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  • 1
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Digitalis-like compounds (DLC) are steroidal hormones that are synthesized in, and released from, the adrenal gland, whose regulation may be directed by the hypothalamic-pituitary-adrenal (HPA) axis. Increasing evidence points to antitumour properties of these compounds and we hypothesized that the establishment of tumours in athymic nude mice may be facilitated by an abnormal synthesis or secretion of DLC. To explore this hypothesis, DLC concentrations were determined in the plasma, and in adrenal and hypothalamic tissues of nude compared to normal mice under basal conditions, and 30 min after a stress stimulus (i.p. injection of 100 µl saline) with or without additional adrenocorticotropic hormone (ACTH) 1 µg/per animal. Simultaneously, plasma corticosterone and serum adrenocorticotropic hormone (ACTH) concentrations were analysed. The basal DLC concentrations were similar in the plasma and the hypothalamus of both strains, whereas the basal adrenal DLC concentration was significantly lower in the nude mice compared to normal mice. The stress stimulus induced in normal mice a significant increase in DLC concentrations in the adrenal gland, the plasma and the hypothalamus. However, in nude mice, it caused an increase only in the adrenal gland and the hypothalamus, whereas the plasma DLC concentration was not affected. In both strains, the administration of ACTH in addition to injection stress did not provoke a further increase in DLC concentrations while inducing a significant increase in plasma corticosterone concentration. Regardless of the applied stimulus, the nude mice expressed significant lower DLC concentrations in the adrenal gland and the plasma compared to normal mice. The low basal adrenal DLC concentration in nude mice and their impaired DLC response towards stress- and ACTH stimulation both support an involvement of DLC in tumorigenesis.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nutrition 9 (1969), S. 123-147 
    ISSN: 1436-6215
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 138 (1934), S. 41-51 
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Entomologia experimentalis et applicata 11 (1968), S. 450-454 
    ISSN: 1570-7458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary Principal salivary glands were separated under a stereo-microscope from adult wingless Myzus persicae which had been totally immersed in Feulgen stain. The nuclei were compared in size and shape and then assigned to different gland cells. In this way at least nine different cell types could be differentiated in the principal salivary gland. They have been labelled with letters A to I (see Fig. 1). In the main region there are four A-cells in two pairs, one pair of B-cells with larger nuclei, and the odd C-cell, which has a nucleus about double the size of those in B-cells. On the other side of each gland lobe are one pair of D-cells and one pair of F-cells. Nuclei of E-cells are very small compared with those of G-cells, which are extremely large and show a loose structure. The region of cover cells is composed of five cells (H) with irregularly shaped and weakly staining nuclei, and one odd cell (I) with a circular, intensely stained nucleus. In further studies the different cell types will be determined by specific histochemical reactions with a view to distinguishing different kinds of transmission of plant viruses by aphids.
    Notes: Zusammenfassung Die Hauptspeicheldrüse von Myzus persicae (Sulz.) erwies sich als ein differenziert aufgebautes Organ. An herauspräparierten ganzen Drüsen, die nach Feulgen gefärbt waren, wurden Größe und Form der einzelnen Zellkerne verglichen und auf diese Weise neun verschiedene Drüsenzellen unterschieden.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European food research and technology 4 (1901), S. 57-62 
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Entomologia experimentalis et applicata 13 (1970), S. 153-161 
    ISSN: 1570-7458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary Fixed and sectioned principal salivary glands of Myzus persicae stained with acridine orange at different pH-values (pH 2.6–7.0) were investigated under the fluorescence microscope. There were 4 groups of cells, which differed in their ability to absorb acridine orange (Abb. 1). By histochemical demonstration of different substrates a characterization of those 4 groups was possible: 1. Cells A and F (see Abb. 1) contain much RNA and also much protein, which is distinguished by a high cystine content. 2. Cells B, C and I contain much RNA and protein, but reactions for disulphide groups (cystine) were negative. There was an additional high content of hyaluronic acid. 3. Cells D and E. Besides RNA and protein, PAS-positive and Hale-positive substances were found. Because of the different distribution of the latter two substances in the cell different polysaccharides are assumed. 4. Cells G and H. In the G-cells no considerable amounts of RNA, protein and polysaccharides were found. In the H-cells only a weak PAS-reaction took place. Probably these cells produce no secretion for the saliva. The stylet sheath was Hale- and PAS-positiv; thus the presence of protein could be demonstrated.
    Notes: Zusammenfassung In der Hauptspeicheldrüse von Myzus persicae wurden mit histochemischen Nachweismethoden vier Zellgruppen bestimmt. Diese Zellgruppen ließen sich fluoreszenzmikroskopisch auf Grund ihres Bindungsvermögens für Acridinorange unterscheiden, außerdem durch ihren Gehalt an RNS und verschiedenen Proteinen sowie durch ihren Gehalt an Kohlenhydraten (PAS-Reaktion), Hyaluronsäure und anderen Hale-positiven Substanzen. Die Speichelscheide reagierte auf Nachweise für Kohlenhydrate und Protein positiv.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Entomologia experimentalis et applicata 14 (1971), S. 161-174 
    ISSN: 1570-7458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary Concentrations of potato leaf roll virus (PLRV) which are sufficient for transmission accumulate in Myzus persicae after feeding on infected Physalis floridana in about a week at the latest (Table I, Fig. 1). After a feeding period of 1 or 2 days, sweling of the A/F-nuclei of the salivary glands was observed, which showed a bimodal statistical distribution (Table II, Fig. 2). Prolonged feeding did not markedly alter the degree of swelling. These nuclei swelled to the same extent when aphids were kept for only 8 hours or 3 days on infected P. floridana and then transferred to healthy P. floridana (Table III). The swelling of the nuclei might be due to the presence of virus. This was concluded from experiments in which the aphids were first kept on other hosts (Table IV, Fig. 3–6a), later transferred for a short period to healthy (b) or to infected P. floridana (c) and then retransferred to the original aphid hosts. The swelling of nuclei was observed only with those aphids which had been kept on PLRV-infected P. floridana.
    Notes: Zussamenfassung Nach Übertragungsversuchen kann spätestens nach etwa einer Woche mit übertragungsfähigen Konzentrationen des Kartoffelblattrollvirus (PLRV) in M. persicae gerechnet werden. Schon nach 1- bis 2-tägiger Saugzeit auf PLRV-infizierten P. floridana wurden in den Blattlausspeicheldrüsen Schwellungen der A/F-Kerne ermittelt, die sich in 2-gipfeligen Größenverteilungen äußerten. Längere Saugzeiten änderten die Größenverhältnisse nicht wesentlich, verkürzte Infektionszeiten und anschließendes Saugen auf gesunden Pflanzen beinflußte das Ergebnis ebenfalls kaum. Die gleichen Größenverhältnisse zeigten die A/F-Zellkerne, wenn Blattläuse, die von anderen Wirtspflanzen stammten, 1 Tag auf PLRV-infizierten P. floridana saugten und danach auf die jeweiligen Wirtspflanzen zurückkamen. Dies traf jedoch nicht bei Blattläusen zu, die statt dessen auf gesunden P. floridana saugten. Es wird deshalb angenommen, daß es sich bei diesen Kernschwellungen um Einflüsse des PLRV auf die Blattlausspeicheldrüse handelt.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Entomologia experimentalis et applicata 14 (1971), S. 107-114 
    ISSN: 1570-7458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary The nuclei of the different cell types in the salivary gland of Myzus persicae may show considerable variation in their sizes depending on the hostplants on which the aphids have been reared. This influence of the hostplants has been studied in efforts to elucidate the role of the salivary gland in plant virus transmission. The results are summarized in Fig. 1. The designation of the different cell types is the same as in earlier publications (Weidemann 1968, 1970). It is seen that the extent of nuclear swelling and the type of cells affected by this phenomenon vary depending on the hostplants. The swelling is accompanied by structural changes in the nuclei (Figs 4–6). In view of known relationships between the cell function and nuclear size it is suggested that the hostplant may have an influence on the composition of the saliva of the aphids. This influence could also be responsible for differences in the ability to transmit virus of aphids reared on different hostplants. The kind of structural changes of the nuclei suggests that different mechanisms may be responsible for the nuclear swelling in different cell types.
    Notes: Zusammenfassung Die Volumina der Zellkerne in den Speicheldrüsen von M. persicae sind nicht konstant, sondern variieren je nach Wirtspflanze der Blattlaus. Dabei kann es bei einzelnen Zelltypen zu starken Kernschwellungen kommen. Das Ausmaß der Kernschwellungen und die davon betroffenen Zelltypen können von Wirtspflanze zu Wirtspflanze wechseln. In der Diskussion wird auf die Beziehung zwischen Zellstoffwechsel und Kerngröße hingewiesen und vermutet, daß die Anteile der einzelnen Komponenten in der Speichelflüssigkeit wirtspflanzenabhängig sind. Im Hinblick auf wirtspflanzenabhängige Vektorleistungen der Blattläuse wird die Rolle des Speichels bei der Übertragung phytopathogener Viren diskutiert.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 54 (1967), S. 492-492 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1433-0385
    Keywords: Key words: Mesenteric vascular occlusion ; Vascular surgery ; Mesenteric artery reconstruction. ; Schlüsselwörter: Mesenterialgefäßverschluß ; Mesenterialarterienrekonstruktion ; Gefäßchirurgie.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Bei einer 57 jährigen dialysepflichtigen Patientin mit generalisierter Arteriosklerose trat ein 3-Etagen-Verschluß der Mesenterialarterien mit schnell progredienter Symptomatik auf. Die arteriographische Diagnostik zeigte, daß der gesamte Magen-Darm-Trakt über eine Collaterale aus der A. rectalis superior über die Dick- und Dünndarmarkaden und weiter über die Bühler-Anastomose (pancreaticoduodenale Arkaden) versorgt wurde. Die Revascularisierung erfolgte über die A. mesenterica superior mit Hilfe eines Gore-Tex®-Interponates. Der postoperative Verlauf war durch die schweren internistischen Begleiterkrankungen der Patientin verlängert; chirurgische Komplikationen traten nicht auf, die Symptomatik der Angina abdominalis besserte sich innerhalb weniger Tage. Der Fallbericht zeigt, daß auch bei Patienten mit einem erhöhten Risiko eine Revascularisierung der Mesenterialgefäße durchgeführt werden kann. Eine Einzelgefäßrevascularisation scheint bei der bestehenden Collateralisierung ausreichend.
    Notes: Summary. A 57-year-old patient with general arteriosclerosis and end-stage renal failure was found to be suffering from occlusion of the mesenteric arteries. The symptoms were rapidly progressive. The aortogram showed that nutrition of the whole intestine took place via a collateral vessel that originated at both internal iliac arteries. Revascularization of the superior mesenteric artery with interposition of Gore-Tex prosthesis and transposition to the aorta were performed. The postoperative course was uncomplicated, but prolonged due to the accompanying diseases. In conclusion, single-vessel revascularization for chronic intestinal ischemia is a safe and sufficient procedure. Interpositioning of a graft and transposition to the aorta have the advantages of infrarenal access with an antegrade blood flow and no kinking of the prosthesis.
    Type of Medium: Electronic Resource
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