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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 26 (1987), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Intracerehral (i.e.) intection of adult mice with lymphocytic choriomeningitis (LCM) virus can result in acute lethal central nervous system (CNS) disease which is the result of the host's thymus-derived lymphocyte (T cell) response against the virus. Whether the specific effector function of the T cell is that of a cytotoxic cell (Tc) or a delayed-type hypersensitivity cell (Ta) is still under debate. We assumed that if Td cells were important in pathogenesis then accessory cells in the brain (specificaily, glass-adhcrent macrophages) might vary with the outcome of i.e. infection. We found that accumulation of macrophages in the brain (washed for meaninges and skull cap) appeared to be independent of the severity of the infection (controlled by the mouse strain as well as the strain and dose of virus used). However, differentiation of macrophages was clearly linked to whether or not the infection caused rapid death. In mice that were destined to survive, mycrophages became large, extensively vacuolated, and phagocytically active. In lethally-infected mice macrophages were small and had poor phagocytic abilities, At present this dichntomy could be viewed as either a cause or a consequence of disease outcome. However. the data are not inconsistent with the hypothesis that Td lymphocytes may be of primary importance in pathogenesis.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 10 (1997), S. 139-151 
    ISSN: 0894-3370
    Keywords: Engineering ; Numerical Methods and Modeling
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: The response of a p-i-n photodetector made from gallium arsenide to both steady-state and transient illumination has been modelled. Both an ensemble Monte-Carlo model and a drift-diffusion model were used, the latter with the choice of two different mobility models. The effects of high intensity steady-state illumination on the field and carrier distributions in the photodetector were calculated, and a comparative study of the models made. The transient response to pulsed illumination has also been calculated and the different results obtained from the models explained. The effect of high illumination on the response speed of the detector has been demonstrated. In addition, an expression for obtaining the photocurrent from the Monte-Carlo simulation, with much reduced statistical noise over the conventional estimate, has been derived and successfully tested. © 1997 John Wiley & Sons, Ltd.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A-2: Polymer Physics 10 (1972), S. 1023-1028 
    ISSN: 0449-2978
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The adsorption behavior on silica of some polystrenes of moderate molecular weight distribution, both singly and in mixtures, has been examined. The adsorption isotherms indicate that, in both a good solvent (trichloroethylene) and under theta conditions, the species of higher molecular weight is preferentially adsorbed at or near full surface coverage, but that the smaller adsorbate has an improved opportunity for adsorption at low surface coverage. The use of tritiated adsorbates substantiate the isotherm data in cyclohexane solution.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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