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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Water and environment journal 13 (1999), S. 0 
    ISSN: 1747-6593
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: The enhanced chemiluminescence test is based upon monitoring the emission of light from an enhanced chemiluminescence reaction in the presence of an environmental sample and comparing it with a similar reaction using a de-ionized water control sample. The presence of polluting materials can be detected by changes in the intensity and the kinetics of light emission. This trial demonstrated that the effects of components within a sewage-works' effluent are detected by enhanced chemiluminescence and that this test has moderately close correlation with parallel bacterial determinations. A high correlation was achieved between the performances of two commercially available enhanced chemiluminescence reagents, and these reagents responded consistently to the effects of a sewage-works' effluent on the quality of a small river.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Hypophosphatasia is an inherited disorder characterized by defective mineralization of the skeletal and dental structures of the body and deficient liver/bone/kidney alkaline phosphatase (L/B/K ALP) activity. There has been a tremendous advance in our knowledge of this condition over the last decade due to the advent of highly specific DNA probes and novel microanalytic techniques. The purpose of this paper is threefold: to review the dental aspects of current literature about this rare condition; to present a case (and family study) that was diagnosed in a 5-yr-old boy from 0.14 μl of gingival crevicular fluid, using a new ultrasensitive chemiluminescent assay for the enzyme alkaline phosphatase; and to provide strong evidence for an autosomal dominant mode of inheritance.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The search for markers of periodontal disease activity and progression has accelerated over the last decade, in an effort to replace existing subjective clinical measures of periodontal health status. Research is being aimed at establishing more objective and quantitative methodology, capable of rapid diagnosis prior to the appearance of clinical signs of destructive disease. Such tests need to be sensitive enough to evaluate individual periodontal sites in health as well as disease states. We report the development of a new chemiluminescent assay for the enzyme alkaline phosphatase, that is capable of quantifying the enzyme in sub-microliter volumes of gingival crevicular fluid and serum. The technique will measure alkaline phosphatase (ALP) whilst immobilised on paper strips, without the need for an elution stage. It is simple, versatile and amenable to chair-side use. We discuss in detail the assay procedure and have examined levels of ALP in 11 adult volunteers with clinically healthy periodontal tissues. The mean ALP concentration was 2135 IU/L for GCF and 183 IU/L for serum, a 12-fold difference. There also appeared to be an “oral pattern” of enzyme distribution in healthy periodontal sites, with levels being higher in the anterior region of the mouth and highest in the lower anterior region.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 257 (1975), S. 443-443 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Oceanic Circulation MR. CROLL'S statement (vol. xii, p.494), that the North Atlantic in lat. 38 is above the level of the equator, is based partly on the Challenger soundings and partly on Muncke's determinations of the thermal expansion of sea-water, which, however, were not made on sea-water at ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Analytica Chimica Acta 249 (1991), S. 263-269 
    ISSN: 0003-2670
    Keywords: Clinical test devices ; Disposable analytical devices ; Immunoassay ; Printed liquidic circuits ; Switch devices
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Analytica Chimica Acta 249 (1991), S. 263-269 
    ISSN: 0003-2670
    Keywords: Clinical test devices ; Disposable analytical devices ; Immunoassay ; Printed liquidic circuits ; Switch devices
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 12 (1875), S. 514-514 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] MR. CROLL's statement (vol. xii. p. 494), that the North Atlantic inlat. 38° is above the level of the equator, is based partly on the Challenger soundings and partly on Muncke's determinations of the thermal expansion of sea-water, which, however, were not made on sea-water at all, but on a ...
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Using a recently developed chemiluminescent assay enabling alkaline phosphatase (ALP) quantification in nanolitre volumes of gingival crevicular fluid (GCF), we have investigated GCF ALP levels in health and in the presence of gingivitis. In gingival health, there was a site-specific pattern of ALP concentration with higher enzyme concentrations around the upper and lower anterior teeth. Furthermore, clinically normal sites that had been subjected to different levels of plaque control produced significantly different ALP levels, (p 〈 0.03). This indicates that biochemical components of GCF may be used to measure sub-clinical inflammatory status. The ratio of GCF to serum ALP varied from 6:1 to 11:1, suggesting that a major source of the enzyme is through local production. The main cross-sectional study of 30 patients with gingivitis (276 sites) demonstrated that total GCF ALP levels, collected over a 30-s sampling time were higher for a gingival index of 1 than of 0 (p 〈 0.014). There was no significant relationship between total GCF ALP and plaque levels of the enzyme, and analysis of plaque within the study group demonstrated very low levels of ALP, indicating that the enzyme is likely to be largely derived from the periodontal tissues. The ratio of GCF ALP levels to those of saliva within individuals was 530:1, thereby eliminating saliva contamination as a risk, when total GCF ALP is being measured.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Forschung im Ingenieurwesen 65 (2000), S. 301-308 
    ISSN: 1434-0860
    Source: Springer Online Journal Archives 1860-2000
    Topics: Technology
    Description / Table of Contents: Zusammenfassung  Dieser Artikel beschreibt den numerischen Lösungsalgorithmus, der für die Untersuchung des Wärmeübergangs mit zweidimensionaler freier Konvektion in nicht-rechtwinkliger Umrandung eingesetzt wird. Der Impulstransport im System wird durch eine elliptische, partielle Differentialgleichung beschrieben. Eine algebraische Netzgenerierungsmethode wird für die Transformation des beschreibenden Differentialgleichungssystems in ein rechtwinkliges Koordinatensystem verwendet. Numerische Lösungen der resultierenden Gleichungen im Berechnungsgebiet wurden durch Verwendung einer speziellen impliziten Methodik ermittelt. Die erhaltenen Ergebnisse werden exemplarisch anhand der Verläufe von Stromlinien und Isothermen graphisch dargestellt.
    Notes: Abstract  This paper describes a numerical solution procedure to study heat transfer process by two dimensional natural convection phenomena in a non-rectangular enclosure of arbitrary geometry. Momentum transfer in the system is described by an elliptic partial differential equation, which governs the behaviour of the stream function. An algebraic grid generation technique is used to transform the governing equations into a body fitted rectangular co-ordinate system that allows coincidence of all boundary lines with the co-ordinate lines. Numerical solutions of the resulting equations in the computational domain are obtained using an alternating directional implicit method by adding false transient terms. Results from the numerical experiments in the case of a non-rectangular enclosure are obtained that show the magnitude and directions of convection currents and contours of the temperature. The effect of increase in the inclination of the upper boundary is to increase the average Nusselt number.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Heat and mass transfer 35 (1999), S. 39-48 
    ISSN: 1432-1181
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract A numerical study is performed to analyse heat and mass transfer phenomena due to natural convection in a composite cavity containing a fluid layer overlying a porous layer saturated with the same fluid. The flow in the porous region is modelled using Brinkman–Forchheimer-extended Darcy model that includes both the effect of macroscopic shear (Brinkman effect) and flow inertia (Forchheimer effect). The vertical walls of the two-dimensional enclosure are isothermal whilst the horizontal walls are adiabatic. The two regions are coupled by equating the velocity and stress components at the interface. The resulting coupled equations in non-dimensional form are solved by an alternating direction implicit method by transforming them into parabolic form by the addition of false transient terms. The numerical results show that the amount of fluid penetration into the porous layer depends strongly upon the Darcy, thermal and solutal Rayleigh numbers. Average Nusselt number decreases while average Sherwood number increases with an increase of the Lewis number. The transfer of heat and mass on the heated wall near the interface depends strongly on the Darcy number.
    Type of Medium: Electronic Resource
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