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  • 1
    Electronic Resource
    Electronic Resource
    Oxford BSL : Blackwell Science Ltd
    British journal of dermatology 140 (1999), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2307
    Keywords: CD44 variant isoforms ; Skin ; Basal cell carcinoma ; Spindle cell carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Splice variants of the adhesion molecule CD44 (CD44v) are important in the lymphatic spread of rat carcinoma cells. In several human tumours expression of CD44v correlates with tumour progression. However, little is known about the physiological functions of distinct variant exons. Here we report on the immunohistological evaluation of CD44 expression in normal human skin and epidermal tumours which do not metastasise, or do so vary rarely. Frozen tissues were stained with a panel of monoclonal antibodies, recognizing epitopes of the CD44 standard isoform, as well as of variant exons v5, v6, v7, v7–v8 and v10. Stratum basale and spinosum as well as the root shaft of hairs reacted strongly with the whole panel of anti-CD44 antibodies. Stratum corneum, acinar cells of sebaceous and eccrine sweat glands stained with anti-CD44v5, anti-CD44v6 and anti-CD44v7, but not with anti-CD44v10, the latter recognizing the “epithelial isoform” (CD44v8–v10) of CD44. Ductal cells of glands and apocrine glands did not express CD44v. Compared with its expression in normal human skin, CD44v expression was reduced in basal cell carcinoma and squamous cell carcinoma of the skin. This was particularly true of CD44v10. The expression of CD44v in normal skin and dermal appendages indicates that not all combinations of variant exons are involved in tumour progression. Since the epithelial isoform is particularly downregulated in basal cell carcinoma and squamous cell carcinoma of the skin, it is unlikely that exons v8–v10 play a role in tumour progression. Rather, they may be of functional importance in maintenance of the epidermal structure.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Biology and fertility of soils 30 (1999), S. 61-68 
    ISSN: 1432-0789
    Keywords: Key words Alley cropping ; 15N injection ; Nitrogen recovery ; Alnus sinuta ; Green manure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract  Nitrogen (N) fluxes through the major plant pools of an alder (Alnus sinuta)-sweet corn (Zea mays) alley cropping system were determined over the course of two cropping seasons. Alder trees were injected with 15NO3–N to directly follow the flow of N between alder and corn. The contribution of the above- and below-ground tree N to corn was determined by exchanging the labeled above-ground prunings (green manure) with those from unlabeled plots. During the first growing season after coppicing of the injected alders, 18% of the alder 15N was taken up by the corn with 12% coming from the above-ground prunings. Of the 15N remaining in the tree/stump following coppicing, the majority was recovered by corn plants within the rows next to the labeled trees during the first growing season. Earlier recovery of 15N by corn in the labeled root plots compared to the labeled pruning plots indicated the importance of root turnover in supplying N to corn, especially following coppicing. By the end of the first and second growing seasons, 34% and 38% of the 15N initially present in prunings was recovered in corn plants, respectively. Approximately 80% of the total injected 15N was found in the soil during the second growing season; however, the turnover of above- and below-ground alder components supplied only 3–4% of the N required by corn during the year of green manure application. Thus, most of the corn N demand was met by mineralization of residual soil N within the 2 years of coppicing and green manure additions. Continued internal cycling of tree N and movement of soil N into more labile pools would presumably allow more alder N to become available over time. The synchronization between N mineralization from the hedgerow green manure components and nutrient uptake of the alley crop remains a major challenge in alley cropping and other green manure systems.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1572-9680
    Keywords: A,nus rubra ; hedgerow intercropping ; Robina pseudoacacia ; Zea mays
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The objective of this study was to determine crop and tree productivity in several alley cropping planting patterns. The four- year study was conducted in western Oregon, United States and involved irrigated sweet corn (Zea mays) intercropped between hedgerows of red alder (Alnus rubra) and black locust (Robina pseudoacacia). Three alley cropping planting patterns with variable plant populations and tree-crop proximity were tested with each tree species in a randomized block design. Space available to trees and crops determined yield of both plant components. High crop yield coincided with low pruning yield, and vice versa. Compared to monocropping, yield reductions in traditional alley cropping planting patterns with widely spaced, double tree rows ranged from 5% to 15%. A. rubra and R. pseudoacacia coppiced readily and produced 0.9 to 4.7 tons of dry matter pruning biomass per growing season, depending on planting pattern and year. A. rubra yield continually increased during the trial, while the ability of R. pseudoacacia to produce green manure after frequent coppicing appeared to weaken. After four years, soil organic matter was 4 to 7% higher in the topsoil of an alley cropping system compared to a monocropping system. However, continuous growing of sweet corn resulted in decreased soil organic matter levels in both cropping systems compared to original levels. Crop yield reductions and the need for additional management inputs constrain the implementation of alley cropping in temperate climates. Only if benefits other than minor soil fertility improvements are realized is alley cropping a feasible alternative in temperate climate regions.
    Type of Medium: Electronic Resource
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