Electronic Resource
Springer
Veterinary research communications
18 (1994), S. 367-372
ISSN:
1573-7446
Keywords:
caffeine
;
horse
;
liver function
;
pharmacokinetics
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The pharmacokinetic properties of intravenously administered caffeine were studied in 10 horses using a commercially available automated enzyme immunoassay. The harmonic mean for the distribution half-life was 5.2 min (range 1.4–18.7). The harmonic mean for the elimination half-life was 10.18 h (range 6.82–20.92). The harmonic mean of the volume of distribution was 0.32 L/kg (range 0.22–0.53). There was no correlation between the dose of caffeine/kg body weight and the elimination half-life (Spearman's coefficient of rank correlation =0.19).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01839287
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