (SP) positive peptidergic innervation, only positive fibers were found, which were less abundant than in the other zones of the gastrointestinal tract. The optic microscopy results were confirmed by electron microscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1021990025420
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