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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 3859-3863 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The high power ion beams used in the next generation thermonuclear fusion reactors require high current negative ion beams accelerated to high energy, with high efficiency. One way to meet these requirements is to merge multiple low current density H− beamlets into a single high current beam. The feasibility of a high current merging preaccelerator was demonstrated in this experiment by merging 19 beamlets of H− ions distributed over a circular area 80 mm in diameter from a Japan Atomic Energy Research Institute negative ion source. H− ions were extracted at a current density exceeding 10 mA/cm2 at the ion source which operates at 0.13 Pa (1 mTorr), with a low arc power density (70 V×250 A). Spherically curved grids (with built-in magnetic electron suppression) were used in the preaccelerator to focus the extracted beamlets into a single 104 mA, 100 keV beam. The merged beam has a diameter of 23 mm and a converging angle of ±30 mrad at the beam envelope. The rms emittance of the 104 mA merging beam was 1.00 π mrad cm, which is a condition acceptable to the electrostatic quadropole accelerator for further acceleration. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Neutral beams for the next generation tokamaks will be based on multiampere negative ion beams with a beam energy of about 1.0 MeV and pulse lengths of a thousand seconds. High intensity dc beams at these levels of beam energy will require extensive development in electrostatic accelerators. At Lawrence Berkeley Laboratory, a two-module electrostatic quadrupole (ESQ) accelerator was built to accelerate ions to 200 keV. In this experiment, up to 100 mA of H− beam current was obtained from a Japan Atomic Energy Research Institute cesiated volume source using a multiaperture preaccelerator which merged 19 beamlets into a single circular beam at the entrance to the ESQ accelerator. The H− beam was accelerated by the ESQ to accelerate 200 keV without any significant beam loss or emittance growth. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 59 (1988), S. 2357-2365 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The U. S. magnetic fusion energy program has developed a single design, long-pulse neutral beam source for TFTR, MFTF-B, and DIII-D. The arc is a very compact axial magnetic line cusp. The accelerator is an actively cooled tetrode with water-cooled grid tubes of shaped molybdenum forming "slot'' beamlets. DIII-D and MFTF-B configurations have an 80-kV accelerator gap, with a 12×18 cm aperture, and a 10-m "module'' focus. TFTR modules are unfocused, with a 120-kV gap and 12×43-cm mask. The first CLPS was tested in the TFTR configuration, at 120 kV, 2s. Optimum current was 73 A, or 1.76 μpervs (deuterium), with 80%–85% atomic fraction. Optimum divergence of ions plus neutrals was 0.4° parallel to the slots, and 0.7° perpendicular to the slots (1/e half-angle). The combination of an axial cusp magnetic bucket and slot accelerator apertures gives the common long pulse source about twice the beam power per unit cross section of other long pulse sources, plus lower divergence in the direction parallel to the slots.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 2714-2719 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The 10×40-cm long pulse neutral beam source developed at Lawrence Berkeley Laboratory has been selected as the prototype for the design of the U. S. common long pulse source to be used on tokamak fusion test reactor (TFTR), Doublet-III, and mirror fusion test facility (MFTF-B). The long pulse source consists of a magnetic line cusp bucket with an actively cooled backplate electron dump and a four-grid accelerator using slot apertures and water-cooled molybdenum rails. Deuterium testing of the long pulse source at 120 kV and 53 A and with a 2-s pulse length has been completed on the neutral beam engineering test facility, including an 8-h 100-shot test to demonstrate the durability and reliability of the source. Maximum 2-s beam parameters obtained (not simultaneously) are 125 kV, 58 A (deuterium), and 7.1 MW. Beam pulse length has been extended to 5 s at 120 kV. Atomic species fractions in excess of 80% have been obtained, with a beam divergence (full energy, 1/e half-angle) of approximately 0.8×0.4°. Calorimetric measurements on the accelerator grids and backplate electron dump indicate heat loads consistent with predictions and within the design limits of the source. This testing has verified the design of the source and its ability to exceed the basic performance requirements.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 1261-1265 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Beam extraction tests at energies up to 80 kV were performed using a radio frequency induction (RFI) plasma generator hydrogen ion source. A 7×10-cm2, long pulse accelerator was operated with a 10×10-cm2 axial magnetic cusp bucket and a magnetic-filter bucket. Atomic fractions (up to 85% H+), plasma production efficiencies (≈0.6 A of beam per kW rf power), and beam divergence were at least as good as with arc plasmas in similar chambers. Potential advantages of the RFI plasma sources for large-scale applications are ease of operation, reliability, and extended service life.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 2705-2713 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Users of fusion devices have identified heating requirements for positive ion based neutral beams to include energies of 80 or 120 kV with pulse length up to 30 s. Additional requirements are low beam divergence (0.3°×1.0°; 1/e half angles), low impurity (less than 1%), high species (over 80% atomic), and cathode lifetime exceeding 5 h of beam operation. Accelerator design remains as an engineering problem, whereas most of the performance goals have required development of the plasma generator. Problems of concern which relate to the performance goals are the heat dissipation, magnetic field configuration, and cathode placement. The plasma generator was tested on TS IIA (the plasma generator testing facility) which does not have beam extraction capability but is used to evaluate efficiency, operating conditions, arc notching characteristics, species, plasma uniformity, and cathode conditioning. The source, consisting of the plasma generator mounted on the long pulse accelerator was mounted on NBETF (Neutral Beam Engineering Test Facility) for beam testing. During beam operation the back-streaming electrons add power to the source and affect the arc operation. Source durability and stability were studied at 80 kV and 40 A of accelerator current (deuterium). The arc efficiency was higher than the value used for the design. Power loading from back-streaming electrons was much less than the design level. With feedback control, plasma density and accel current were constant to ±2% during 30-s shots. The beam atomic fraction of 84%–88% (deuterium) was slightly higher than measured on TS IIA. Cathode durability was tested by operating over 500, 30-s full shots at 80 kV and 40 A of deuterium. Arc conditioning was found to be an important phase to avoid filament damage.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 43 (1977), S. 277-282 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The trochid snail Monodonta articulata Lamarck was exposed to mercuric sulphate at concentrations of 0.2, 0.5, 0.8 and 1 ppm Hg++. At 24 h, retraction into the shell was observed in 0.8 and 1 ppm Hg++; this retraction increased in these concentrations at 36 h. Retracted snails died if retained in the solutions, but generally recovered within 24 to 48 h if transferred to uncontaminated sea water. Immersionemersion behaviour and interface activity were studied over 24 h by means of an aktograph; snails in normal sea water spent more time below than above the water surface, and exhibited frequent periods of activity. Exposure to mercuric sulphate at concentration of 0.25, 0.5, 0.8 and 1 ppm Hg++ progressively reduced both the length and frequency of activity periods. From 0.5 ppm Hg++ upwards, emersion periods increased, and immersion periods decreased. Oxygen consumption of snails was measured in sea water and in mercuric sulphate at concentrations of 0.2, 0.5, 0.8 and 1 ppm Hg++. Oxygen consumption decreased significantly with each progressive rise in mercury concentration. It is considered that mercury affects M. articulata by interfering with respiration, initially reducing interface activity, then forcing the snail for longer and longer periods out of the water. Retraction occurs when activity is no longer possible. It is concluded that respiratory and behavioural alterations of this nature would afford a good indicator of the presence of sub-lethal concentrations of pollutants.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0428
    Keywords: Insulin gene ; apoprotein genes ; hypertriglyceridaemia ; diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two gene specific probes have been used to identify polymorphic DNA loci on chromosome 11 close to the insulin and apoprotein A-1 genes in a genetic analysis of hypertriglyceridaemic patients with and without co-existing diabetes. Of the 45 patients studied with both probes, 15 were diabetic of whom nine possessed class 3/3 insulin polymorphism genotypes, compared with none in the non-diabetic group (p〈 0.001; χ2 test). In contrast, an uncommon apolipoprotein A-1 polymorphism was found to be equally distributed in the diabetic and the non-diabetic patients. No co-segregation of these two particular genetic polymorphisms was found in either patient group. The differing associations of the two disease-related polymorphism genotypes in patients with hypertriglyceridaemia with or without co-existing diabetes may possibly reflect differing aetiologies of the hyperlipidaemia.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 31 (1986), S. 201-204 
    ISSN: 1432-1041
    Keywords: hyperlipidaemia ; acipimox ; adverse effects ; plasma glucose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Fifty-two patients with Fredrickson Type IIb or Type IV hyperlipidaemia, in whom diet had not achieved satisfactory lipid levels, completed a double blind randomised study of acipimox versus placebo. The patients were given acipimox, 250 mg three times daily or placebo for a three month period, and plasma lipids and glucose were monitored. The patients receiving acipimox showed a fall in the mean concentration of plasma triglyceride compared to placebo (0.74 mmol/l) and this was most marked in patients whose initial plasma triglyceride levels were greater than 3 mmol/l (1.0 mmol/l, confidence limits 0.18, 1.82). Acipimox was well tolerated, and could be a useful addition to the drugs available for the treatment of patients with hypertriglyceridaemia.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Two alleles identified by DNA restriction fragment length polymorphisms around the apo A-1/C-III and insulin genes have been shown to be associated with Type IV and V hyperlipidaemia. We have genotyped 19 patients with Type III hyperlipidaemia to establish whether this association is also found in the disorder. Our data show that these associations are not responsible for the majority of cases of Type III hyperlipidaemia, but cannot exclude the possibility that a small proportion (〉50%) of cases of Type III are caused by interaction between these alleles and the apolipoprotein E2 phenotype.
    Type of Medium: Electronic Resource
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