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  • 1
    Electronic Resource
    Electronic Resource
    Transient decrease of coronary flow reserve in viable postischemic myocardium: Vascular ''stunning''
    Amsterdam : Elsevier
    Journal of Molecular and Cellular Cardiology 19 (1987), S. S23 
    Details
    ISSN: 0022-2828
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0022-2828(87)80077-9
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  • 2
    Electronic Resource
    Electronic Resource
    Determinants of mortality when primary LV failure complicates acute myocardial infarction (1996)
    Springer
    Intensive care medicine 22 (1996), S. S89 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01921263
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  • 3
    Electronic Resource
    Electronic Resource
    An expert system for the labeling and 3D reconstruction of the coronary arteries from two projections (1990)
    Springer
    The international journal of cardiovascular imaging 5 (1990), S. 145-154 
    Details
    ISSN: 1573-0743
    Keywords: quantitative coronary angiography ; knowledge-based systems ; expert systems ; three-dimensional reconstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In this paper we present a rule-based expert system for the automatic delineation and 3D reconstruction of the left coronary artery on standard RAO and LAO angiographic projections. The approach is based on the application of a general blood vessel model and on anatomical models which take into account the normal variations of the coronary artery structure. In a first step, the arteries are delineated by detecting the maximum intensity on the centerline of the vessels. Then, we label the blood vessel segments according to an anatomical model of the left coronary artery. In general, only 1–2 labels remain for each blood vessel segment. Finally, these results are used for an automatic 3D reconstruction of the left coronary artery from two projections. Results from clinical RAO and LAO angiograms will be presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01833983
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  • 4
    Electronic Resource
    Electronic Resource
    A new quantitative method for the analysis of cardiac perfusion tomography (SPET): validation in post-infarct patients treated with thrombolytic therapy (1993)
    Springer
    European journal of nuclear medicine 20 (1993), S. 1193-1200 
    Details
    ISSN: 1619-7089
    Keywords: Perfusion defect ; Infarct size ; Single-photon emission tomography ; Edge detection ; Perfusion tracer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In this study a new method for assessment of perfusion defects (PDs) derived from myocardial perfusion tomograms was evaluated in patients treated with thrombolytic therapy. Using global constraints and dynamic programming, a model-based delineation algorithm defined myocardial borders, the basal plane and absolute and relative PD size in 49 thallium-201 chloride (201TL CL) and 60 technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) tomograms. Tomographic (single-photon emission tomography: SPET) and planar quantification of PDs was compared to enzymatic infarct size as well as to global (LVEF) and regional ventricular function (RWM) obtained by contrast angiography. The algorithm delineated the myocardium and the valve plane in most cases, even when large PDs were present. Manual correction of the automatic delineation of the basal plane was necessary in less than 20% of the studies. Using 201T1 C1, LVEF correlated better with tomographic PD (r=−0.67) than with planar PD (r=−0.54). Comparing planar to tomographic imaging using 99mTc-MIBI, a higher correlation with enzymatic infarct size (r=0.73 vs 0.57) and with global ventricular function (r=−0.64 vs −0.52) was found when tomographic techniques were used. No close correlation between PD and RWM was found. The beneficial effect of thrombolysis was shown by a significant difference of PD in patients with open versus occluded infarct-related vessels. It can be concluded that this new automated algorithm for quantification of SPET perfusion defect size provides a useful tool in evaluating thrombolytic therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00171018
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  • 5
    Electronic Resource
    Electronic Resource
    Double Prosthetic Valve Endocarditis Caused by Streptococcus pneumoniae (2000)
    Springer
    Infection 28 (2000), S. 51-52 
    Details
    ISSN: 1439-0973
    Keywords: Key words Endocarditis ; Streptococcus pneumoniae ; Heart valve prosthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Infective endocarditis (IE) caused by Streptococcus pneumoniae is a rare disease. Only eight cases of pneumococcal prosthetic valve endocarditis have been described in the literature. In this report we describe the first case of pneumococcal endocarditis involving two prosthetic heart valves. The patient had pneumonia as the probable portal of entry but no predisposing conditions for invasive pneumococcal disease. Our case also illustrates the importance of transesophageal echocardiography (TEE) for the early diagnosis of IE and a timely decision for cardiac surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s150100050013
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  • 6
    Electronic Resource
    Electronic Resource
    Autonomic pathways in the orbit of the human fetus and the rhesus monkey (1989)
    Springer
    Documenta ophthalmologica 72 (1989), S. 247-264 
    Details
    ISSN: 1573-2622
    Keywords: autonomic nerves ; pterygopalatine ganglion ; ciliary ganglion ; Tenon's capsule ; tarsal muscle ; orbital muscle ; orbit ; acetylcholinesterase ; histochemistry ; thick section ; human fetus ; monkey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to study the three-dimensional topography of the intra-orbital autonomic nerve plexuses and the input for these systems, human fetuses and adult rhesus monkeys were investigated. Specimens of the orbits were processed according to the histochemical acetylcholinesterase methods for staining of peripheral nerves. The nerve fibers enter the orbit along the following pathways: 1. bundles of nerve fibers from the pterygopalatine ganglion (mainly parasympathetic) by penetrating the orbital muscle (Müller); 2. perivascularly along the ophthalmic artery (sympathetic). In the orbit the nerve fibers intermingle. The pathways of the nerve fibers from this interwoven nerve plexus towards the target organs are: 1. perivascularly along branches of the ophthalmic artery; 2. perineurally along and in the branches of the ophthalmic and maxillary nerves; 3. independently of blood vessels and cranial nerve branches in Tenon's capsule. Moreover, bundles of nerve fibers from the ciliary ganglion contribute to the innervation of extraocular structures, e.g. the eyelids. It can be concluded that, as far as the autonomic innervation of the orbit is concerned, the monkey is a good animal model for neuroanatomical studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00153492
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  • 7
    Electronic Resource
    Electronic Resource
    Willem Vrolik on cyclopia (1991)
    Springer
    Documenta ophthalmologica 77 (1991), S. 355-368 
    Details
    ISSN: 1573-2622
    Keywords: History of ophthalmology ; congenital malformation ; cyclopia ; synophthalmos ; mammal ; human foetus ; neonatus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One of the founders of the Museum Vrolikianum, Professor Willem Vrolik (1801–1862), was very interested in teratology, especially in a congenital malformation termed cyclopia. In 1834 he published a paper on cyclopia. This work was mainly based on studies of cyclopic specimens present in the collection of his father, Professor Gerardus Vrolik. In this study he proposed a classification system for cyclopes, in which he divided them into five main types. This study also formed the basis for the chapters on cyclopia in his Handbook of pathological anatomy (1842–1844) and his Tabulae ad illustrandam embryogenesin hominis et mammalium (1844–1849). In these studies the specimens of cyclopes of man and mammals, still present in the collection of the Museum Vrolik in the Department of Anatomy and Embryology of the University of Amsterdam, were described and illustrated with beautiful lithographs. The collection consists of five human cyclopes and nineteen other cyclopic mammals. These mammals are pigs, lambs and a cat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00156976
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  • 8
    Electronic Resource
    Electronic Resource
    Can dobutamine echocardiography distinguish necrotic from ischemic myocardium, early after myocardial infarction? (1995)
    Springer
    The international journal of cardiovascular imaging 11 (1995), S. 171-175 
    Details
    ISSN: 1573-0743
    Keywords: stress echocardiography ; myocardial infarction ; myocardial ischemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to evaluate the usefulness of dobutamine echocardiography (DE) in distinguishing necrotic from ischemic myocardium in infarct zones. We performed DE in 39 patients, 3 to 5 days after admission for a first, acute myocardial infarction, treated with thrombolysis. DE was considered positive if wall motion in the infarct zone worsened progressively during increasing dose of dobutamine or if wall motion in the infarct zone initially improved at low dose of dobutamine and deteriorated at higher dose. The results of DE were correlated to the evolution of wall motion in the infarct zone after 3 months and to the need for supplementary balloon dilatation. In 15 of the 39 patients, there was evidence of residual ischemia in the infarct zone. Twenty of the 39 patients had a positive dobutamine echocardiogram. Eleven of these 20 patients had evidence of residual ischemia in the infarct zone. They showed generalized changes of wall motion in the total infarct territory during DE. The other 9 patients demonstrated only localized changes of wall motion in isolated segments of the infarct zone during DE. None of these patients had evidence of residual ischemia. In conclusion: DE seems worthwhile in the detection of residual ischemia in the region of infarction. To reduce the number of false positive DE early after myocardial infarction, only extensive changes of wall motion in the total infarct territory should be accepted as indicative of residual ischemia in the infarct zone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01143106
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  • 9
    Electronic Resource
    Electronic Resource
    Spectral analysis of atrial and venous pressure waves: Methods and results (1987)
    Springer
    Medical & biological engineering & computing 25 (1987), S. 96-100 
    Details
    ISSN: 1741-0444
    Keywords: Fast Fourier transform ; Heart rate ; Mean and phasic venous pressure ; Signal analysis ; Spectral analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442829
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  • 10
    Electronic Resource
    Electronic Resource
    Knowledge-based system for the three-dimensional reconstruction of blood vessels from two angiographic projections (1991)
    Springer
    Medical & biological engineering & computing 29 (1991), S. NS27 
    Details
    ISSN: 1741-0444
    Keywords: Angiograms ; Dynamic programming ; Knowledge-based ; Quantification ; Stenosis ; Three-dimensional reconstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A knowledge-based system for the three-dimensional reconstruction of blood vessels from wide-angle coronary and stereoscopic cerebral angiographic projections is developed. For the reconstruction of the coronary vessels, the left coronary artery (LCA) is automatically labelled on standard RAO and LAO projections, using anatomical models of the LCA. The labelling system succeeds in giving the most important coronary arteries a correct anatomical label. These labelling results enable us to find corresponding segments in both images. In the case of the reconstruction of the cerebral vessels however, such an anatomical model is clearly unavailable. To find corresponding segments, small-angle projections must be relied on, resulting in very similar images. Owing to the small angular separation between both projections, the three-dimensional reconstruction will be less accurate. Once the corresponding segments in both projections are obtained, the three-dimensional artery trajectory is reconstructed with dynamic programming techniques. The three-dimensional reconstructed coronary vessels are also used for an automatic quantification of stenotic lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02446099
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