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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 61 (1957), S. 1449-1450 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 61 (1957), S. 1450-1451 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 71 (1967), S. 453-454 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 98 (1994), S. 5742-5743 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 69 (1994), S. 154-158 
    ISSN: 1439-6327
    Keywords: Neuromuscular fatigue ; Optimal pedalling rate ; Integrated electromyogram
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of this study was to estimate the differences in neuromuscular fatigue among prolonged pedalling exercises performed at different pedalling rates at a given exercise intensity. The integrated electromyogram (iEMG) slope defined by the changes in iEMG as a function of time during exercise was adopted as the measurement for estimating neuromuscular fatigue. The results of this experiment showed that the relationship between pedalling rate and the means of the iEMG slopes for eight subjects was a quadratic curve and the mean value at 70 rpm [1.56 (SD 0.65) μV·min−1] was significantly smaller (P 〈 0.01) than that at 50 and 60 rpm [2.25 (SD 0.54), and 2.22 (SD 0.68), respectively]. On the other hand, the mean value of oxygen consumption obtained simultaneously showed a tendency to increase linearly with the increase in pedalling rate, and the values at 70 and 80 rpm were significantly higher than those at 40 and 50 rpm. In conclusion, it was demonstrated that the degree of neuromuscular fatigue estimated by the iEMG changes for five periods of prolonged pedalling exercise at a given exercise intensity was different among the different pedalling rates, and that the pedalling rate at which minimal neuromuscular fatigue was obtained was not coincident with the rate at which the minimal oxygen consumption was obtained, but was coincident with the rate which most subjects preferred. These findings would suggest that the reason why most people prefer a relative higher pedalling rate, even though higher oxygen consumption is required, is closely related to the development of neuromuscular fatigue in the working muscles.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 65 (1992), S. 335-339 
    ISSN: 1439-6327
    Keywords: Muscle fatigue ; Integrated electromyogram ; Maximum oxygen uptake ; Electromyogram break point ; Oxygen uptake response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The surface electromyogram (EMG) from active muscle and oxygen uptake ( $$\dot VO_2 $$ ) were studied simultaneously to examine changes of motor unit (MU) activity during exercise tests with different ramp increments. Six male subjects performed four exhausting cycle exercises with different ramp slopes of 10, 20, 30 and 40 W · min−1 on different days. The EMG signals taken from the vastus lateralis muscle were stored on a digital data recorder and converted to obtain the integrated EMG (iEMG). The $$\dot VO_2 $$ was measured, with 20-s intervals, by the mixing chamber method. A non-linear increase in iEMG against work load was observed for each exercise in all subjects. The break point of the linear relationship of iEMG was determined by the crossing point of the two regression lines (iEMGbp). Significant differences were obtained in the exercise intensities corresponding to maximal oxygen uptake ( $$\dot VO_{2 max} $$ ) and the iEMGbp between 10 and 30, and 10 and 40 W · min −1 ramp exercises (P 〈 0.05). However, no significant differences were obtained in $$\dot VO_{2 max} $$ and $$\dot VO_2 $$ corresponding to the iEMGbp during the four ramp exercises. With respect to the relationship between $$\dot VO_2 $$ and exercise intensity during the ramp increments, the $$\dot VO_2 $$ -exercise intensity slope showed significant differences only for the upper half (i.e. above iEMGbp). These results demonstrated that the $$\dot VO_{2 max} $$ and $$\dot VO_2 $$ at which a nonlinear increase in iEMG was observed were not varied by the change of ramp slopes but by the exercise intensity corresponding to $$\dot VO_{2 max} $$ and the iEMGbp was varied by the change of ramp slopes. In addition, the significant differences in the $$\dot VO_2 $$ exercise intensity slopes for the upper half of the tests would suggest that the recruitment patterns of MU and/or muscle metabolic state might be considerably altered depending upon the ramp slope increments.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The structures of kikumycin A and B, antiviral amidine antibiotics, have been elucidated by means of low and high resolution mass spectrometry. Amino acid composition and their sequences were also clearly demonstrated by this technique. The evidence for the fragmentation of terminal amidines or amides of kikumycin derivatives and related synthetic compounds was represented by the elimination of ammonia or water from the molecular ions to give stable nitrile ions. Additionally, the participation of the iminol structure in the pyrrole-2-carboxamide portion of kikumycin A and B was confirmed by the fragment ions derived from their iminol tautomers.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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